On black hole thermalization, D0 brane dynamics, and emergent spacetime

When matter falls past the horizon of a large black hole, the expectation from string theory is that the configuration thermalizes and the information in the probe is rather quickly scrambled away. The traditional view of a classical unique spacetime near a black hole horizon conflicts with this picture. The question then arises as to what spacetime does the probe actually see as it crosses a horizon, and how does the background geometry imprint its signature onto the thermal properties of the probe. In this work, we explore these questions through an extensive series of numerical simulations of D0 branes. We determine that the D0 branes quickly settle into an incompressible symmetric state -- thermalized within a few oscillations through a process driven entirely by internal non-linear dynamics. Surprisingly, thermal background fluctuations play no role in this mechanism. Signatures of the background fields in this thermal state arise either through fluxes, i.e. black hole hair; or if the probe expands to the size of the horizon -- which we see evidence of. We determine simple scaling relations for the D0 branes' equilibrium size, time to thermalize, lifetime, and temperature in terms of their number, initial energy, and the background fields. Our results are consistent with the conjecture that black holes are the fastest scramblers as seen by Matrix theory.Comment: 43 pages, 12 figures; v2: added analysis showing that results are consistent with and confirm Susskind conjecture on black hole thermalization. Added clarification about strong coupling regime. Citation adde

Toric Symmetry Of CP3

We exhaustively analyze the toric symmetries of CP^3 and its toric blowups. Our motivation is to study toric symmetry as a computational technique in Gromov-Witten theory and Donaldson-Thomas theory. We identify all nontrivial toric symmetries. The induced nontrivial isomorphisms lift and provide new symmetries at the level of Gromov-Witten Theory and Donaldson-Thomas Theory. The polytopes of the toric varieties in question include the permutohedron, the cyclohedron, the associahedron, and in fact all graph associahedra, among others

Generation of a non-small cell lung cancer transcriptome microarray

<p>Abstract</p> <p>Background</p> <p>Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide. At present no reliable biomarkers are available to guide the management of this condition. Microarray technology may allow appropriate biomarkers to be identified but present platforms are lacking disease focus and are thus likely to miss potentially vital information contained in patient tissue samples.</p> <p>Methods</p> <p>A combination of large-scale in-house sequencing, gene expression profiling and public sequence and gene expression data mining were used to characterise the transcriptome of NSCLC and the data used to generate a disease-focused microarray – the Lung Cancer DSA research tool.</p> <p>Results</p> <p>Built on the Affymetrix GeneChip platform, the Lung Cancer DSA research tool allows for interrogation of ~60,000 transcripts relevant to Lung Cancer, tens of thousands of which are unavailable on leading commercial microarrays.</p> <p>Conclusion</p> <p>We have developed the first high-density disease specific transcriptome microarray. We present the array design process and the results of experiments carried out to demonstrate the array's utility. This approach serves as a template for the development of other disease transcriptome microarrays, including non-neoplastic diseases.</p

Sketching women in court: The visual construction of co-accused women in court drawings

This paper explores the visual construction and representation of co-accused women offenders in court drawings. It utilises three case studies of female co-defendants who appeared in the England and Wales court system between 2003 and 2013. In doing so this paper falls into three parts. The first part considers the emergence of the sub-discipline, visual criminology and examines what is known about the visual representation of female offenders. The second part presents the findings of an empirical investigation, which involved engaging in a critical, reflexive visual analysis of a selection of court drawings of three female co-offenders. The third part discusses the ways in which the court artists' interpretation, the conventions of court sketching, and motifs of female offenders as secondary actors, drew on existing myths and prejudices by representing the women as listening, remorseless ‘others’