Papillary fibroelastoma of the left atrial wall: a case report

Cardiac papillary fibroelastoma is a rare, benign cardiac tumor. It often arises from valvular endocardium, and non-valvular endocardial location is rare. Although transthoracic echocardiography is usually sufficient for the diagnosis of most cardiac tumors, small tumors such as papillary fibroelastoma may be missed. Transesophageal echocardiography is superior to transthoracic echocardiography in diagnosing these tumors. Despite their benign histology, and independent of their size, they should be resected surgically because of their high potential for embolization

Pericyte Seeded Dual Peptide Scaffold with Improved Endothelialization for Vascular Graft Tissue Engineering

Raw research data supporting the paper: Campagnolo, P. et al., Pericyte seeded dual peptide scaffold with improved endothelialization for vascular graft tissue engineering, 2016, Advanced Healthcare Materials, 5(23), 3046-3055

Koroner baypas hastalarında harmonik skalpel ile lima çıkarılmasının sternum kanlanması ve greft morfolojisi üzerine etkileri

Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.[Abstarct Not Available

Submitral left ventricular aneurysm: a rare but challenging pathology to treat

Submitral left ventricular aneurysm is a rare cardiac pathology. Etiology remains still mysterious, but it is believed to be due to a congenital defect of the fibrous layer of the atrioventricular junction. Surgical closure of aneurysm rim is the therapy of choice, despite the diversity of surgical approaches and techniques. We present a young patient operated with a transmitral approach in our clinic. Posterior mitral leaflet (PML) detachment and then extension valvuloplasty by using autologous pericardium was performed in order to save the native mitral valve. We believe that respecting the integrity of native valve is of crucial importance in this young population of patients

Alcohol pretreatment of small-diameter expanded polytetrafluoroethylene grafts: quantitative analysis of graft healing characteristics in the rat abdominal aorta interposition model

Long-term patency rates of small-diameter expanded polytetrafluoroethylene (ePTFE) vascular prostheses are unsatisfactory. Treatment of ePTFE grafts by alcohol before implantation was reported to increase hydrophilic properties, yielding better endothelialization and cellular in-growth, thus improving graft healing. The effect of alcohol pretreatment on ePTFE grafts and postoperative healing characteristics of wet ePTFE grafts were evaluated in this study. Ten sterile ePTFE grafts (2 mm ID, 30 micro thru-pore, 12 mm long) were implanted in the infrarenal aorta of male Sprague-Dawley rats (324-380 g). Five grafts were treated with ethanol 70% and soaked with saline solution before implantation (wet); five nontreated grafts served as control. All rats were sacrificed after digital subtraction angiography and sampling of the graft for histological investigation after 3 weeks. Histomorphometric analysis was performed for endothelial coverage, cellular in-growth, and intimal hyperplasia. All grafts were patent at the end of 3 weeks in both groups. Histological evaluation revealed significantly better endothelial coverage and prominent infiltration by fibroblasts and lymphocytes in the wet group. Endothelial coverage (31.03 +/- 10.61% vs. 13.03 +/- 9.46%, P = 0.03) and cellular infiltration of grafts (50.91 +/- 8.55% vs. 39.29 +/- 10.70%, P = 0.11) were higher in the wet group. Area of intimal hyperplasia per graft length was also higher in the wet group (5.32 +/- 4.75 microm(2)/microm vs. 2.69 +/- 3.41 microm(2)/microm, P = 0.36). Wetting of ePTFE grafts with ethanol 70% pretreatment before implantation might have a beneficial effect on long-term patency of small-diameter vascular grafts due to facilitated graft healing