A critical review of modern approaches for multidimensional energy poverty measurement

Recent efforts to measure energy poverty more comprehensively attempt to redress the shortcomings of binary metrics that remain in common use. However, significant challenges remain both with the construction of the new measurement frameworks and their application. The paper presents an analysis of recent multidimensional measurement approaches and applications to draw inferences on the implications of applying these for the measurement of energy access and in informing policies aimed at improving it. The assessment suggests that despite progress having been made in capturing the multidimensional nature of energy poverty, the new measures are currently too complex to operationalize at the global level and too prescriptive to gain acceptance in diverse national contexts. Further efforts are thus required to consolidate and simplify the new frameworks for global tracking purposes, and to adapt and modify these to specific country contexts to inform national policy and planning. A subset of key energy poverty dimensions and uniform set of indicators need to be shortlisted for the purposes of global comparisons, while specific national tracking efforts can apply dimensions and thresholds most suited to accurately capture energy poverty and its drivers in a given context

Qualität der Arbeit: Eine Untersuchung für Ost- und Westdeutschland für die Jahre 1994 und 2009

“Quality of work” – a mainly subjective judgement of employees about their work and the corresponding conditions gained momentum over the last decades. But contrary to quantitative aspects of work and worklife, the term “quality of work” is rather hard to measure and it consists of a mixture of many single indicators related to the worklife of employees. The spectrum of these single indicators range from health considerations up to a flexible management of the work time over a month or a year. The present work contributes to the discussion about the quality of work by introducing additional single indicators into the debate. These are commuting, carreer opportunities within a firm, individual satisfaction with the work income, and a correspondence between formal qualification and the present job. The investigation distinguishes between East and West Germany as well as between age cohorts and the qualification of the interviewed persons. The results are based on the GSOEP for the years 1994 and 2009. Looking at these two years we expect some insights into possible changes in the judgement with respect to the quality of work especially for East German employees shortly after the fall of the wall and nowadays. These insights should help to draw conclusions if East and West German employees are still different in their judgements or if a process of convergence in opions occurred.

Impacts of Grid Electricity Access on Rural Non-Farm Entrepreneurship and Employment in Ethiopia and Nigeria

Rural electricity supply is broadly considered a key driver of the structural transformation away from a dependence on agricultural livelihoods. Nevertheless, the causal effect of improving electricity access on the diversification of rural livelihoods away from agricultural incomes remains poorly understood. Recent systematic syntheses of electrification impacts in literature confirm that there remains limited quasi-experimental quantitative evidence describing the effects of electrification on non-farm entrepreneurship and labor market outcomes in Sub-Saharan African countries. In this report, we investigate the causal effects of household-level electrification on household non-farm entrepreneurship and employment trends in rural Ethiopia and Nigeria, contributing to the literature in terms of the geographical region of analysis and through the application of modern quasi-experimental methods. We analyze household-level observational panel datasets collected under the World Bank’s Living Standards Measurement Survey (LSMS) program, between 2010 and 2015. Our analysis indicates that rural household electrification alone was insufficient to trigger shifts in household non-farm entrepreneurship and labour market outcomes in the 2-4 years following grid connection. These findings are aligned with contemporary rural electrification impact literature urging caution in the interpretation of descriptive and potentially biased analyses that are unable to effectively disentangle the many co-determinants of non-farm entrepreneurship and labour market outcomes with respect to electrification

Direct Measurement of Quantum Confinement Effects at Metal to Quantum-Well Nanocontacts

Model metal-semiconductor nanostructure Schottky nanocontacts were made on cleaved heterostructures containing GaAs quantum wells (QWs) of varying width and were locally probed by ballistic electron emission microscopy. The local Schottky barrier was found to increase by ∼0.140 eV as the QW width was systematically decreased from 15 to 1 nm, due mostly to a large (∼0.200 eV) quantum-confinement increase to the QW conduction band. The measured barrier increase over the full 1 to 15 nm QW range was quantitatively explained when local "interface pinning" and image force lowering effects are also considered

Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture

Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion in one of their eight viral RNAs (vRNAs) rendering them replication-incompetent. However, they can propagate alongside their homologous standard virus (STV) during infection in a competition for cellular and viral resources. So far, experimental and modeling studies for IAV have focused on either the intracellular or the cell population level when investigating the interaction of STVs and DIPs. To examine these levels simultaneously, we conducted a series of experiments using highly different multiplicities of infections for STVs and DIPs to characterize virus replication in Madin-Darby Canine Kidney suspension cells. At several time points post infection, we quantified virus titers, viable cell concentration, virus-induced apoptosis using imaging flow cytometry, and intracellular levels of vRNA and viral mRNA using real-time reverse transcription qPCR. Based on the obtained data, we developed a mathematical multiscale model of STV and DIP co-infection that describes dynamics closely for all scenarios with a single set of parameters. We show that applying high DIP concentrations can shut down STV propagation completely and prevent virus-induced apoptosis. Interestingly, the three observed viral mRNAs (full-length segment 1 and 5, defective interfering segment 1) accumulated to vastly different levels suggesting the interplay between an internal regulation mechanism and a growth advantage for shorter viral RNAs. Furthermore, model simulations predict that the concentration of DIPs should be at least 10000 times higher than that of STVs to prevent the spread of IAV. Ultimately, the model presented here supports a comprehensive understanding of the interactions between STVs and DIPs during co-infection providing an ideal platform for the prediction and optimization of vaccine manufacturing as well as DIP production for therapeutic use

Short- and long-term effects of 56Fe irradiation on cognition and hippocampal DNA methylation and gene expression.

BackgroundAstronauts are exposed to 56Fe ions that may pose a significant health hazard during and following prolonged missions in deep space. We showed previously that object recognition requiring the hippocampus, a structure critical for cognitive function, is affected in 2-month-old mice irradiated with 56Fe ions. Here we examined object recognition in 6-month-old mice irradiated with 56Fe ions, a biological age more relevant to the typical ages of astronauts. Moreover, because the mechanisms mediating the detrimental effects of 56Fe ions on hippocampal function are unclear, we examined changes in hippocampal networks involved in synaptic plasticity and memory, gene expression, and epigenetic changes in cytosine methylation (5mC) and hydroxymethylation (5hmC) that could accompany changes in gene expression. We assessed the effects of whole body 56Fe ion irradiation at early (2 weeks) and late (20 weeks) time points on hippocampus-dependent memory and hippocampal network stability, and whether these effects are associated with epigenetic changes in hippocampal DNA methylation (both 5mC and 5hmC) and gene expression.ResultsAt the two-week time point, object recognition and network stability were impaired following irradiation at the 0.1 and 0.4 Gy dose, but not following irradiation at the 0.2 Gy dose. No impairments in object recognition or network stability were seen at the 20-week time point at any irradiation dose used. Consistent with this pattern, the significance of pathways for gene categories for 5hmC was lower, though not eliminated, at the 20-week time point compared to the 2-week time point. Similarly, significant changes were observed for 5mC gene pathways at the 2-week time point, but no significant gene categories were observed at the 20-week time point. Only the 5hmC changes tracked with gene expression changes.ConclusionsDose- and time-dependent epigenomic remodeling in the hippocampus following 56Fe ion exposure correlates with behavioral changes

Bi-directional and shared epigenomic signatures following proton and 56Fe irradiation.

The brain's response to radiation exposure is an important concern for patients undergoing cancer therapy and astronauts on long missions in deep space. We assessed whether this response is specific and prolonged and is linked to epigenetic mechanisms. We focused on the response of the hippocampus at early (2-weeks) and late (20-week) time points following whole body proton irradiation. We examined two forms of DNA methylation, cytosine methylation (5mC) and hydroxymethylation (5hmC). Impairments in object recognition, spatial memory retention, and network stability following proton irradiation were observed at the two-week time point and correlated with altered gene expression and 5hmC profiles that mapped to specific gene ontology pathways. Significant overlap was observed between DNA methylation changes at the 2 and 20-week time points demonstrating specificity and retention of changes in response to radiation. Moreover, a novel class of DNA methylation change was observed following an environmental challenge (i.e. space irradiation), characterized by both increased and decreased 5hmC levels along the entire gene body. These changes were mapped to genes encoding neuronal functions including postsynaptic gene ontology categories. Thus, the brain's response to proton irradiation is both specific and prolonged and involves novel remodeling of non-random regions of the epigenome

Nanometer-resolution measurement and modeling of lateral variations of the effective work function at the bilayer Pt/Al/SiO2 interface

A ballistic electron emission microscopy (BEEM) comparison of the dependence on gate voltage of the average energy barrier of a metal bilayer Pt/Al/ SiO2 /Si sample and a Pt/ SiO2 /Si sample suggests that the metal/oxide interface of the Pt/Al/ SiO2 /Si sample is laterally inhomogeneous at nm length scales. However, BEEM images of the bilayer sample do not show significantly larger lateral variations than observed on a (uniform) Pt/ SiO2 /Si sample, indicating that any inhomogeneous "patches" of lower-energy barrier height have size smaller than the lateral resolution of BEEM, estimated for these samples to be ???10nm. Finite element electrostatic simulations of an assumed inhomogeneous interface with nm size patches of different effective work function can fit the experimental data of the bilayer sample much better than an assumed homogenous interface, indicating that the bilayer film is laterally inhomogeneous at the nm scale.open2

Management actions to address the climate emergency: Motivations and barriers for SMEs and other societal micro/meso-level groups

Initiatives to tackle the climate emergency have tended to focus on large-scale actions that governments and investors (societal macro-levels) can take and smaller-scale individual habits, with limited attention given to the groups that form society between those ends of the spectrum (societal micro/meso-levels). This research aims to traverse that gap by studying three societal micro/meso-level groups; from the private, public and voluntary sectors, as represented by business, community and campaign groups. Existing literature and focus groups are used to identify what motivates actions on climate change, while exposing barriers that may drive choices of inaction. The study shows that concerns for the future and personal ethics play vital roles across business, community and campaign groups, while the principal barriers include difficulties in accessing support schemes and changes in political priorities. Better networking and knowledge exchange are considered essential for meaningful progress. This provides a new framework for management education to support organisations in tackling climate-related issues. Action guides may be developed and task-forces trained to provide hands-on support, especially for SMEs and local communities. The enthusiasm of younger people and campaigners, combined with others’ experiences, would create a powerful platform for climate emergency actions

Short-run effects of grid electricity access on rural non-farm entrepreneurship and employment in Ethiopia and Nigeria

Empirical evaluation of the household-level economic effects of electricity access in rural regions has challenged researchers due to data scarcity issues and identification challenges. Previous studies provide mixed evidence depending on the context and the empirical approach adopted. Continued efforts towards a robust understanding of this linkage are necessary for guiding the design of rural electricity access and economic development policies. Here we carry out a difference-in-differences analysis with staggered treatment timing, revisiting prior work reporting short-run effects of rural electrification on household non-farm entrepreneurship and employment trends in Ethiopia and Nigeria between 2010–2015. Our results indicate that rural electrification considered alone was insufficient to trigger shifts in non-farm entrepreneurship and non-farm household employment outcomes in the 2–4 years following grid connection in either country. We do find some evidence in Nigeria of farm employment intensification over this short-term. Our work contributes to improving the understanding of the causal pathway in question while also highlighting the limitations of short-term survey datasets in pursuing this goal