Reestructuración del proceso de desarrollo de productos de la empresa ARBORIT S.A.

El presente proyecto de grado de Ingeniería de Diseño de Producto de la Universidad EAFIT se realizó con el fin de reestructurar el proceso de desarrollo de productos de la empresa ARBORIT S.A. Dicha propuesta se llevó a cabo principalmente utilizando la herramienta de diagnóstico proporcionada por el grupo de investigación GRID de Ingeniería de Diseño de Producto de la universidad EAFIT, y los modelos de desarrollo de nuevos productos presentados por los siguientes autores, así: Karl T. Ulrich y Steven D. Eppinger: Proceso de desarrollo del producto, Mike Baxter: Risk Management Funnel, G. Pahl y W. Beitz: Proceso de Diseño, Jan Buijs – TUDelft: Circular Chaos.x, 96 p., + anexosContenido parcial: Alcance del proyecto y productos -- Análisis de la empresa -- Planteamiento de la estrategia -- Norma de calidad ISO 9001 -- Desarrollo de la línea de mobiliario infantil para juego y estudio ARBORIT S.A

Ecology of Anopheles (Nyssorhynchus) darlingi Root in the installation area of a hydroelectric scheme on the border between the States of Mato Grosso do Sul and São Paulo

INTRODUÇÃO: Hidrelétricas alteram o fluxo das águas e provocam impactos sobre a composição de mosquitos, justificando-se essa pesquisa. O objetivo da pesquisa foi estudar anofelinos de área sob a influência de um novo lago e avaliar a vulnerabilidade relativa à malária. MÉTODOS: Foram feitas coletas de Anopheles nas margens da Represa Porto Primavera, durante as fases do alagamento até sua cota máxima. Utilizaram-se as técnicas: atrativa humana, de armadilha de Shannon e concha entomológica. Os indicadores Riqueza e Diversidade foram utilizados para medir o impacto. A análise das distribuições temporais foi realizada pelo teste Mann-Whitney, considerando localidade, cota e método de captura como variáveis independentes (α=0,05). RESULTADOS: A densidade de Anopheles darlingi oscilou entre as localidades A, B e C, sendo que os maiores picos foram para B e C. Com a estabilidade do lago, no último nível, evidenciou-se a tendência de redução da densidade de Anopheles darlingi. CONCLUSÕES: Sugere-se que o risco de autoctonia de malária nas proximidades do lago permanece inalterado, ficando o alerta para esporádicas infecções humanas.IINTRODUCTION: Hydroelectric schemes modify the water flow and cause an impact on mosquito composition, thus justifying investigations. The aim of this study was to study anophelines in the area under the influence of a new lake and to evaluate their relative vulnerability to malaria. METHODS: Anopheles specimens were collected from the edges of the Porto Primavera reservoir, during the phases of reservoir filling until its maximum level was reached. The techniques used were attraction to humans, Shannon traps and entomological scoops. The richness and diversity indexes were used to measure the impact. The temporal distribution analysis was performed using the Mann-Whitney test, taking the site, level and capture method as independent variables (α = 0.05). RESULTS: The density of Anopheles darlingi oscillated among the sites A, B and C, and the biggest peaks were located at B and C. After the lake reached its stable maximum level, there was a tendency for the density to decrease. CONCLUSIONS: It is suggested that the risk of autochthonous malaria in the vicinity of the lake remained unchanged, but it is necessary to remain alert regarding sporadic human infections.Brasil - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Integrated analysis of Wnt signalling system component gene expression

Wnt signalling controls patterning and differentiation across many tissues and organs of the developing embryo through temporally and spatially restricted expression of multi-gene families encoding ligands, receptors, pathway modulators and intracellular components. Here, we report an integrated analysis of key genes in the 3D space of the mouse embryo across multiple stages of development. We applied a method for 3D/3D image transformation to map all gene expression patterns to a single reference embryo for each stage, providing both visual analysis and volumetric mapping allowing computational methods to interrogate the combined expression patterns. We identify territories where multiple Wnt and Fzd genes are co-expressed and cross-compare all patterns, including all seven Wnt paralogous gene pairs. The comprehensive analysis revealed regions in the embryo where no Wnt or Fzd gene expression is detected, and where single Wnt genes are uniquely expressed. This work provides insight into a previously unappreciated level of organisation of expression patterns, as well as presenting a resource that can be utilised further by the research community for whole-system analysis

The Impact of Name-Matching and Blocking on Author Disambiguation

In this work, we address the problem of blocking in the context of author name disambiguation. We describe a framework that formalizes different ways of name-matching to determine which names could potentially refer to the same author. We focus on name variations that follow from specifying a name with different completeness (i.e. full first name or only initial). We extend this framework by a simple way to define traditional, new and custom blocking schemes. Then, we evaluate different old and new schemes in the Web of Science. In this context we define and compare a new type of blocking schemes. Based on these results, we discuss the question whether name-matching can be used in blocking evaluation as a replacement of annotated author identifiers. Finally, we argue that blocking can have a strong impact on the application and evaluation of author disambiguation

Efeitos do alagamento do Rio Paraná na atividade horária de Anopheles (Nyssorhynchus) darlingi Root (Diptera: Culicidae), na divisa dos estados do Mato Grosso do Sul e São Paulo, Brasil

INTRODUCTION: Study of the temporal activity of malaria vectors during the implantation of a hydroelectric power station on the River Paraná, intended to generate electrical energy. The river separates the States of São Paulo and Mato Grosso do Sul, in Brazil. The objective was to verify whether alterations occurred in the wealth and diversity indices of Anopheles, following two successive floods, extended to the temporal activity and nycthemeral rhythm followed over a five year period. METHODS: Mosquito capture was performed monthly using the Human Attraction Technique and Shannon Traps. The first, executed for 24h, provided the nycthemeral rhythm and the second, lasting 15h, permitted the tracking of Anopheles during the two floods. RESULTS: The bimodal pattern of Anopheles darlingi defined before these floods was modified throughout the environment interventions. The same effect had repercussions on the populations of An albitarsis s.l., An triannulatus and An galvaoi. Activity prior to twilight was less affected by the environment alterations. CONCLUSIONS: The dam construction provoked changes in Anopheles temporal activity patterns, permitting classification of the area as an ecologically steady and unstable situation. Differences observed in Anopheles behavior due to the capture methods revealed the influence of solo and multiple attractiveness inside the populations studied.INTRODUÇÃO: Estudo da atividade horária de vetores da malária durante a implantação de uma represa no Rio Paraná, destinada à geração de energia elétrica. O rio separa os Estados de São Paulo e Mato Grosso do Sul, no Brasil. O objetivo foi verificar se as alterações na riqueza e diversidades de Anopheles diante de duas inundações sucessivas se estendiam à atividade horária e ritmo nictimeral numa série temporal de cinco anos. MÉTODOS: A captura de mosquito foi mensal, por meio dos métodos Técnica Atrativa Humana e Armadilha de Shannon. A primeira, executada durante 24 horas, forneceu o ritmo nictimeral e a segunda, com duração de 15 horas, para acompanhar os anofelinos durante as duas inundações. RESULTADOS: O padrão bimodal de Anopheles darlingi definido antes dessas inundações foi alterado ao longo das intervenções ambientais. O mesmo efeito repercutiu nas populações de An albitarsis s.l., An triannulatus e An galvaoi. A atividade pré-crepuscular foi a menos afetada pelas alterações ambientais. CONCLUSÕES: As barragens provocam mudanças no padrão de atividade horária dos anofelinos permitindo classificar a área em situação ecologicamente estável e instável. Diferenças observadas no comportamento dos anofelinos pelos métodos de captura mostram a influência da uni e múltipla atratividade dentro das populações estudadas.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Companhia Energética de São Paul

A relevância da avaliação para o investimento social privado

O crescente interesse pelo uso estratégico da avaliação de programas e políticas sociais no Brasil tem sido marcado por avanços, mas também por inquietações entre formuladores, gestores e avaliadores sobre suas escolhas metodológicas. Qual método é mais adequado para avaliar este ou aquele programa? Qual abordagem é mais precisa? Que método é mais sensível à realidade social? Que percurso avaliativo é capaz de exercer maior influência sobre a tomada de decisões? Lançando mão de reflexões teórica e casos práticos, somando experiências estrangeiras e brasileiras, o livro oferece respostas a estas perguntas, capazes de alavancar a capacidade de escolher métodos que melhor dialoguem com a realidade social, bem como com suas próprias premissas éticas, políticas e técnicas. Fruto do II Seminário Internacional "A Relevância da Avaliação para o Investimento Social Privado: Metodologias", iniciativa da Fundação Itaú Social, Fundação Roberto Marinho, Fundação Maria Cecília Souto Vidigal em parceria com a Move e apoio do GIFE e da Fundação Santillana, esta publicação é mais uma contribuição para o plural e, cada vez mais consistente, campo avaliativo do País

Cryptic kin discrimination during communal lactation in mice favours cooperation between relatives

Breeding females can cooperate by rearing their offspring communally, sharing synergistic benefits of offspring care but risking exploitation by partners. In lactating mammals, communal rearing occurs mostly among close relatives. Inclusive fitness theory predicts enhanced cooperation between related partners and greater willingness to compensate for any partner under-investment, while females are less likely to bias investment towards own offspring. We use a dual isotopic tracer approach to track individual milk allocation when familiar pairs of sisters or unrelated house mice reared offspring communally. Closely related pairs show lower energy demand and pups experience better access to non-maternal milk. Lactational investment is more skewed between sister partners but females pay greater energetic costs per own offspring reared with an unrelated partner. The choice of close kin as cooperative partners is strongly favoured by these direct as well as indirect benefits, providing a driver to maintain female kin groups for communal breeding

Students’ perception of campus sustainability in a Brazilian university

Over recent decades, higher education institutions (HEIs) have been recognised as ideal leaders in supporting the transition to sustainable societies. Leading by example, they have been embarking upon committing themselves to sustainability by incorporating sustainable development practices (SDP) into their integrated management system. As a major stakeholders group, students play a significant role in moving this agenda forward. This study aims to develop an assessment framework to evaluate the students’ perception of campus sustainability, based on a Brazilian HEI case study. A survey was assembled using five demographic questions, three dichotomous questions, and 43 items resorting to a 1–5 Likert scale and administered to a sample of 207 undergraduate technology students. Through exploratory and confirmatory factor analysis, a reliable scale emerges with 31 items grouped into eight dimensions: Waste; Emissions/Procurement; Energy; Quality of Life in the Workplace (QLW); Fauna and Flora; Institutional Framework; Education/Research; and, Water. The dimensions explain 68.50% of the total model variance. The lowest-evaluated dimension was Emissions/Procurement, with a 2.26 average value, followed by water (2.27) and Energy (2.28); all three of these were below the scale’s midpoint. The best-evaluated dimension was Education/Research, with an average of 3.30. This research provides an insight into HEI students’ sustainability perception and into how the university decision-makers could improve the sustainable practices to increase the students’ engagement.- (undefined

Duration of larval and pupal development stages of Aedes albopictus in natural and artificial containers

Aedes albopictus were reared in different containers: a tree hole, a bamboo stump and an auto tire. The total times from egg hatching to adult emergence were of 19.6,27.3 and 37.5 days, respectively, according to the container. The first, second and third-instar larvae presented growth periods with highly similar durations. The fourth-instar larvae was longer than the others stages. The pupation time was longer than the fourth-instar larvae growth period. The temperature of the breeding sites studied, which was of 18&deg; C to 22&deg; C on average, was also taken into consideration. The mortality of the immature stages was analysed and compared as between the experimental groups; it was lower in the natural containers than in the discarded tire. The average wing length of adult females emerging from tree hole was significantly larger (p < 0.05) than that of those emerging from the tire.Ae. albopictus foi criado em oco de árvore, internódio de bambu e pneu de carro descartável, sob condições de campo. O resultado obtido a partir de larvas recém-nascidas até alado foi de 19,6,27,3 e 37,5 dias. As larvas dos três primeiros estádios tiveram tempo de crescimento similar, não obstante tratar-se de diferentes micro-habitats estudados. Contudo, larvas de 4º estádio apresentaram tempo de duração mais longo e crescente do oco de árvore para o pneu. A temperatura média dos três micro-habitats variou de 18&deg; Ca 22&deg; C. O resultado da taxa de mortalidade encontrada foi menor para larva e pupa do oco de árvore e maior para o pneu. A medida do comprimento médio de asa das fêmeas emergidas do oco de árvore foi maior em relação àquela do pneu

An agenda for future research regarding the mental health of young people with care experience

Young people who are currently or were previously in state care have consistently been found to have much higher rates of mental health and neurodevelopmental difficulties than the general youth population. While a number of high-quality reviews highlight what research has been undertaken in relation to the mental health of young people with care experience and the gaps in our knowledge and understanding, there is, until now, no consensus, so far as we aware, as to where our collective research efforts should be directed with this important group. Through a series of UK wide workshops, we undertook a consultative process to identify an agreed research agenda between those with lived experience of being in care (n = 15), practitioners, policy makers and researchers (n = 59), for future research regarding the mental health of young people with care experience, including those who are neurodiverse/have a neurodevelopmental difficulty. This consensus statement identified 21 foci within four broad categories: how we conceptualize mental health; under-studied populations; under-studied topics; and underused methodologies. We hope that those who commission, fund and undertake research will engage in this discussion about the future agenda for research regarding the mental health of young people with care experience