2,625 research outputs found

    The Apologies of Australia, Canada and the United States to Historically Subjugated Peoples: On argumentation, reconciliation, and forgiveness

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    In 2008, the governments of Australia and Canada apologized to indigenous peoples of each respective country for past wrongs, while the United States House of Representatives offered an apology to African peoples and their descendants for slavery. This paper conducts a comparative analysis of the three national moments to explore the capacities for language-based argumentation to invite forgiveness, mitigate historical social injustices, and promote inter-cultural accord that weaves temporal sinews of reconciliation

    Graduate Counseling Students\u27 Learning, Development, and Retention of Knowledge

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    The present study investigated 52 graduate counseling students’ levels of ethical and legal knowledge (Lambie, Hagedorn, & Ieva, 2010) and social cognitive development (Hy & Loevinger, 1996) at three points: (a) prior to a counseling ethics course, (b) at the completion of the course, and (c) four months later. Students’ ethical and legal knowledge scores increased and they retained their learning; however, their social-cognitive development did not change. Implications for the scholarship of teaching and learning are discussed

    ABE: providing a low-delay service within best effort

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    Alternative best effort (ABE) is a novel service for IP networks, which relies on the idea of providing low delay at the expense of possibly less throughput. The objective is to retain the simplicity of the original Internet single-class best-effort service while providing low delay to interactive adaptive applications

    Clinical Electroencephalography for Anesthesiologists

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    The widely used electroencephalogram-based indices for depth-of-Anesthesia monitoring assume that the same index value defines the same level of unconsciousness for all anesthetics. In contrast, we show that different anesthetics act at different molecular targets and neural circuits to produce distinct brain states that are readily visible in the electroencephalogram. We present a two-part review to educate anesthesiologists on use of the unprocessed electroencephalogram and its spectrogram to track the brain states of patients receiving anesthesia care. Here in part I, we review the biophysics of the electroencephalogram and the neurophysiology of the electroencephalogram signatures of three intravenous anesthetics: propofol, dexmedetomidine, and ketamine, and four inhaled anesthetics: sevoflurane, isoflurane, desflurane, and nitrous oxide. Later in part II, we discuss patient management using these electroencephalogram signatures. Use of these electroencephalogram signatures suggests a neurophysiologically based paradigm for brain state monitoring of patients receiving anesthesia care.National Institutes of Health (U.S.) (Grant DP1-OD003646)National Institutes of Health (U.S.) (Grant TR01-GM104948

    Implementing Pharmacy Informatics in College Curricula: The AACP Technology in Pharmacy Education and Learning Special Interest Group

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    Many professional organizations have initiatives to increase the awareness and use of informatics in the practice of pharmacy. Within education we must respond to these initiatives and make technology integral to all aspects of the curriculum, inculcating in students the importance of technology in practice. This document proposes 5 central domains for organizing planning related to informatics and technology within pharmacy education. The document is intended to encourage discussion of informatics within pharmacy education and the implications of informatics in future pharmacy practice, and to guide colleges of pharmacy in identifying and analyzing informatics topics to be taught and methods of instruction to be used within the doctor of pharmacy curriculum

    The Stratigraphic Nomenclature of the Irish Offshore Basins

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    Over 50 years of research and exploration in the Irish offshore have provided a vast archive of geological and geophysical information from which the geological evolution of the region has been pieced together. A total of 161 exploration and appraisal wells, a significant number of development wells and a small number of important shallower boreholes have been drilled, while a very large volume of 2D and 3D seismic data has been acquired across the Irish offshore. In addition, a number of important regional wide-angle seismic reflection and refraction profiles have helped constrain the deep crustal structure and controls on the main basins. The history of exploration has been summarised in various publications, including Naylor & Shannon (2011) and Shannon (2018)

    CELLvo Matrix Manufacturing Improvement

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    StemBioSys seeks to streamline their CELLvo matrix manufacturing process in order to decrease the cost of production. The main objectives of this project are to design, build, and test a system that StemBioSys can utilize to complete the decellularization process more quickly, with greater efficiency, and with lower production costs. The following report covers the features of our complete design and its three subsystems that combine to accomplish the individual tasks of the decellularization process. The primary functions of the three subsystems are as follows: the flask organizer holds 6 flasks together throughout the process, the guide positions the flask organizer at the desired angle for aspiration steps, and the liquid network dispenses reagents into the flasks for the washing steps. Following the design overview is an evaluation of the final design through the scope of project requirements and constraints, as well as the associated tests used in assessing the overall system\u27s performance. The design constraints of sterility, maintaining the integrity of the CELLvo Matrix, remaining within the provided budget, and the available space for the final process were all satisfied through our design solution. The sterility constraint is satisfied with the use of one of the recommended materials in Section 2.6. The integrity of the CELLvo Matrix was confirmed by checking that the matrix was not scratched or damaged during the aspiration or dispensing steps. Our final design was able to complete multiple runs of the decellularization process in a biosafety cabinet (BSC) without any damage to the subsystems or flasks, thus meeting the design constraint for the available space. Our budget was to remain under 1,200,andtheAvENGRsspentroughlyatotalof1,200, and the AvENGRs spent roughly a total of 223 to satisfy this constraint. Our final design is held to many project requirements that will be detailed in the following sections. The requirement that our solution is to be optimized for Tl50 cell culture flasks is met through the three subsystems\u27 abilities to specifically fit T150 flasks. The liquid network subsystem is able to satisfy the requirement of effectively washing away all detergent without damaging the matrices, which contributes to the production of a uniform project. Additionally, the liquid network has multiple frames and bases that allow for the device to be versatile and portable. Moreover, the flask organizer and guide subsystems are designed so they can easily be reproduced and sterilized, and the quantity produced can be scaled to accommodate the various sizes of manufacturing runs. Since our final solution did not alter the foundation of the decellularization process, we maintain the assumption that our subsystems are capable of producing a uniform product, can be integrated into the current process, can be easily adopted by staff and are compatible with OSHA codes and prevailing industry standards. In addition, the process must be performed in a biosafety cabinet and should be able to accommodate any other processes conducted simultaneously, which were both satisfied during prototype testing. Lastly, the implementation of our three subsystems decreases the total time required to complete the decellularization process, satisfying this requirement. Our overall project requirement to reduce Full-Time Equivalents (FTEs) was also satisfied, as a reduction in time decreases the necessary time for one person to work. Overall, the AvENGRs have created a successful, working prototype to streamline the· CELLvo matrix manufacturing process. Since all of our requirements and constraints were met, there are no changes needed to achieve remaining goals, but there is always room for the improvement of our working prototype. As a result of the COVID-19 pandemic, the project remains unfinished in terms of producing several polished copies of each subsystem. Therefore, the AvENGRs have provided manufacturing recommendations should StemBioSys choose to further the development of our solution (Section 2.6 and Appendix 5.4)
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