Orbital Debris-Debris Collision Avoidance

We focus on preventing collisions between debris and debris, for which there is no current, effective mitigation strategy. We investigate the feasibility of using a medium-powered (5 kW) ground-based laser combined with a ground-based telescope to prevent collisions between debris objects in low-Earth orbit (LEO). The scheme utilizes photon pressure alone as a means to perturb the orbit of a debris object. Applied over multiple engagements, this alters the debris orbit sufficiently to reduce the risk of an upcoming conjunction. We employ standard assumptions for atmospheric conditions and the resulting beam propagation. Using case studies designed to represent the properties (e.g. area and mass) of the current debris population, we show that one could significantly reduce the risk of nearly half of all catastrophic collisions involving debris using only one such laser/telescope facility. We speculate on whether this could mitigate the debris fragmentation rate such that it falls below the natural debris re-entry rate due to atmospheric drag, and thus whether continuous long-term operation could entirely mitigate the Kessler syndrome in LEO, without need for relatively expensive active debris removal.Comment: 13 pages, 8 figures. Accepted for publication in Advances in Space Researc

Facilitating open exchange of data and information

Author Posting. © The Author(s), 2014. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in Earth Science Informatics 8 (2015): 721-739, doi:10.1007/s12145-014-0202-2.By broad consensus, Open Data presents great value. However, beyond that simple statement, there are a number of complex, and sometimes contentious, issues that the science community must address. In this review, we examine the current state of the core issues of Open Data with the unique perspective and use cases of the ocean science community: interoperability; discovery and access; quality and fitness for purpose; and sustainability. The topics of Governance and Data Publication are also examined in detail. Each of the areas covered are, by themselves, complex and the approaches to the issues under consideration are often at odds with each other. Any comprehensive policy on Open Data will require compromises that are best resolved by broad community input. In the final section of the review, we provide recommendations that serve as a starting point for these discussions.The authors acknowledge the support of the National Science Foundation through Grant Award No. OCE-1143683.2016-01-0

Psychological flexibility and attitudes toward evidence-based interventions by amyotrophic lateral sclerosis patients

Objective Declining a percutaneous endoscopic gastrostomy (PEG) or non-invasive ventilation (NIV) by people with amyotrophic lateral sclerosis (ALS) is often contrary to advice provided by health-care-professionals guided by evidence-based principles. This study proposes relational frame theory (RFT) to offer a viable explanation of this phenomenon. Design A total of 35 people (14 female, 21 male) aged between 34 and 73 years, with ALS, participated in this cross-sectional research. Main outcome measures This research examined the predictive power and interaction effect of psychological flexibility (the fundamental construct of RFT) and psychological well-being on attitudes toward intervention options. Results Participants with high psychological flexibility reported lower depression, anxiety, and stress, and higher quality of life. In addition, psychological flexibility was predictive of a participant’s understanding and acceptance of a PEG as an intervention option. Psychological flexibility was not found to be a significant predictor of understanding and acceptance of NIV. Conclusion Although the criterion measure had not been piloted or validated outside of the current study and asks about expected rather than actual acceptance, findings suggest that applied RFT may be helpful for clients with ALS

A modern coastal ocean observing system using data from advanced satellite and in situ sensors – an example

Report of the Ocean Observation Research Coordination Network In-situ-Satellite Observation Working GroupThis report is intended to illustrate and provide recommendations for how ocean observing systems of the next decade could focus on coastal environments using combined satellite and in situ measurements. Until recently, space-based observations have had surface footprints typically spanning hundreds of meters to kilometers. These provide excellent synoptic views for a wide variety of ocean characteristics. In situ observations are instead generally point or linear measurements. The interrelation between space-based and in-situ observations can be challenging. Both are necessary and as sensors and platforms evolve during the next decade, the trend to facilitate interfacing space and in-situ observations must continue and be expanded. In this report, we use coastal observation and analyses to illustrate an observing system concept that combines in situ and satellite observing technologies with numerical models to quantify subseasonal time scale transport of freshwater and its constituents from terrestrial water storage bodies across and along continental shelves, as well as the impacts on some key biological/biogeochemical properties of coastal waters.Ocean Research Coordination Network and the National Science Foundatio

Folding Pathways of Prion and Doppel

The relevance of various residue positions for the stability and the folding characteristics of the prion protein are investigated by using molecular dynamics simulations of models exploiting the topology of the native state. Highly significant correlations are found between the most relevant sites in our analysis and the single point mutations known to be associated with the arousal of the genetic forms of prion disease (caused by the conformational change from the cellular to the scrapie isoform). Considerable insight into the conformational change is provided by comparing the folding process of prion and doppel (a newly discovered protein) sharing very similar native state topology: the folding pathways of the former can be grouped in two main classes according to which tertiary structure contacts are formed first enroute to the native state. For the latter a single class of pathways leads to the native state. Our results are consistent and supportive of the recent experimental findings that doppel lacks the scrapie isoform and that such remarkably different behavior results from differences in the region containing the two $\beta-$strands and the intervening helix.Comment: 16 pages, 2 tables, 5 figure

Sagittal Bone Saw With Orbital Blade Motion for Improved Cutting Efficiency

Sagittal bone saws are used by orthopedic surgeons for resection of bone; for example in total joint arthroplasty of the hip and knee. In order to prevent damage to surrounding tissue, sagittal saw blades typically oscillate through a small angle, resulting in reduced cutting rates due to short stroke lengths. To improve bone cutting efficiency, sagittal saws oscillate at high speeds, but this creates frictional heating that can harm bone cells. The focus of this research was to design a new sagittal sawing device for improved cutting efficiency. It was hypothesized that the addition of an impulsive thrust force during the cutting stroke would increase cutting rates in cortical bone. A cam-driven device was developed and tested in bovine cortical bone. The impulsive thrust force was achieved by creating a component of blade motion perpendicular to the cutting direction, i.e., orbital blade motion. At the start of each cutting stroke, the mechanism drove the saw blade into the surface of the bone, increasing the thrust force with the intention of increasing the depth of cut per tooth. As each cutting stroke was completed, the blade was retracted from the surface for the purpose of clearing bone chips. The design parameters investigated were cutting stroke length, thrust stroke length, and blade oscillation frequency. A three-factor, two-level design of experiments approach was used to simultaneously test for the effect of design parameters and their interactions on volumetric cutting rate (n ¼ 32). The addition of orbital blade motion to the sagittal saw improved bone cutting rates over traditional oscillatory motion, especially at lower cutting stroke lengths and higher oscillation frequencies (p < 0.05). However, the magnitude of orbital blade motion based on thrust stroke length was limited by a threshold value of approximately 0.10 mm that when exceeded caused the sagittal saw to rebound from the surface of the bone causing erratic cutting conditions. The factor with the greatest positive effect on cutting rate was oscillation frequency. Cutting rates in cortical bone can be improved with the proposed orbital action sagittal saw

Facilitating open exchange of data and information

By broad consensus, Open Data presents great value. However, beyond that simple statement, there are a number of complex, and sometimes contentious, issues that the science community must address. In this review, we examine the current state of the core issues of Open Data with the unique perspective and use cases of the ocean science community: interoperability; discovery and access; quality and fitness for purpose; and sustainability. The topics of Governance and Data Publication are also examined in detail. Each of the areas covered are, by themselves, complex and the approaches to the issues under consideration are often at odds with each other. Any comprehensive policy on Open Data will require compromises that are best resolved by broad community input. In the final section of the review, we provide recommendations that serve as a starting point for these discussions.This is an author's peer-reviewed manuscript, as accepted by the publisher. The published article is copyrighted by Springer and can be found at: https://doi.org/10.1007/s12145-014-0202-

Beings in their own right? Exploring Children and young people's sibling and twin relationships in the Minority World

This paper examines the contributions that the sociological study of sibship and twinship in the Minority World can make to childhood studies. It argues that, in providing one forum within which to explore children and young people's social relationships, we can add to our understanding of children and young people's interdependence and develop a more nuanced understanding of agency. As emergent subjects, children, young people and adults are in a process of ‘becoming’. However, this does not mean that they can ‘become’ anything they choose to. The notion of negotiated interdependence (Punch 2002) is useful in helping us to grasp the contingent nature of children and young people's agency