29 research outputs found
Dispersion control for matter waves and gap solitons in optical superlattices
We present a numerical study of dispersion manipulation and formation of
matter-wave gap solitons in a Bose-Einstein condensate trapped in an optical
superlattice. We demonstrate a method for controlled generation of matter-wave
gap solitons in a stationary lattice by using an interference pattern of two
condensate wavepackets, which mimics the structure of the gap soliton near the
edge of a spectral band. The efficiency of this method is compared with that of
gap soliton generation in a moving lattice recently demonstrated experimentally
by Eiermann et al. [Phys. Rev. Lett. 92, 230401 (2004)]. We show that, by
changing the relative depths of the superlattice wells, one can fine-tune the
effective dispersion of the matter waves at the edges of the mini-gaps of the
superlattice Bloch-wave spectrum and therefore effectively control both the
peak density and the spatial width of the emerging gap solitons.Comment: 8 pages, 9 figures; modified references in Section 2; minor content
changes in Sections 1 and 2 and Fig. 9 captio
Bosons in Disordered Optical Potentials
In this work we systematically investigate the condensate properties,
superfluid properties and quantum phase transitions in interacting Bose gases
trapped in disordered optical potentials. We numerically solve the Bose-Hubbard
Hamiltonian exactly for different: (a) types of disorder, (b) disorder
strengths, and (c) interatomic interactions. The three types of disorder
studied are: quasiperiodic disorder, uniform random disorder and random
speckle-type disorder. We find that the Bose glass, as identified by Fisher et
al [Phys. Rev. B {\bf 40}, 546 (1989)], contains a normal condensate component
and we show how the three different factors listed above affect it.Comment: 4 pages, 4 figures (low res) v2 Title,Abstract,Introduction: changes;
Figure 3: Add label to axi
Bose-Einstein Condensates in Optical Lattices: Band-Gap Structure and Solitons
We analyze the existence and stability of spatially extended (Bloch-type) and
localized states of a Bose-Einstein condensate loaded into an optical lattice.
In the framework of the Gross-Pitaevskii equation with a periodic potential, we
study the band-gap structure of the matter-wave spectrum in both the linear and
nonlinear regimes. We demonstrate the existence of families of spatially
localized matter-wave gap solitons, and analyze their stability in different
band gaps, for both repulsive and attractive atomic interactions
Height-diameter allometry and above ground biomass in tropical montane forests: Insights from the Albertine Rift in Africa
Tropical montane forests provide an important natural laboratory to test ecological theory. While it is well-known that some aspects of forest structure change with altitude, little is known on the effects of altitude on above ground biomass (AGB), particularly with regard to changing height-diameter allometry. To address this we investigate (1) the effects of altitude on height-diameter allometry, (2) how different height-diameter allometric models affect above ground biomass estimates; and (3) how other forest structural, taxonomic and environmental attributes affect above ground biomass using 30 permanent sample plots (1-ha; all trees ≥ 10 cm diameter measured) established between 1250 and 2600 m asl in Kahuzi Biega National Park in eastern Democratic Republic of Congo. Forest structure and species composition differed with increasing altitude, with four forest types identified. Different height-diameter allometric models performed better with the different forest types, as trees got smaller with increasing altitude. Above ground biomass ranged from 168 to 290 Mg ha-1, but there were no significant differences in AGB between forests types, as tree size decreased but stem density increased with increasing altitude. Forest structure had greater effects on above ground biomass than forest diversity. Soil attributes (K and acidity, pH) also significantly affected above ground biomass. Results show how forest structural, taxonomic and environmental attributes affect above ground biomass in African tropical montane forests. They particularly highlight that the use of regional height-diameter models introduces significant biases in above ground biomass estimates, and that different height-diameter models might be preferred for different forest types, and these should be considered in future studies
Seasonality in Human Zoonotic Enteric Diseases: A Systematic Review
BACKGROUND: Although seasonality is a defining characteristic of many infectious diseases, few studies have described and compared seasonal patterns across diseases globally, impeding our understanding of putative mechanisms. Here, we review seasonal patterns across five enteric zoonotic diseases: campylobacteriosis, salmonellosis, vero-cytotoxigenic Escherichia coli (VTEC), cryptosporidiosis and giardiasis in the context of two primary drivers of seasonality: (i) environmental effects on pathogen occurrence and pathogen-host associations and (ii) population characteristics/behaviour. METHODOLOGY/PRINCIPAL FINDINGS: We systematically reviewed published literature from 1960-2010, resulting in the review of 86 studies across the five diseases. The Gini coefficient compared temporal variations in incidence across diseases and the monthly seasonality index characterised timing of seasonal peaks. Consistent seasonal patterns across transnational boundaries, albeit with regional variations was observed. The bacterial diseases all had a distinct summer peak, with identical Gini values for campylobacteriosis and salmonellosis (0.22) and a higher index for VTEC (Gini  0.36). Cryptosporidiosis displayed a bi-modal peak with spring and summer highs and the most marked temporal variation (Gini = 0.39). Giardiasis showed a relatively small summer increase and was the least variable (Gini = 0.18). CONCLUSIONS/SIGNIFICANCE: Seasonal variation in enteric zoonotic diseases is ubiquitous, with regional variations highlighting complex environment-pathogen-host interactions. Results suggest that proximal environmental influences and host population dynamics, together with distal, longer-term climatic variability could have important direct and indirect consequences for future enteric disease risk. Additional understanding of the concerted influence of these factors on disease patterns may improve assessment and prediction of enteric disease burden in temperate, developed countries
Enhanced Stability of Monomer Fold Correlates with Extreme Drug Resistance of HIV-1 Protease
Importance of the N Terminus of Rous Sarcoma Virus Protease for Structure and Enzymatic Function
All retrovirus proteases (PRs) are homodimers, and dimerization is essential for enzymatic function. The dimer is held together largely by a short four-stranded antiparallel beta sheet composed of the four or five N-terminal amino acid residues and a similar stretch of residues from the C terminus. We have found that the enzymatic and structural properties of Rous sarcoma virus (RSV) PR are exquisitely sensitive to mutations at the N terminus. Deletion of one or three residues, addition of one residue, or substitution of alanine for the N-terminal leucine reduced enzymatic activity on peptide and protein substrates 100- to 1,000-fold. The purified mutant proteins remained monomeric up to a concentration of about 2 mg/ml, as determined by dynamic light scattering. At higher concentrations, dimerization was observed, but the dimer lacked or was deficient in enzymatic activity and thus was inferred to be structurally distinct from a wild-type dimer. The mutant protein lacking three N-terminal residues (ΔLAM), a form of PR occurring naturally in virions, was examined by nuclear magnetic resonance spectroscopy and found to be folded at concentrations where it was monomeric. This result stands in contrast to the report that a similarly engineered monomeric PR of human immunodeficiency virus type 1 is unstructured. Heteronuclear single quantum coherence spectra of the mutant at concentrations where either monomers or dimers prevail were nearly identical. However, these spectra differed from that of the dimeric wild-type RSV PR. These results imply that the chemical environment of many of the amide protons differed and thus that the three-dimensional structure of the ΔLAM PR mutant is different from that of the wild-type PR. The structure of this mutant protein may serve as a model for the structure of the PR domain of the Gag polyprotein and may thus give clues to the initiation of proteolytic maturation in retroviruses