Assesment of Water Quality Parameters of Ulhas River in Thane District

Globally water resources are becoming increasingly vulnerable as a result escalating demand arising from the population growth, the need foe increased food production, expanding industrialisation due to rising living standards, pilution due to various anthropogenic activities, and climate change impacts Due to the water scarcity and poor water quality, it has been predicted that by 2050, at least one in four people are likely to live in a country with a shortage of freshwater. Water quality is a complex subject which involves physical, chemical, hydrological and biologicl characteristics of water and their complex and delicate realations

An Overview On Web Scraping Techniques And Tools

From the evolution of WWW, the scenario of internet user and data exchange is fastly changes. As common people join the internet and start to use it, lots of new techniques are promoted to boost up the network. At the same time, to enhance computers and network facility new technologies were introduces which results into automatically decreasing in cost of hardware and website�s related costs. Due to all these changes, large number of users are joined and use the internet facilities. Daily use of internet cose in to a tremendous data is available on internet. Business, academician, researchers all are share their advertisements, information on internet so that they can be connected to people fastly and easily. As a result of exchange, share and store data on internet, a new problem is arise that how to handle such data overload and how the user will get or access the best information in least efforts. To solve this issues, researcher spotout new technique called Web Scraping. Web scraping is very imperative technique which is used to generate structured data on the basis of available unstructured data on the web. Scaping generated structured data then stored in central database and analyze in spreadsheets. Traditional copy-and-paste, Text grapping and regular expression matching, HTTP programming, HTML parsing, DOM parsing, Webscraping software, Vertical aggregation platforms, Semantic annotation recognizing and Computer vision web-page analyzers are some of the common techniques used for data scraping. Previously most user uses the common copy-pest technique for gathering and analyzing data on the internet, but it is a tedious technique where lot of data copied by the user and store on computer files. As compared to this technique web scraping software is easiest scraping technique. Now a days, there are lots of software are available in the market for web scraping. Our paper is focused on the overview on the information extraction technique i.e. web scraping, different techniques of web scraping and some of the recent tools used for a web scraping

Removal of a below knee plaster cast worn for 28 months: a case report

<p>Abstract</p> <p>Introduction</p> <p>An unusual situation in which a below knee cast was removed after 28 months is reported. To the best of our knowledge no similar cases have been reported in the literature.</p> <p>Case presentation</p> <p>The cast was removed from the leg of a 45-year-old Caucasian woman. Significant muscle atrophy and dense skin scales were present but the underlying skin surface was relatively healthy with only small pitted 1-2 mm ulcers. No pathogenic organisms were cultured from this environment.</p> <p>Conclusion</p> <p>It seems likely that skin can tolerate cast immobilization for prolonged duration.</p

The WHO QualityRights initiative: Building partnerships among psychiatrists, people with lived experience and other key stakeholders to improve the quality of mental healthcare

Psychiatrists have an essential role to play in promoting human rights in mental healthcare. The World Health Organization's QualityRights initiative, in partnership with different stakeholders, is improving the quality of psychiatric care in different countries

A review of issues and challenges

Determining the ages of young planetary surfaces relies on using populations of small, often sub-km diameter impact craters due to the higher frequency at which they form. Smaller craters however can be less reliable for estimating ages as their size-frequency distribution is more susceptible to alteration with debate as to whether they should be used at all. With the current plethora of meter-scale resolution images acquired of the lunar and Martian surfaces, small craters have been widely used to derive model ages to establish the temporal relation of recent geologic events. In this review paper, we discuss the many factors that make smaller craters particularly challenging to use and should be taken into consideration when crater counts are confined to small crater diameters. Establishing confidence in a model age ultimately requires an understanding of the geologic context of the surface being dated as reliability can vary considerably and limitations of the dating technique should be considered in applying ages to any geologic interpretation

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

The ATP-dependent degradation of polyubiquitylated proteins by the 26S proteasome is essential for the maintenance of proteome stability and the regulation of a plethora of cellular processes. Degradation of substrates is preceded by the removal of polyubiquitin moieties through the isopeptidase activity of the subunit Rpn11. Here we describe three crystal structures of the heterodimer of the Mpr1-Pad1-N-terminal domains of Rpn8 and Rpn11, crystallized as a fusion protein in complex with a nanobody. This fusion protein exhibits modest deubiquitylation activity toward a model substrate. Full activation requires incorporation of Rpn11 into the 26S proteasome and is dependent on ATP hydrolysis, suggesting that substrate processing and polyubiquitin removal are coupled. Based on our structures, we propose that premature activation is prevented by the combined effects of low intrinsic ubiquitin affinity, an insertion segment acting as a physical barrier across the substrate access channel, and a conformationally unstable catalytic loop in Rpn11. The docking of the structure into the proteasome EM density revealed contacts of Rpn11 with ATPase subunits, which likely stabilize the active conformation and boost the affinity for the proximal ubiquitin moiety. The narrow space around the Rpn11 active site at the entrance to the ATPase ring pore is likely to prevent erroneous deubiquitylation of folded proteins