1,794 research outputs found

    Foucault, Kant, Deleuze, and the problem of political agency

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    Political agency concerns the transformation of the conditions of social organization through collective action. In order to treat the set of necessary conditions for such agency, I develop a detailed reconstruction of Michel Foucault\u27s political philosophy, placed in relation to the work of Immanuel Kant and Gilles Deleuze. I argue that the key to Foucault\u27s political thought is contained in two crucial but neglected concepts, verticality andtransversality, and that the systematic exposition of these concepts yields an account of what must obtain for political agency to be possible, realizable, and sustainable

    Effects of environmental variation during seed production on seed dormancy and germination

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    The environment during seed production has major impacts on the behaviour of progeny seeds. It can be shown that for annual plants temperature perception over the whole life history of the mother can affect the germination rate of progeny, and instances have been documented where these affects cross whole generations. Here we discuss the current state of knowledge of signal transduction pathways controlling environmental responses during seed production, focusing both on events that take place in the mother plant and those that occur directly as a result of environmental responses in the developing zygote. We show that seed production environment effects are complex, involving overlapping gene networks active independently in fruit, seed coat, and zygotic tissues that can be deconstructed using careful physiology alongside molecular and genetic experiments

    Analyses of some apatites containing manganese

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    Pleiotropy in developmental regulation by flowering‐pathway genes: is it an evolutionary constraint?

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    Pleiotropy occurs when one gene influences more than one trait, contributing to genetic correlations among traits. Consequently, it is considered a constraint on the evolution of adaptive phenotypes because of potential antagonistic selection on correlated traits, or, alternatively, preservation of functional trait combinations. Such evolutionary constraints may be mitigated by the evolution of different functions of pleiotropic genes in their regulation of different traits. Arabidopsis thaliana flowering-time genes, and the pathways in which they operate, are among the most thoroughly studied regarding molecular functions, phenotypic effects, and adaptive significance. Many of them show strong pleiotropic effects. Here, we review examples of pleiotropy of flowering-time genes and highlight those that also influence seed germination. Some genes appear to operate in the same genetic pathways when regulating both traits, whereas others show diversity of function in their regulation, either interacting with the same genetic partners but in different ways or potentially interacting with different partners. We discuss how functional diversification of pleiotropic genes in the regulation of different traits across the life cycle may mitigate evolutionary constraints of pleiotropy, permitting traits to respond more independently to environmental cues, and how it may even contribute to the evolutionary divergence of gene function across taxa.Fil: Auge, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Fisiología, Biología Molecular y Celular; ArgentinaFil: Penfield, Steven. John Innes Centre; Reino UnidoFil: Donohue, Kathleen. University of Duke; Estados Unido

    50 Years of Test (Un)fairness: Lessons for Machine Learning

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    Quantitative definitions of what is unfair and what is fair have been introduced in multiple disciplines for well over 50 years, including in education, hiring, and machine learning. We trace how the notion of fairness has been defined within the testing communities of education and hiring over the past half century, exploring the cultural and social context in which different fairness definitions have emerged. In some cases, earlier definitions of fairness are similar or identical to definitions of fairness in current machine learning research, and foreshadow current formal work. In other cases, insights into what fairness means and how to measure it have largely gone overlooked. We compare past and current notions of fairness along several dimensions, including the fairness criteria, the focus of the criteria (e.g., a test, a model, or its use), the relationship of fairness to individuals, groups, and subgroups, and the mathematical method for measuring fairness (e.g., classification, regression). This work points the way towards future research and measurement of (un)fairness that builds from our modern understanding of fairness while incorporating insights from the past.Comment: FAT* '19: Conference on Fairness, Accountability, and Transparency (FAT* '19), January 29--31, 2019, Atlanta, GA, US

    In situ chemically specific mapping of agrochemical seed coatings using stimulated Raman scattering microscopy.

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    This is the author accepted manuscript. The final version is available from Wiley-VCH-Verlag via the DOI in this record.Providing sufficient, healthy food for the increasing global population is putting a great deal of pressure on the agrochemical industry to maximise crop yields without sustaining environmental damage. The growth and yield of every plant with sexual reproduction, depends on germination and emergence of sown seeds, which is affected greatly by seed disease. This can be most effectively controlled by treating seeds with pesticides before they are sown. An effective seed coating treatment requires a high surface coverage and adhesion of active ingredients onto the seed surface and the addition of adhesive agents in coating formulations plays a key role in achieving this. Although adhesive agents are known to enhance seed germination, little is understood about how they affect surface distribution of actives and how formulations can be manipulated to rationally engineer seed coating preparations with optimized coverage and efficacy. We show, for the first time, that stimulated Raman scattering (SRS) microscopy can be used to map the seed surface with microscopic spatial resolution and with chemical specificity to identify formulation components distributed on the seed surface. This represents a major advance in our capability to rationally engineer seed coating formulations with enhanced efficacy.We thank the funding from the Biotechnology and Biological Sciences Research Council (BBSRC, BB/M017915/1 and BB/K013602/1)

    A VEL3 histone deacetylase complex establishes a maternal epigenetic state controlling progeny seed dormancy

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    Mother plants play an important role in the control of dormancy and dispersal characters of their progeny. In Arabidopsis seed dormancy is imposed by the embryo-surrounding tissues of the endosperm and seed coat. Here we show that VERNALIZATION5/VIN3-LIKE 3 (VEL3) maintains maternal control over progeny seed dormancy. Acting early in endosperm development, it establishes an epigenetic state that primes the depth of primary seed dormancy that will be reached later during seed maturation. VEL3 relocates MSI1 to the nucleolus and associates with other components of the histone deacetylase complex (HDAC). Furthermore VEL3 preferentially associates with pericentromeric chromatin and is required for deacetylation and H3K27me3 deposition in the central cell. Interestingly, the epigenetic state established by the maternal VEL3 is retained in mature seeds, and controls seed dormancy in part through the repression of programmed cell death-associated gene ORE1. Our data demonstrates a novel mechanism by which maternal control of progeny seed physiology persists post-shedding, maintaining parental control of seed behaviour

    Physical interpretation of the Wigner rotations and its implications for relativistic quantum information

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    We present a new treatment for the spin of a massive relativistic particle in the context of quantum information based on a physical interpretation of the Wigner rotations, obtaining different results in relation to the previous works. We are lead to the conclusions that it is not possible to define a reduced density matrix for the particle spin and that the Pauli-Lubanski (or similar) spin operators are not suitable to describe measurements where spin couples to an electromagnetic field in the measuring apparatus. These conclusions contradict the assumptions made by most of the previous papers on the subject. We also propose an experimental test of our formulation.Comment: 10 pages, 2 figures. Several changes were made on the text. One extra example was include

    Electromagnetic self-forces and generalized Killing fields

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    Building upon previous results in scalar field theory, a formalism is developed that uses generalized Killing fields to understand the behavior of extended charges interacting with their own electromagnetic fields. New notions of effective linear and angular momenta are identified, and their evolution equations are derived exactly in arbitrary (but fixed) curved spacetimes. A slightly modified form of the Detweiler-Whiting axiom that a charge's motion should only be influenced by the so-called "regular" component of its self-field is shown to follow very easily. It is exact in some interesting cases, and approximate in most others. Explicit equations describing the center-of-mass motion, spin angular momentum, and changes in mass of a small charge are also derived in a particular limit. The chosen approximations -- although standard -- incorporate dipole and spin forces that do not appear in the traditional Abraham-Lorentz-Dirac or Dewitt-Brehme equations. They have, however, been previously identified in the test body limit.Comment: 20 pages, minor typos correcte
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