Biological control of Prays Oleae (BERN.) By chrysopids in tras-os-Montes region (Northeastern Portugal)

A study was carried out in an olive grove in the Tras-os-Montes region, in the period 1993 to 1996 to establish the rate of predation of chrysopids on Prays oleae (Bern.) eggs. Data on a trial conducted in 1996 to evaluate the effectiveness of field releases of Chrysoperla carnea (Steph.) in controlling eggs of the carpophagous generation of the pest are also reported. Six species of Chrysopidae have been collected. The most abundant were C. carnea and Mallada flavifrons (Brauer) which together represented about 74% of total captures. The main period of adult catches occurred between July and October. The rate of predation by chrysopids on P. oleae eggs varied among different generations of the pest and in different years, reaching 34% for the carpophagous generation in 1996. The potential damage that might be expected from the studied population of P. oleae was almost halved by releasing 360 larvae of C. carnea per tree.PAMAF lED no 611

Hospital Resource Utilization and Treatment Cost of Skeletal-Related Events in Patients with Metastatic Breast or Prostate Cancer: Estimation for the Portuguese National Health System

BACKGROUND: Skeletal-related events (SREs) occur frequently in patients with bone metastases as a result of breast (BC) and prostate (PC) cancers. They increase both morbidity and mortality and lead to extensive health-care resource utilization. METHODS: Health care resource utilization by BC/PC patients with at least one SRE during the preceding 12 months was assessed through retrospective chart review. SRE-treatment costs were estimated using the Portuguese Ministry of Health cost database and analyzed using generalized linear models. RESULTS: This study included 152 patients from nine hospitals. The mean (SD) annual SRE-treatment cost per patient was €5963 (€3646) and €5711 (€4347), for BC (n=121) and PC (n=31) patients, respectively. Mean cost per single episode ranged between €1485 (radiotherapy) and €13,203 (spinal cord compression). Early onset of bone metastasis (P = 0.03) and diagnosis of bone metastases at or after the occurrence of the first SRE (P < 0.001) were associated with higher SRE-treatment costs. CONCLUSION: These results reveal the high hospital SRE-treatment costs, highlighting the need for early diagnosis and treatment, and identify key factors determining the economic value of therapies for patients with skeletal metastases

Carcinogênese Hepática no Norte do Paraná e Uso Indiscriminado de Defensivos Agrícolas

Introdução a um programa de pesquisa visando esclarecer uma possível influência dos inseticidas organoclorados na etiologia dos tumores hepáticos primários na população do norte do Estado do Paraná, Brasil

A cultura do limão-taiti.

Clima; Solo; Clones; Plantio; Adubação; Irrigação; Controle de invasoras; Culturas intercalares; Pragas e seu controle; Doenças e seu controle; Colheita; Coeficiente de produção.bitstream/item/162294/1/A-cultura-do-limao-taiti.pdf2. ed. rev. aument

Cultivo dos citros.

O trabalho faz referências ao clima e solos mais apropriados para os citros; bem como a um conjunto de praticas recomendadas para a exploração comercial da cultura, contemplando a indicação de variedades copa, porta-enxertos, o controle de pragas e doenças, culturas intercalares, colheita e comercialização.bitstream/item/88908/1/Cultivo-dos-Citros-Almir-sobrinho-Circular-tecnica-26-1996.pdfMemória

The effects of adding zoledronic acid to neoadjuvant chemotherapy on tumour response: exploratory evidence for direct anti-tumour activity in breast cancer

Background: Pre-clinical studies have demonstrated synergistic anti-tumour effects of chemotherapy (CT) and zoledronic acid (ZOL). Within the AZURE trial, designed to determine whether the addition of ZOL to neoadjuvant therapy improves disease outcomes, a subgroup received neoadjuvant CT. We report a retrospective evaluation comparing pathological response in the primary tumour between treatment groups. Methods: In total, 205 patients received neoadjuvant CT±ZOL (CT+ZOL, n=102; CT, n=103). The primary end point was pathologically assessed residual invasive tumour size (RITS) at surgery. Secondary end points were pathological complete response (pCR) rate and axillary nodal involvement. Following review of surgical pathology reports (n=195), outcome differences between groups were assessed adjusting for potential response modifiers. Results: Baseline characteristics and CT treatments were similar. In multivariate analysis, allowing for biological and clinical factors known to influence tumour response, the adjusted mean RITS in CT and CT+ZOL groups were 27.4 and 15.5 mm, respectively, giving a difference in means of 12 mm (95% confidence interval: 3.5–20.4 mm; P=0.006). The pCR rate was 6.9% in the CT group and 11.7% in the CT+ZOL group (P=0.146). There was no difference in axillary nodal involvement (P=0.6315). Conclusion: These data suggest a possible direct anti-tumour effect of ZOL in combination with CT, warranting formal evaluation in prospective studies