105 research outputs found

    Recent geophysical survey of English monastic sites

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    Geophysical survey can provide additional detail even from well understood monastic sites. Extended landscape survey in rural settings can reveal wider semi-industrial monastic activity. Vehicle towed ground penetrating radar used to complement earth resistance and magnetic survey

    Fore! GPR survey of the Belhus Tudor water gardens

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    Covid-19 restrictions allowed unique access to this site on a temporarily closed golf course. Vehicle towed ground penetrating radar survey provided rapid coverage of the site. Geophysical survey helped support local volunteer research groups. Significant remains survive despite demolition of the Tudor mansion and landscaping for the golf-course. Detailed topographic data was generated from UAV based photography through Structure from Motion

    Stepped frequency GPR survey with a multi-element array antenna: Results from field application on archaeological sites

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    The value of large scale GPR surveys to landscape archaeology is becoming increasingly important (e.g. Nishimura and Goodman, 2000; Neubauer et al., 2002; Leckebusch, 2003; Linford, 2004). However, the use of conventional single channel instrumentation requires either a significant investment of time for data acquisition or a compromise between sampling methodology and the area of coverage. The recent development of multi-channel, vehicle towed GPR arrays offers the potential to obtain very d..

    FAK Promotes Osteoblast Progenitor Cell Proliferation and Differentiation by Enhancing Wnt Signaling

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    Decreased bone formation is often associated with increased bone marrow adiposity. The molecular mechanisms that are accountable for the negative correlation between bone mass and bone marrow adiposity are incompletely understood. Focal adhesion kinase (FAK) has critical functions in proliferation and differentiation of many cell types; however, its roles in osteoblast lineage cells are largely unknown. We show herein that mice lacking FAK in Osterixâ expressing cells exhibited decreased osteoblast number and low bone mass as well as increased bone marrow adiposity. The decreased bone mass in FAKâ deficient mice was accounted for by decreased proliferation, compromised osteogenic differentiation, and increased adipogenic differentiation of bone marrow Osterixâ expressing cells resulting from downregulation of Wnt/βâ catenin signaling due to the reduced expression of canonical Wnt ligands. In contrast, FAK loss in calvarial preosteoblasts had no adverse effect on their proliferation and osteogenic differentiation and these cells had intact Wnt/βâ catenin signaling. © 2016 American Society for Bone and Mineral Research.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135488/1/jbmr2908_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/135488/2/jbmr2908-sup-0001-SuppData-S1.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/135488/3/jbmr2908.pd

    CPT1a-dependent long-chain fatty acid oxidation is essential for maintaining glucagon secretion from pancreatic islets

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    Glucagon, the principal hyperglycemic hormone, is secreted from pancreatic islet Îą cells as part of the counter-regulatory response to hypoglycemia. Hence, secretory output from Îą cells is under high demand in conditions of low glucose supply. Many tissues oxidize fat as an alternate energy substrate. Here, we show that glucagon secretion in low glucose conditions is maintained by fatty acid metabolism in both mouse and human islets, and that inhibiting this metabolic pathway profoundly decreases glucagon output by depolarizing Îą cell membrane potential and decreasing action potential amplitude. We demonstrate, by using experimental and computational approaches, that this is not mediated by the KATP channel, but instead due to reduced operation of the Na+-K+ pump. These data suggest that counter-regulatory secretion of glucagon is driven by fatty acid metabolism, and that the Na+-K+ pump is an important ATP-dependent regulator of Îą cell function

    VLA/Realfast Detection of a Burst from FRB 180916.J0158+65 and Tests for Periodic Activity

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    We report on the detection of a burst from FRB 180916 by realfast/Very Large Array and present software for interpreting fast radio bursts (FRB) periodicity. We demonstrate a range of periodicity analyses with bursts from FRB 180916, FRB 121102 and FRB 180814. Our results for FRB 180916 and FRB 121102 are consistent with published results. For FRB 180814, we did not detect any significant periodic episodes. The realfast-detected and other high-frequency bursts for FRB 180916 tend to lie at the beginning of the activity window, indicating a possible phase-frequency relation. The python package frbpa can be used to reproduce and expand on this analysis to test models for repeating FRBs

    VLA/Realfast Detection of a Burst from FRB180916.J0158+65 and Tests for Periodic Activity

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    We report on the detection of a burst from FRB180916 by realfast/VLA and present software for interpreting fast radio bursts (FRB) periodicity. We demonstrate a range of periodicity analyses with bursts from FRB180916, FRB121102 and FRB180814. Our results for FRB180916 and FRB121102 are consistent with published results. For FRB180814, we did not detect any significant periodic episodes. The realfast-detected and other high-frequency bursts for FRB180916 tend to lie at the beginning of the activity window, indicating a possible phase-frequency relation. The python package frbpa\texttt{frbpa} can be used to reproduce and expand on this analysis to test models for repeating FRBs.Comment: Published in Research Notes of the AA

    The Ursinus Weekly, May 7, 1951

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    Bill LeKernec to edit next year\u27s Lantern • Sororities elect new officers, plan events • Varsity banquet tonight • W. A. A. holds election • Y members plan 1951-52 activities at camp retreat • Campus ready for May Day; Pageant, play to be big events • Professors tackle broad questions in first panel • YM-YW name cabinet, heads of commission • Graduation announcements available to seniors • Students cast primary votes for officers • Election of Curtain Club officers listed • Chi Alpha to elect • Editorials: System a success • Making of foreign policy • Letters to the editor • Three officials embroiled • Ursinus mentioned in Gramercy Ghost • May Day histories reveal variety of festivities • Weekly scribe sheds light on life of famous Ursinus College athlete • Local lassies win 4-1 over Rosemont • Interfraternity track meet to begin this Wednesday • Temple women defeat local tennis squad on May 2 • Cindermen win as Eshbach, Scheirer and Loomis are double winners • Bears capitalize on four hits to beat Garnet • Moravian, Elizabethtown suffer as netmen extend streak to four • Ursinus enters three in intercollege tennis • Bearettes shut-out Albright squad • Lincoln nine halts rally to defeat Grizzlies, 6 to 3 • Curtis clinches first place slots in both leagues • Women\u27s softball team defeats Drexel, Temple • Forum speaker tells of Turkey\u27s position • Dr. Rice invited to Washington for Atlantic Union Conference • Ann Knaur elected President of French Club • Rec center party planned • Women day students hold senior dinner • Supper tickets on sale • Chess Club ends successful season • Shaw named prexyhttps://digitalcommons.ursinus.edu/weekly/1568/thumbnail.jp
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