277 research outputs found

    Private Cell Retrieval from Data Warehouses

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    © 2015 IEEE. Publicly accessible data warehouses are an indispensable resource for data analysis. However, they also pose a significant risk to the privacy of the clients, since a data warehouse operator may follow the client's queries and infer what the client is interested in. Private information retrieval (PIR) techniques allow the client to retrieve a cell from a data warehouse without revealing to the operator which cell is retrieved and, therefore, protects the privacy of the client's queries. However, PIR cannot be used to hide online analytical processing (OLAP) operations performed by the client, which may disclose the client's interest. This paper presents a solution for private cell retrieval from a data warehouse on the basis of the Paillier cryptosystem. By our solution, the client can privately perform OLAP operations on the data warehouse and retrieve one (or more) cell without revealing any information about which cell is selected. In addition, we propose a solution for private block download on the basis of the Paillier cryptosystem. Our private block download allows the client to download an encrypted block from a data warehouse without revealing which block in a cloaking region is downloaded and improves the feasibility of our private cell retrieval. Our solutions ensure both the server's privacy and the client's privacy. Our experiments have shown that our solutions are practical

    Macrofauna de invertebrados del Cretácico superior de la Depresión Central Asturiana

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    Se reporta y comenta la fauna de inocerámidos, rudistas, ammonites, braquiópodos y equmnidos recogida y localizada en yacimientos o series estratigráficas de detalle, durante los trabajos de campo de la tesis doctoral del primero de los autores (E.B.) sobre los seláceos del Cretácico de Asturias. La distribución, principalmente de inocerámidos y ammonites, permite identificar el Cenomaniense superior y el Turoniense inferior y medio. Se han reconocido rudistas del Turoniense superior y del Coniaciense, braquiópodos del Cenomaniense y del Santoniense inferior y un registro relativamente rico y variado de equínidos desde el Cenomaniense hasta el Coniaciense.The fauna collected and located on fossil localities or stratigraphical profiles, during the field work of the first author's doctoral thesis on the Cretaceous selachians from Asturias, is reported and commented. It includes inoceramids, rudists, ammonoids, brachiopods and echinoids. Distribution of, mainly inoceramids and ammonoids, allowed to identify the Upper Cenomanian and the Lower and Middle Turonian. LateTuronian and Coniacian rudists have been recognized, as well as Cenomanian and lower Santonian brachiopods and a quite rich and diversified record of echinoids ranging from Cenomanian to Coniacian

    Turismo en espacios rurales: su aplicación en la empresa pecuaria "Bacuranao"

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    The Empresa Pecuaria Bacurailao is localized in the eastern side of the city of Habana in the municipiums of Guanabacoa and Habana del Este. Its milk production has been destined to the city.A group of specialists of our Faculty studied the problems that the enterprise had in relation to the not rentability of the production of Basic Cooperative Unities (U.B.P.C.) in which it is divided.This group tried to look for solutions to this problem without deviation of its principal activity. It was decided then, to study the possibility of applying tourism in rural space as a solution for the existing problem in the enterprise.It was determined the places in which to carry out the touristic activity in the U.B.P.C. A cartographic method was applied that permitted the evaluation of points that could be used as a lookout station to observe rural scenes with some aesthetic value and to establish the use of the areas around so they remain with the fundamental activity that is carried out.La Empresa Pecuaria Bacuranao está localizada al este de la ciudad de La Habana en los municipios de Guanabacoa y Habana del Este. Su producción de leche fresca ha estado destinada al abasto de la Ciudad de La Habana. La Empresa fue objeto de investigación por parte de un equipo de especialistas de nuestra Facultad. Esta investigación detectó diferentes problemas, como los relativos a la no rentabilidad de las Unidades Básicas de Producción Cooperativa (U.B.P.C.) que la componen. Este colectivo se dio a la tarea de buscar soluciones que le permitieran, tanto a la Empresa como a las U.B.P.C., ser rentables sin desviarse de su actividad principal, la producción láctea. Por ello se decide estudiar la posibilidad de aplicación del Turismo en Espacios Rurales como una solución para la problemática existente en laEmpresa. Se determinaron los lugares donde se pudiera realizar la actividad turística en las U.B.P.C. Se aplicó un método cartográfico que permitió evaluar puntos como posibles miradores de conjuntos escénicos rurales con algún valor estético y establecer la propuesta de utilización de las áreas alrededor de los mismos, de modo que queden insertados dentro de la actividad fundamental que allí se realice

    Identifying Human Disease Genes through Cross-Species Gene Mapping of Evolutionary Conserved Processes

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    Understanding complex networks that modulate development in humans is hampered by genetic and phenotypic heterogeneity within and between populations. Here we present a method that exploits natural variation in highly diverse mouse genetic reference panels in which genetic and environmental factors can be tightly controlled. The aim of our study is to test a cross-species genetic mapping strategy, which compares data of gene mapping in human patients with functional data obtained by QTL mapping in recombinant inbred mouse strains in order to prioritize human disease candidate genes.We exploit evolutionary conservation of developmental phenotypes to discover gene variants that influence brain development in humans. We studied corpus callosum volume in a recombinant inbred mouse panel (C57BL/6J×DBA/2J, BXD strains) using high-field strength MRI technology. We aligned mouse mapping results for this neuro-anatomical phenotype with genetic data from patients with abnormal corpus callosum (ACC) development.).This approach that exploits highly diverse mouse strains provides an efficient and effective translational bridge to study the etiology of human developmental disorders, such as autism and schizophrenia

    Role of Plant-Specific N-Terminal Domain of Maize CK2β1 Subunit in CK2β Functions and Holoenzyme Regulation

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    Protein kinase CK2 is a highly pleiotropic Ser/Thr kinase ubiquituous in eukaryotic organisms. CK2 is organized as a heterotetrameric enzyme composed of two types of subunits: the catalytic (CK2α) and the regulatory (CK2β). The CK2β subunits enhance the stability, activity and specificity of the holoenzyme, but they can also perform functions independently of the CK2 tetramer. CK2β regulatory subunits in plants differ from their animal or yeast counterparts, since they present an additional specific N-terminal extension of about 90 aminoacids that shares no homology with any previously characterized functional domain. Sequence analysis of the N-terminal domain of land plant CK2β subunit sequences reveals its arrangement through short, conserved motifs, some of them including CK2 autophosphorylation sites. By using maize CK2β1 and a deleted version (ΔNCK2β1) lacking the N-terminal domain, we have demonstrated that CK2β1 is autophosphorylated within the N-terminal domain. Moreover, the holoenzyme composed with CK2α1/ΔNCK2β1 is able to phosphorylate different substrates more efficiently than CK2α1/CK2β1 or CK2α alone. Transient overexpression of CK2β1 and ΔNCK2β1 fused to GFP in different plant systems show that the presence of N-terminal domain enhances aggregation in nuclear speckles and stabilizes the protein against proteasome degradation. Finally, bimolecular fluorescence complementation (BiFC) assays show the nuclear and cytoplasmic location of the plant CK2 holoenzyme, in contrast to the individual CK2α/β subunits mainly observed in the nucleus. All together, our results support the hypothesis that the plant-specific N-terminal domain of CK2β subunits is involved in the down-regulation of the CK2 holoenzyme activity and in the stabilization of CK2β1 protein. In summary, the whole amount of data shown in this work suggests that this domain was acquired by plants for regulatory purposes
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