Extreme 3D Face Reconstruction: Seeing Through Occlusions

Existing single view, 3D face reconstruction methods can produce beautifully detailed 3D results, but typically only for near frontal, unobstructed viewpoints. We describe a system designed to provide detailed 3D reconstructions of faces viewed under extreme conditions, out of plane rotations, and occlusions. Motivated by the concept of bump mapping, we propose a layered approach which decouples estimation of a global shape from its mid-level details (e.g., wrinkles). We estimate a coarse 3D face shape which acts as a foundation and then separately layer this foundation with details represented by a bump map. We show how a deep convolutional encoder-decoder can be used to estimate such bump maps. We further show how this approach naturally extends to generate plausible details for occluded facial regions. We test our approach and its components extensively, quantitatively demonstrating the invariance of our estimated facial details. We further provide numerous qualitative examples showing that our method produces detailed 3D face shapes in viewing conditions where existing state of the art often break down.Comment: Accepted to CVPR'18. Previously titled: "Extreme 3D Face Reconstruction: Looking Past Occlusions

Effective Face Frontalization in Unconstrained Images

"Frontalization" is the process of synthesizing frontal facing views of faces appearing in single unconstrained photos. Recent reports have suggested that this process may substantially boost the performance of face recognition systems. This, by transforming the challenging problem of recognizing faces viewed from unconstrained viewpoints to the easier problem of recognizing faces in constrained, forward facing poses. Previous frontalization methods did this by attempting to approximate 3D facial shapes for each query image. We observe that 3D face shape estimation from unconstrained photos may be a harder problem than frontalization and can potentially introduce facial misalignments. Instead, we explore the simpler approach of using a single, unmodified, 3D surface as an approximation to the shape of all input faces. We show that this leads to a straightforward, efficient and easy to implement method for frontalization. More importantly, it produces aesthetic new frontal views and is surprisingly effective when used for face recognition and gender estimation

A Spectacular Hα\alpha Complex in Virgo: Evidence for a Collision Between M86 and NGC 4438 and Implications for Collisional ISM Heating of Ellipticals

Deep wide-field H$\alpha$+[NII] imaging around the Virgo cluster giant elliptical galaxy M86 reveals a highly complex and disturbed ISM/ICM. The most striking feature is a set of H$\alpha$ filaments which clearly connect M86 with the nearby disturbed spiral NGC 4438 (23$'$=120 kpc projected away), providing strong evidence for a previously unrecognized collision between them. Spectroscopy of selected regions show a fairly smooth velocity gradient between M86 and NGC 4438, consistent with the collision scenario. Such a collision would impart significant energy into the ISM of M86, probably heating the gas and acting to prevent the gas from cooling to form stars. We propose that cool gas stripped from NGC 4438 during the collision and deposited in its wake is heated by shocks, ram pressure drag, or thermal conduction, producing most of the H$\alpha$ filaments. Some H$\alpha$ filaments are associated with the well-known ridge of bright X-ray emission to the NW of the nucleus, suggesting that the collision is responsible for peculiarities of M86 previously ascribed to other effects. M86 is radio-quiet, thus AGN heating is unlikely to play a significant role. The M86 system has implications for understanding the role of gravitational interactions in the heating of the ISM in ellipticals, and how collisions in clusters transform galaxies.Comment: 6 pages, 2 figures. For high-resolution images, see http://www.astro.yale.edu/tal/research/index.htm

Nearby early-type galaxies with ionized gas. The UV emission from GALEX observations

We present GALEX far-ultraviolet (FUV, $\lambda_{eff}$=1538 \AA) and near-ultraviolet (NUV, $\lambda_{eff}$=2316 \AA) surface photometry of 40 early-type galaxies (ETGs) selected from a wider sample of 65 nearby ETGs showing emission lines in their optical spectra. We derive FUV and NUV surface brightness profiles, (FUV-NUV) colour profiles and D$_{25}$ integrated magnitudes. We extend the photometric study to the optical {\it r} band from SDSS imaging for 14 of these ETGs. In general, the (FUV-NUV) radial colour profiles become redder with galactocentric distance in both rejuvenated ($\leq 4$ Gyr) and old ETGs. Colour profiles of NGC 1533, NGC 2962, NGC 2974, NGC 3489, and IC 5063 show rings and/or arm-like structures, bluer than the body of the galaxy, suggesting the presence of recent star formation. Although seven of our ETGs show shell systems in their optical image, only NGC 7135 displays shells in the UV bands. We characterize the UV and optical surface brightness profiles, along the major axis, using a Sersic law. The Sersic law exponent, $n$, varies from 1 to 16 in the UV bands. S0 galaxies tend to have lower values of $n$ ($\leq5$). The Sersic law exponent $n=4$ seems to be a watershed: ETGs with $n>4$ tend to have [$\alpha$/Fe] greater than 0.15, implying a short star-formation time scale. We find a significant correlation between the FUV$-$NUV colour and central velocity dispersions $\sigma$, with the UV colours getting bluer at larger $\sigma$. This trend is likely driven by a combined effect of `downsizing' and of the mass-metallicity relation.Comment: Accepted for publication in MNRAS, 33 pages, 7 figure

Effect of SARS-CoV-2 proteins on vascular permeability.

Severe acute respiratory syndrome (SARS)-CoV-2 infection leads to severe disease associated with cytokine storm, vascular dysfunction, coagulation, and progressive lung damage. It affects several vital organs, seemingly through a pathological effect on endothelial cells. The SARS-CoV-2 genome encodes 29 proteins, whose contribution to the disease manifestations, and especially endothelial complications, is unknown. We cloned and expressed 26 of these proteins in human cells and characterized the endothelial response to overexpression of each, individually. Whereas most proteins induced significant changes in endothelial permeability, nsp2, nsp5_c145a (catalytic dead mutant of nsp5), and nsp7 also reduced CD31, and increased von Willebrand factor expression and IL-6, suggesting endothelial dysfunction. Using propagation-based analysis of a protein–protein interaction (PPI) network, we predicted the endothelial proteins affected by the viral proteins that potentially mediate these effects. We further applied our PPI model to identify the role of each SARS-CoV-2 protein in other tissues affected by coronavirus disease (COVID-19). While vali-dating the PPI network model, we found that the tight junction (TJ) proteins cadherin-5, ZO-1, and β-catenin are affected by nsp2, nsp5_c145a, and nsp7 consistent with the model prediction. Overall, this work identifies the SARS-CoV-2 proteins that might be most detrimental in terms of endothelial dysfunction, thereby shedding light on vascular aspects of COVID-1

Cooperative Transition between Open and Closed Conformations in Potassium Channels

Potassium (K+) ion channels switch between open and closed conformations. The nature of this important transition was revealed by comparing the X-ray crystal structures of the MthK channel from Methanobacterium thermoautotrophicum, obtained in its open conformation, and the KcsA channel from Streptomyces lividans, obtained in its closed conformation. We analyzed the dynamic characteristics and energetics of these homotetrameric structures in order to study the role of the intersubunit cooperativity in this transition. For this, elastic models and in silico alanine-scanning mutagenesis were used, respectively. Reassuringly, the calculations manifested motion from the open (closed) towards the closed (open) conformation. The calculations also revealed a network of dynamically and energetically coupled residues. Interestingly, the network suggests coupling between the selectivity filter and the gate, which are located at the two ends of the channel pore. Coupling between these two regions was not observed in calculations that were conducted with the monomer, which emphasizes the importance of the intersubunit interactions within the tetrameric structure for the cooperative gating behavior of the channel

Progress from ASDEX Upgrade experiments in preparing the physics basis of ITER operation and DEMO scenario development

An overview of recent results obtained at the tokamak ASDEX Upgrade (AUG) is given. A work flow for predictive profile modelling of AUG discharges was established which is able to reproduce experimental H-mode plasma profiles based on engineering parameters only. In the plasma center, theoretical predictions on plasma current redistribution by a dynamo effect were confirmed experimentally. For core transport, the stabilizing effect of fast ion distributions on turbulent transport is shown to be important to explain the core isotope effect and improves the description of hollow low-Z impurity profiles. The L-H power threshold of hydrogen plasmas is not affected by small helium admixtures and it increases continuously from the deuterium to the hydrogen level when the hydrogen concentration is raised from 0 to 100%. One focus of recent campaigns was the search for a fusion relevant integrated plasma scenario without large edge localised modes (ELMs). Results from six different ELM-free confinement regimes are compared with respect to reactor relevance: ELM suppression by magnetic perturbation coils could be attributed to toroidally asymmetric turbulent fluctuations in the vicinity of the separatrix. Stable improved confinement mode plasma phases with a detached inner divertor were obtained using a feedback control of the plasma β. The enhanced D α H-mode regime was extended to higher heating power by feedback controlled radiative cooling with argon. The quasi-coherent exhaust regime was developed into an integrated scenario at high heating power and energy confinement, with a detached divertor and without large ELMs. Small ELMs close to the separatrix lead to peeling-ballooning stability and quasi continuous power exhaust. Helium beam density fluctuation measurements confirm that transport close to the separatrix is important to achieve the different ELM-free regimes. Based on separatrix plasma parameters and interchange-drift-Alfvén turbulence, an analytic model was derived that reproduces the experimentally found important operational boundaries of the density limit and between L- and H-mode confinement. Feedback control for the X-point radiator (XPR) position was established as an important element for divertor detachment control. Stable and detached ELM-free phases with H-mode confinement quality were obtained when the XPR was moved 10 cm above the X-point. Investigations of the plasma in the future flexible snow-flake divertor of AUG by means of first SOLPS-ITER simulations with drifts activated predict beneficial detachment properties and the activation of an additional strike point by the drifts

Modelling of the effect of ELMs on fuel retention at the bulk W divertor of JET

Effect of ELMs on fuel retention at the bulk W target of JET ITER-Like Wall was studied with multi-scale calculations. Plasma input parameters were taken from ELMy H-mode plasma experiment. The energetic intra-ELM fuel particles get implanted and create near-surface defects up to depths of few tens of nm, which act as the main fuel trapping sites during ELMs. Clustering of implantation-induced vacancies were found to take place. The incoming flux of inter-ELM plasma particles increases the different filling levels of trapped fuel in defects. The temperature increase of the W target during the pulse increases the fuel detrapping rate. The inter-ELM fuel particle flux refills the partially emptied trapping sites and fills new sites. This leads to a competing effect on the retention and release rates of the implanted particles. At high temperatures the main retention appeared in larger vacancy clusters due to increased clustering rate

Impact of fast ions on density peaking in JET: fluid and gyrokinetic modeling

The effect of fast ions on turbulent particle transport, driven by ion temperature gradient (ITG)/ trapped electron mode turbulence, is studied. Two neutral beam injection (NBI) heated JET discharges in different regimes are analyzed at the radial position ρ$_{t}$=0.6, one of them an L-mode and the other one an H-mode discharge. Results obtained from the computationally efficient fluid model EDWM and the gyro-fluid model TGLF are compared to linear and nonlinear gyrokinetic GENE simulations as well as the experimentally obtained density peaking. In these models, the fast ions are treated as a dynamic species with a Maxwellian background distribution. The dependence of the zero particle flux density gradient (peaking factor) on fast ion density, temperature and corresponding gradients, is investigated. The simulations show that the inclusion of a fast ion species has a stabilizing influence on the ITG mode and reduces the peaking of the main ion and electron density profiles in the absence of sources. The models mostly reproduce the experimentally obtained density peaking for the L-mode discharge whereas the H-mode density peaking is significantly underpredicted, indicating the importance of the NBI particle source for the H-mode density profile

Current Research into Applications of Tomography for Fusion Diagnostics

Retrieving spatial distribution of plasma emissivity from line integrated measurements on tokamaks presents a challenging task due to ill-posedness of the tomography problem and limited number of the lines of sight. Modern methods of plasma tomography therefore implement a-priori information as well as constraints, in particular some form of penalisation of complexity. In this contribution, the current tomography methods under development (Tikhonov regularisation, Bayesian methods and neural networks) are briefly explained taking into account their potential for integration into the fusion reactor diagnostics. In particular, current development of the Minimum Fisher Regularisation method is exemplified with respect to real-time reconstruction capability, combination with spectral unfolding and other prospective tasks