Design, performance, and applications of a coherent ultra-wideband random noise radar

A novel coherent ultra-wideband radar system operating in the 1- to 2-GHz frequency range has been developed recently at the University of Nebraska. The radar system transmits white Gaussian noise. Detection and localization of buried objects is accomplished by correlating the reflected waveform with a time-delayed replica of the transmitted waveform. Broadband dual-polarized log-periodic antennas are used for transmission and reception. A unique signal-processing scheme is used to inject coherence into the system by frequency translation of the ultrawideband signal by a coherent 160-MHz phase-locked source prior to performing heterodyne correlation. The system coherence allows the extraction of a target’s polarimetric amplitude and phase characteristics. This paper describes the unique design features of the radar system, develops the theoretical foundations of noise polarimetry, provides experimental evidence of the polarimetric and resolution capabilities of the system, and demonstrates results obtained in subsurface probing applications

High temperature braided rope seals for static sealing applications

Achieving efficiency and performance goals of advanced aircraft and industrial systems are leading designers to implement high temperature materials such as ceramics and intermetallics. Generally these advanced materials are applied selectively in the highest temperature sections of the engine system including the combustor and high pressure turbine, amongst others. Thermal strains that result in attaching the low expansion-rate components to high expansion rate superalloy structures can cause significant life reduction in the components. Seals are being designed to both seal and to serve as compliant mounts allowing for relative thermal growths between high temperature but brittle primary structures and the surrounding support structures. Designers require high temperature, low-leakage, compliant seals to mitigate thermal stresses and control parasitic and cooling airflow between structures. NASA is developing high temperature braided rope seals in a variety of configurations to help solve these problems. This paper will describe the types of seals being developed, describe unique test techniques used to assess seal performance, and present leakage flow data under representative pressure, temperature and scrubbing conditions. Feasibility of the braided rope seals for both an industrial tube seal and a turbine vane seal application is also demonstrated

Spatially heterogeneous land cover/land use and climatic risk factors of tick-borne feline cytauxzoonosis

Background: Feline cytauxzoonosis is a highly fatal tick-borne disease caused by a hemoparasitic protozoan, Cytauxzoon felis. This disease is a leading cause of mortality for cats in the Midwestern United States, and no vaccine or effective treatment options exist. Prevention based on knowledge of risk factors is therefore vital. Associations of different environmental factors, including recent climate were evaluated as potential risk factors for cytauxzoonosis using Geographic Information Systems (GIS). Methods: There were 69 cases determined to be positive for cytauxzoonosis based upon positive identification of C. felis within blood film examinations, tissue impression smears, or histopathologic examination of tissues. Negative controls totaling 123 were selected from feline cases that had a history of fever, malaise, icterus, and anorexia but lack of C. felis within blood films, impression smears, or histopathologic examination of tissues. Additional criteria to rule out C. felis among controls were the presence of regenerative anemia, cytologic examination of blood marrow or lymph node aspirate, other causative agent diagnosed, or survival of 25 days or greater after testing. Potential environmental determinants were derived from publicly available sources, viz., US Department of Agriculture (soil attributes), US Geological Survey (land-cover/landscape, landscape metrics), and NASA (climate). Candidate variables were screened using univariate logistic models with a liberal p value (0.2), and associations with cytauxzoonosis were modeled using a global multivariate logistic model (p<0.05). Spatial heterogeneity among significant variables in the study region was modeled using a geographically weighted regression (GWR) approach. Results: Total Edge Contrast Index (TECI), grassland-coverage, humidity conditions recorded during the 9th week prior to case arrival, and an interaction variable, “diurnal temperature range×percent mixed forest area” were significant risk factors for cytauxzoonosis in the study region. TECI and grassland areas exhibited significant regional differences in their effects on cytauxzoonosis outcome, whereas others were uniform. Conclusions: Land-cover areas favorable for tick habitats and climatic conditions that favor the tick life cycle are strong risk factors for feline cytauxzoonosis. Spatial heterogeneity and interaction effects between land-cover and climatic variables may reveal new information when evaluating risk factors for vector-borne diseases

Quasi periodic oscillations in XTE J0111.2--7317, highest frequency among the HMXB pulsars

We report here discovery of Quasi Periodic Oscillations (QPOs) in the High Mass X-ray Binary (HMXB) Pulsar XTE J0111.20-7317 during a transient outburst in this source in December 1998. Using observations made with the proportional counter array of the Rossi X-ray Timing Explorer during the second peak and the declining phase of this outburst we have discovered a QPO feature at a frequency of 1.27 Hz. We have ruled out the possibility that the observed QPOs can instead be from the neighbouring bright X-ray pulsar SMC X-1. This is the highest frequency QPO feature ever detected in any HMXB pulsar. In the absence of a cyclotron absorption feature in the X-ray spectrum, the QPO feature, along with the pulse period and X-ray flux measurement measurement helps us to constrain the magnetic field strength of the neutron star.Comment: Accepted for publication in The Astrophysical Journa

Early inflammatory markers as prognostic indicators following allogeneic stem cell transplantation

Allogeneic stem cell transplantation is used widely in the treatment of hematopoietic malignancy although graft versus host disease and relapse remain major complications. We measured the serum protein expression of 92 inflammation-related markers from 49 patients at Day 0 (D0) and 154 patients at Day 14 (D14) following transplantation and related values to subsequent clinical outcomes. Low levels of 7 proteins at D0 were linked to GvHD whilst high levels of 7 proteins were associated with relapse. The concentration of 38 proteins increased over 14 days and higher inflammatory response at D14 was strongly correlated with patient age. A marked increment in protein concentration during this period associated with GvHD but reduced risk of disease relapse, indicating a link with alloreactive immunity. In contrast, patients who demonstrated low dynamic elevation of inflammatory markers during the first 14 days were at increased risk of subsequent disease relapse. Multivariate time-to-event analysis revealed that high CCL23 at D14 was associative of AGvHD, CXCL10 with reduced rate of relapse, and high PD-L1 with reduced overall survival. This work identifies a dynamic pattern of inflammatory biomarkers in the very early post-transplantation period and reveals early protein markers that may help to guide patient management.</p

Subglacial Lake Vostok (Antarctica) Accretion Ice Contains a Diverse Set of Sequences from Aquatic, Marine and Sediment-Inhabiting Bacteria and Eukarya

Lake Vostok, the 7th largest (by volume) and 4th deepest lake on Earth, is covered by more than 3,700 m of ice, making it the largest subglacial lake known. The combination of cold, heat (from possible hydrothermal activity), pressure (from the overriding glacier), limited nutrients and complete darkness presents extreme challenges to life. Here, we report metagenomic/metatranscriptomic sequence analyses from four accretion ice sections from the Vostok 5G ice core. Two sections accreted in the vicinity of an embayment on the southwestern end of the lake, and the other two represented part of the southern main basin. We obtained 3,507 unique gene sequences from concentrates of 500 ml of 0.22 μm-filtered accretion ice meltwater. Taxonomic classifications (to genus and/or species) were possible for 1,623 of the sequences. Species determinations in combination with mRNA gene sequence results allowed deduction of the metabolic pathways represented in the accretion ice and, by extension, in the lake. Approximately 94% of the sequences were from Bacteria and 6% were from Eukarya. Only two sequences were from Archaea. In general, the taxa were similar to organisms previously described from lakes, brackish water, marine environments, soil, glaciers, ice, lake sediments, deep-sea sediments, deep-sea thermal vents, animals and plants. Sequences from aerobic, anaerobic, psychrophilic, thermophilic, halophilic, alkaliphilic, acidophilic, desiccation-resistant, autotrophic and heterotrophic organisms were present, including a number from multicellular eukaryotes. © 2013 Shtarkman et al

Microbial energy and matter transformation in agricultural soils

Low bioavailability of organic carbon (C) and energy are key constraints to microbial biomass and activity. Microbial biomass, biodiversity and activity are all involved in regulating soil ecosystem services such as plant productivity, nutrient cycling and greenhouse gas emissions. A number of agricultural practices, of which tillage and fertiliser application are two examples, can increase the availability of soil organic C (SOC). Such practices often lead to reductions in soil aggregation and increases in SOC loss and greenhouse gas emissions. This review focuses on how the bioavailability of SOC and energy influence the ecology and functioning of microorganisms in agricultural soils. Firstly we consider how management practices affect the bioavailability of SOC and energy at the ecosystem level. Secondly we consider the interaction between SOC bioavailability and ecological principles that shape microbial community composition and function in agricultural systems. Lastly, we discuss and compare several examples of physiological differences that underlie how microbial species respond to C availability and management practices. We present evidence whereby management practices that increase the bioavailability of SOC alter community structure and function to favour microbial species likely to be associated with increased rates of SOC loss compared to natural ecosystems. We argue that efforts to restore stabilised, sequestered SOC stocks and improve ecosystem services in agricultural systems should be directed toward the manipulation of the microbial community composition and function to favour species associated with reduced rates of SOC loss. We conclude with several suggestions regarding where improvements in multi-disciplinary approaches concerning soil microbiology can be made to improve the sustainability of agricultural systems

Fermi surface mapping and the nature of charge density wave order in the kagome superconductor CsV3_3Sb5_5

The recently discovered family of AV$_3$Sb$_5$ (A: K, Rb Cs) kagome metals possess a unique combination of nontrivial band topology, superconducting ground states, and signatures of electron correlations manifest via competing charge density wave order. Little is understood regarding the nature of the charge density wave (CDW) instability inherent to these compounds and the potential correlation with the accompanying onset of a large anomalous Hall response. To understand the impact of the CDW order on the electronic structure in these systems, we present quantum oscillation measurements on single crystals of CsV$_3$Sb$_5$. Our data provides direct evidence that the CDW invokes a substantial reconstruction of the Fermi surface pockets associated with the vanadium orbitals and the kagome lattice framework. In conjunction with density functional theory modeling, we are able to identify split oscillation frequencies originating from reconstructed pockets built from vanadium orbitals and Dirac-like bands. Complementary diffraction measurements are further able to demonstrate that the CDW instability has a correlated phasing between neighboring V$_3$Sb$_5$ planes. These results provide critical insights into the underlying CDW instability in AV$_3$Sb$_5$ kagome metals and support minimal models of CDW order arising from within the vanadium-based kagome lattice.Comment: 12 pages, 9 figure