451 research outputs found

    Chicken Paprika and Tug of War: the Romantic Dream Song 4 by John Berryman

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    Helen Vendler argues that John Berryman’s The Dream Songs synthesizes the Freudian Id and the Christian Conscience as personified by Henry and Mr. Bones respectively. Through a close reading, this essay seeks to analyze Vendler’s claim specifically within “Dream Song 4”, in which, the poet utilizes a trope from American minstrelsy to depict the lustful thoughts of a man, presumably Berryman himself, dining at an upscale restaurant. The two speakers of the poem personify and divide his mind and in keeping with the vaudeville performances Berryman draws from, Henry behaves with erratic irrationality, curbed only by the reason of his counterpart. Because Mr. Bones exhibits a sense of contempt for the Id, a departure from the neutrality of the Conscience, I conclude the Superego is present, contrary to Vendler’s claim. Throughout, the essay I discuss the implications of a Freudian mind absent the Ego as a condition integral for society’s continuance and as an honest portrayal of the private thoughts taking place within. The poem’s eighteen-line style alludes to the Petrarchan sonnet and a romance impeded. But Berryman’s modernized version reinterprets love to be something as meaningless and instinctual as lusting after a married woman nearby yet so powerful as it induces thoughts of diving upon her. “Dream Song 4” Uncovers the human mind to its most unadulterated form, unobstructed by lofty notions of romance or even one’s own identity. What remains is the drama of the Id and Superego in tug of war while a man silently eats his spumoni at a restaurant

    Off the rails: understanding the derailment of a lean manufacturing initiative

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    This study focuses on why lean manufacturing change initiatives at a Northern New England company failed to produce sustained results. Consultants and leaders share responsibility for the sustainability of the change initiatives they undertake. Rationally, neither party would undertake a change initiative with the intent to fail, yet clearly, even highly structured and well-tested initiatives often do fail (derail) in practice. This research used an observational methodology to uncover answers to the question, “what are the key factors that can cause the derailment of a well-intended, highly-structured change initiative?” In addition to consistency with findings from other studies on sustaining lean projects, this study further extends those findings and uncovered new variables to consider when implementing lean projects and other structured interventions in general. Based on the results of this study, the authors propose a model of four phases that influence lean project sustainability: foundation, preparation, implementation and sustainability for continuous improvements

    Ray-tracing in four and higher dimensional black holes: An analytical approximation

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    We study null rays propagation in a spacetime of static Schwarzschild--Tangherlini black holes in arbitrary number of dimensions. We focus on the bending angle and the retarded time delay for rays emitted in the vicinity of a black hole and propagating to the infinity. We obtain an analytic expression in terms of elementary functions which approximate the bending angle and time delay in these spacetimes with high accuracy. We analyze the relative error of the developed analytic approximations and show that it is quite small in the complete domain of the parameter space for the rays reaching the infinity and for different number of the spacetime dimensions. Possible applications of the obtained results are briefly discussed.Comment: 12 pages, 11 figures, text added to the figures along the abscissa and ordinate axes, typing errors corrected, some new text added in the main text also. Accepted for publication in Physical Review

    Parallel-propagated frame along null geodesics in higher-dimensional black hole spacetimes

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    In [arXiv:0803.3259] the equations describing the parallel transport of orthonormal frames along timelike (spacelike) geodesics in a spacetime admitting a non-degenerate principal conformal Killing-Yano 2-form h were solved. The construction employed is based on studying the Darboux subspaces of the 2-form F obtained as a projection of h along the geodesic trajectory. In this paper we demonstrate that, although slightly modified, a similar construction is possible also in the case of null geodesics. In particular, we explicitly construct the parallel-transported frames along null geodesics in D=4,5,6 Kerr-NUT-(A)dS spacetimes. We further discuss the parallel transport along principal null directions in these spacetimes. Such directions coincide with the eigenvectors of the principal conformal Killing-Yano tensor. Finally, we show how to obtain a parallel-transported frame along null geodesics in the background of the 4D Plebanski-Demianski metric which admits only a conformal generalization of the Killing-Yano tensor.Comment: 17 pages, no figure

    The effect of an intervention to improve newly qualified teachers’ interpersonal style, students motivation and psychological need satisfaction in sport-based physical education

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    Recent developments in self-determination theory research in the educational setting (e.g., Reeve, Deci, & Ryan, 2004), suggest that teachers’ interpersonal style should be considered as consisting of three dimensions: autonomy-support, structure and interpersonal involvement. Based on this theoretical proposition, the purpose of the present study was to test the effects of a training program for three physical education newly qualified teachers on the aforementioned teachers’ overt behaviors and students’ psychological needs satisfaction, self-determined motivation and engagement in sport-based physical education. After a baseline period of four lessons, the teachers attended an informational session on adaptive student motivation and how to support it. The training program also included individualized guidance during the last four lessons of the cycle. Results revealed that from pre- to post-intervention: (1) teachers managed to improve their teaching style in terms of all three dimensions, and (2) students were receptive to these changes, as shown by increases in their reported need satisfaction, self-determined motivation and engagement in the class

    Regurgitation Hemodynamics Alone Cause Mitral Valve Remodeling Characteristic of Clinical Disease States In Vitro

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    Mitral valve regurgitation is a challenging clinical condition that is frequent, highly varied, and poorly understood. While the causes of mitral regurgitation are multifactorial, how the hemodynamics of regurgitation impact valve tissue remodeling is an understudied phenomenon. We employed a pseudo-physiological flow loop capable of long-term organ culture to investigate the early progression of remodeling in living mitral valves placed in conditions resembling mitral valve prolapse (MVP) and functional mitral regurgitation (FMR). Valve geometry was altered to mimic the hemodynamics of controls (no changes from native geometry), MVP (5ᅠmm displacement of papillary muscles towards the annulus), and FMR (5ᅠmm apical, 5ᅠmm lateral papillary muscle displacement, 65% larger annular area). Flow measurements ensured moderate regurgitant fraction for regurgitation groups. After 1-week culture, valve tissues underwent mechanical and compositional analysis. MVP conditioned tissues were less stiff, weaker, and had elevated collagen III and glycosaminoglycans. FMR conditioned tissues were stiffer, more brittle, less extensible, and had more collagen synthesis, remodeling, and crosslinking related enzymes and proteoglycans, including decorin, matrix metalloproteinase-1, and lysyl oxidase. These models replicate clinical findings of MVP (myxomatous remodeling) and FMR (fibrotic remodeling), indicating that valve cells remodel extracellular matrix in response to altered mechanical homeostasis resulting from disease hemodynamics

    Scalable magnet geometries enhance tumour targeting of magnetic nano-carriers

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    Targeted drug delivery systems aim to increase therapeutic effect within the target tissue or organ, while reducing off-target toxicity associated with systemic delivery. Magnetic drug targeting has been shown to be an effective strategy by manipulating therapeutics inside the body using a magnetic field and an iron oxide carrier. However, the effective targeting range of current magnets limits this method to small animal experiments or superficial parts of the human body. Here we produce clinically translatable magnet designs capable of increasing exposure of tissue to magnetic fields and field gradients, leading to increased carrier accumulation. The iron oxide nanoparticle capturing efficiency was first assessed in vitro using a simple vascular flow system. Secondly, accumulation of these particles, following magnetic targeting, was evaluated in vivo using a range of different magnet designs. We observed that our bespoke magnet produced a 4-fold increase in effective targeting depth when compared to a conventional 1 T disk magnet. Finally, we show that this magnet is readily scalable to human size proportions and has the potential to target 100 nm particles up to a depth of 7 cm at specific locations of human body

    Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours

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    Stem cells have been utilised as anti-cancer agents due to their ability to home to and integrate within tumours. Methods to augment stem cell homing to tumours are being investigated with the goal of enhancing treatment efficacy. However, it is currently not possible to evaluate both cell localisation and cell viability after engraftment, hindering optimisation of therapy. In this study, luciferase-expressing human adipocyte-derived stem cells (ADSCs) were incubated with Indium-111 radiolabelled iron oxide nanoparticles to produce cells with tri-modal imaging capabilities. ADSCs were administered intravenously (IV) or intracardially (IC) to mice bearing orthotopic breast tumours. Cell fate was monitored using bioluminescence imaging (BLI) as a measure of cell viability, magnetic resonance imaging (MRI) for cell localisation and single photon emission computer tomography (SPECT) for cell quantification. Serial monitoring with multi-modal imaging showed the presence of viable ADSCs within tumours as early as 1-hour post IC injection and the percentage of ADSCs within tumours to be 2-fold higher after IC than IV. Finally, histological analysis was used to validate engraftment of ADSC within tumour tissue. These findings demonstrate that multi-modal imaging can be used to evaluate the efficiency of stem cell delivery to tumours and that IC cell administration is more effective for tumour targeting

    Factors influencing implementation of aerobic exercise after stroke: a systematic review

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    Objectives: This systematic review aimed to explore the perspectives of healthcare, exercise, and fitness professionals working with people post-stroke regarding the factors affecting the implementation of aerobic exercise after stroke. Data Sources: OVID SP MEDLINE, OVID SP EMBASE, and CINAHL were searched from inception to December 2018 using a combination of search terms with synonyms of stroke, aerobic exercise and barriers/facilitators. Review methods: Studies focusing on the factors affecting implementation of aerobic exercise after stroke from staff perspectives were included with no restriction on the types of study design. For inclusivity, a broad definition of aerobic exercise was used. Review authors independently extracted data from included studies using domains from the Consolidated Framework for Implementation Research, then synthesised using a framework synthesis approach. Retrospective automated screening was conducted using Rayyan software. Results: Twenty studies were included. Four reported on implementation of aerobic exercise, sixteen on general exercise interventions, all post-stroke. Factors identified as influencing implementation of aerobic exercise after stroke included professionals’ self-efficacy and knowledge about stroke, patients’ needs, communication and collaboration within and between organisations and resources such as equipment, staff and training. Conclusions: Key factors influencing the implementation of aerobic exercise after stroke included characteristics of the staff and intervention and system-level issues, some of which are modifiable. Further research should evaluate strategies which specifically target these modifiable factors to facilitate implementation in practice
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