Annex instrumental per a la redacció dels Plans Directors i les Àrees Residencials Estratègiques

2012/201

Plec de recomanacions per a la redacció dels Plans Directors i les Àrees Residencials Estratègiques

2012/201

El Plan director urbanístico “Vies Blaves Barcelona” (PDU VBB): los nuevos caminos para la regeneración del Territorio, el ocio y salud de la ciudadanía

El Plan director urbanístico (PDU) “Vies Blaves Barcelona” (Vías Azules Barcelona en castellano) ha sido probado definitivamente el año 2020). Lo impulsan y gestionan la Diputación de Barcelona con la Generalitat de Catalunya, sinérgica y concertadamente con Ayuntamientos del territorio, y que integra en términos de participación a distintas Asociaciones e Instituciones civiles desde el 2016. El desarrollo del plan recuperará la articulación el territorio con los ámbitos de ribera de los cauces de los ríos Llobregat, Anoia y Cardener. La propuesta en proceso, plantea adecuar 306 kilómetros de caminos para peatones y medios no motorizados, como la bicicleta o el caballo. “Vies Blaves” pasarán por 59 municipios, abarcando un total de 7 comarcas (Alt Penedès, Anoia, Bages, Baix Llobregat, Berguedà, Moianès y Barcelona), 59 municipios y conectando cerca de 5 millones de personas con un patrimonio natural, cultural, gastronómico y arquitectónico único en la provincia.Peer ReviewedPostprint (author's final draft

El Prat de Llobregat. Eixample sud

Postprint (published version

Pla Director Urbanístic de les àrees residencials estratègiques de l'àmbit del Vallès Occidental

Postprint (published version

El Prat de Llobregat. Ronda Sud-Aeroport

Postprint (published version

Programmed death-ligand (PD-L1), epidermal growth factor (EGF), relaxin and metalloproteinase-3 (MMP3), potential biomarkers of malignancy in canine mammary neoplasia

Gene expression has been suggested as a putative tool for prognosis and diagnosis in canine mammary neoplasia (CMNs). In the present study, 58 formalin-fixed paraffin-embedded (FFPE) paraffined canine mammary neoplasias from 27 different bitches were included. Thirty-seven tumours were classified as benign, whereas thirty-one were classified as different types of canine carcinoma. In addition, mammary samples from three healthy bitches were also included. The gene expression for vascular endothelial growth factor-α (VEGFα), CD20, progesterone receptor (PGR), hyaluronidase-1 (HYAL-1), programmed death-ligand 1 (PD-L1), epidermal growth factor (EGF), relaxin (RLN2), and matrix metalloproteinase-3 (MMP3) was assessed through RT-qPCR. All the assessed genes yielded a higher expression in neoplastic mammary tissue than in healthy tissue. All the evaluated genes were overexpressed in neoplastic mammary tissue, suggesting a role in the process of tumorigenesis. Moreover, PD-L1, EGF, relaxin, and MMP3 were significantly overexpressed in malignant CMNs compared to benign CMNs, suggesting they may be useful as malignancy biomarkers

Canine Mammary Neoplasia Induces Variations in the Peripheral Blood Levels of CD20, CD45RA, and CD99

The idea of using tumour biomarkers as diagnostic tools is progressively increasing. Of these, serum biomarkers are of particular interest, as they can provide rapid results. In the present study, serum samples from 26 bitches diagnosed with mammary tumours, plus 4 healthy bitches, were obtained. The samples were analysed using CD antibody microarrays targeting 90 CD surface markers and 56 cytokines/chemokines. A total of five CD proteins, namely CD20, CD45RA, CD53, CD59, and CD99, were selected and further analysed, utilizing immunoblotting techniques to validate the microarray results. CD45RA showed a significantly lower abundance in the serum samples from the bitches carrying mammary neoplasia in comparison to the healthy animals. Regarding CD99, the serum samples from the neoplastic bitches showed it in a significantly higher abundance than those from the healthy patients. Finally, CD20 showed a significantly higher abundance in bitches carrying a malignant mammary tumour in comparison to healthy patients, but no differential expression between malignant and benign tumours was observed. According to these results, both CD99 and CD45RA are indicators of mammary tumour presence, but without distinguishing between malignant and benign

Melatonin receptors MT1 and MT2 are expressed in spermatozoa from several seasonal and nonseasonal breeder species

P. 1958-1968Melatonin is a ubiquitous and multipurpose molecule, and one of its roles is to regulate reproduction in some seasonal mammals. Our group has previously reported the variation in the melatonin levels in ram seminal plasma along the year and identified MT1 and MT2 receptors in ram spermatozoa. The objective of this study was to elucidate whether the presence of melatonin receptors (MT1 and MT2) in the sperm plasma membrane, and melatonin in the seminal plasma is related to seasonal breeding. For this purpose, the presence of melatonin receptors and the levels of melatonin in seminal plasma have been examined in several species: donkey and stallion as long-day breeders; red deer as a wild, short-day, highly seasonal breeder (epididymal spermatozoa); bull as a conventional nonseasonal breeder; boar as a seasonal breeder under management techniques; and dog as possible a seasonal breeder not regulated by melatonin. We have detected measurable levels of melatonin in the seminal plasma of all ejaculated semen samples (from donkey, stallion, boar, bull, and dog). Also, and for the first time, we have demonstrated the presence of MT1 and MT2 melatonin receptors in the spermatozoa of all these species, regardless their type of reproduction or sperm source (ejaculated or epididymal), using indirect immunofluorescence techniques and Western blotting. Our findings suggest that melatonin and melatonin receptors may be universally distributed in the reproductive system of mammals and that the sperm melatonin receptors cells may not be necessarily related with seasonal reproduction. Furthermore, the presence of MT1 at the cytoplasmic droplet in immature ejaculated stallion spermatozoa found in one sample and epididymal red deer spermatozoa suggests that melatonin may be involved in specific functions during spermatogenesis and sperm maturation, like protecting spermatozoa from oxidative damage, this activity being mediated through these receptors.S

Agile Business Intelligence Governance: Su justificación y presentación

Actas del III Congreso Interacadémico itSMF España / Universidad Carlos III de Madrid celebrado el 13 de mayo de 2008 en la Universidad Carlos III de Madrid (Leganés, Madrid