Market surveys: Barotse floodplain system

The aim of the CGIAR Research Program on Aquatic Agricultural Systems (AAS) is to improve livelihoods and food security by enhancing the productivity and diversity of aquatic and agricultural systems. The AAS program in the Barotse floodplain of Zambia, which is being implemented in ten communities including; Kabula, Kapanda Lealui, Mapungu, Mwandi, Nalitoya, Nembwele, Senanga, Sifuna and Situlu in December 2014, in Nanikelako in April 2015 and in Mwandi, evaluates changes in seasonal flooding patterns and the availability of natural resources to strengthen the productivity of aquatic agricultural management practices and improve the livelihoods of the poor and vulnerable. It is essential to understand the current food and nutrition security situation in the Barotse floodplain in order to support the AAS program objective. Food availability in the Barotse is highly seasonal; it becomes limited from August or September to January, during which time food and nutrition insecurity worsens. It is therefore necessary to identify opportunities to promote sustainable and diverse dietary options. This narrative provides an explanation of how the market research was conducted and some preliminary results. Overall, our research indicates that poor market access is a significant constraint in the Barotse floodplain, inhibiting AAS community members from securing proper nutrition and food

Food and nutrition security in the Barotse floodplain system

The CGIAR Research Program on Aquatic Agricultural Systems (AAS) is being implemented in ten communities in the Barotse floodplain of Zambia’s Western Province. With a focus on the rural poor and vulnerable, the AAS program aims to reduce poverty and improve food security by harnessing the development potential, productivity and diversity of aquatic and agricultural systems. The development challenge in the Barotse floodplain, as identified by relevant stakeholders, is to make effective use of seasonal flooding patterns and natural resources through more productive and diversified aquatic agricultural management practices that improve the lives and livelihoods of the poor and vulnerable. Food and nutrition are essential to support the overall AAS program objective and overcome the specific development challenge of the Barotse floodplain. Zambia has very high malnutrition rates, particularly for stunting in children under five. Poor nutritional status, especially of women and children, inhibits individual growth and development, and negatively impacts the overall health, productivity and economic potential of a community. The purpose of this report is to analyze the food and nutrition security situation within the Barotse floodplain. It explores multiple sectors, including nutrition, agriculture, health, and gender, at the national, provincial and community level to provide a comprehensive understanding of food and nutrition in the ten AAS communities in relation to the country as a whole. The analysis will provide informative inputs to the AAS Barotse hub design process to develop an appropriate food and nutrition research-in-development agenda

Effects of ventilator settings, nebulizer and exhalation port position on albuterol delivery during non-invasive ventilation: an in-vitro study.

BACKGROUND:Few studies have investigated the factors affecting aerosol delivery during non-invasive ventilation (NIV). Our aim was to investigate, using a bench-top model, the effect of different ventilator settings and positions of the exhalation port and nebulizer on the amount of albuterol delivered to a lung simulator. METHODS: A lung model simulating spontaneous breathing was connected to a single-limb NIV ventilator, set in bi-level positive airway pressure (BIPAP) with inspiratory/expiratory pressures of 10/5, 15/10, 15/5, and 20/10 cmH2O, or continuous positive airway pressure (CPAP) of 5 and 10 cmH2O. Three delivery circuits were tested: a vented mask with the nebulizer directly connected to the mask, and an unvented mask with a leak port placed before and after the nebulizer. Albuterol was collected on a filter placed after the mask and then the delivered amount was measured with infrared spectrophotometry. RESULTS: Albuterol delivery during NIV varied between 6.7\u2009\ub1\u20090.4% to 37.0\u2009\ub1\u20094.3% of the nominal dose. The amount delivered in CPAP and BIPAP modes was similar (22.1\u2009\ub1\u200910.1 vs. 24.0\u2009\ub1\u200910.0%, p\u2009=\u20090.070). CPAP level did not affect delivery (p\u2009=\u20090.056); in BIPAP with 15/5 cmH2O pressure the delivery was higher compared to 10/5 cmH2O (p\u2009=\u20090.033) and 20/10 cmH2O (p\u2009=\u20090.014). Leak port position had a major effect on delivery in both CPAP and BIPAP, the best performances were obtained with the unvented mask, and the nebulizer placed between the leak port and the mask (p\u2009<\u20090.001). CONCLUSIONS: In this model, albuterol delivery was marginally affected by ventilatory settings in NIV, while position of the leak port had a major effect. Nebulizers should be placed between an unvented mask and the leak port in order to maximize aerosol delivery

Ultimate strength

Concern for the ductile behaviour of ships and offshore structures and their structural components under ultimate conditions. Attention shall be given to the influence of fabrication imperfections and in-service damage and degradation on reserve strength

Early impact of abdominal compartment syndrome on liver, kidney and lung damage in a rodent model

Background: Abdominal compartment syndrome (ACS) sometimes occurs in critically ill patients following damage control surgery. The purpose of the present study was to develop a model of ACS and to evaluate its pathologic impact on liver, kidney, and lung morphology. Methods: Twenty Wistar rats (mass 300\u2013350 g) were randomly divided into four groups: 1) intra-abdominal hypertension (IAH): a laparotomy was performed and the abdomen packed with cotton until an intra-abdominal pressure (IAP) of 15 mm Hg was reached; 2) hypovolemia (HYPO): blood was withdrawn until a mean arterial pressure ~60 mm Hg was reached; 3) IAH + HYPO (to resemble clinical ACS); and 4) sham surgery. After 3 hours of protective mechanical ventilation, the animals were euthanized and the liver, kidney and lungs removed to examine the degree of tissue damage. Results: IAH resulted in the following: oedema and neutrophil infiltration in the kidney; necrosis, congestion, and microsteatosis in the liver; and alveolar collapse, haemorrhage, interstitial oedema, and neutrophil infiltration in the lungs. Furthermore, IAH was associated with greater cell apoptosis in the kidney, liver and lungs compared to sham surgery. HYPO led to oedema and neutrophil infiltration in the kidney. The combination of IAH and HYPO resulted in all the aforementioned changes in lung, kidney and liver tissue, as well as exacerbation of the inflammatory process in the kidney and liver and kidney cell necrosis and apoptosis. Conclusions: Intra-abdominal hypertension by itself is associated with kidney, liver and lung damage; when combined with hypovolemia, it leads to further impairment and organ damage

Geophysical monitoring of Stromboli volcano: insight into recent volcanic activity

Stromboli is an open conduit strato-volcano of the Aeolian archipelago (Italy), characterized by typical Strom-bolian explosive activity, lasting for several centuries, and by the emission of huge amounts of gas. The normalactivity of Stromboli is characterized by some hundreds of moderate explosions per day. Major explosions, whichlaunch scoria up to hundreds of meters from the craters, lava flows and paroxysmal explosions, which producelarge ballistic blocks, sometimes take place. During the effusive eruption in 2002 - 2003, which caused a tsunamiwith waves of about 10 meters high along the coasts of the Island, the monitoring system was enhanced. In 2006INGV has added two Sacks-Evertson borehole volumetric dilatometers to the surveillance system, in order to mon-itor changes in the local strain field by measuring areal strain. Today we have a large amount of geophysical dataand observations that allow us to better understand how this volcano works. After a period of low explosive activitystarted in mid-2014, Stromboli has shown a more intense explosive activity in the last few months. During the re-cent phase of increased activity, the geophysical monitoring system detected four major explosions occurred on 26July, 23 October, 1 November and 1 December 2017, respectively. The current phase of reawakening of Strombolivolcano has led the Italian civil protection authorities to decree the "attention" alert level (yellow) on the Island.PublishedVienna, Austria1IT. Reti di monitoraggio e sorveglianz

Thermal characterization of direct wafer bonded Si-on-SiC

Direct bonded Si-on-SiC is an interesting alternative to silicon-on-insulator (SOI) for improved thermal management in power conversion and radio frequency applications in space. We have used transient thermoreflectance and finite element simulations to characterize the thermal properties of direct bonded Si-on-4H–SiC samples, utilizing a hydrophobic and hydrophilic bonding process. In both instances, the interface has good thermal properties resulting in TBReff values of 6 + 4/−2 m2 K GW−1 (hydrophobic) and 9 + 3/−2 m2 K GW−1 (hydrophilic). Two-dimensional finite element simulations for an equivalent MOSFET showed the significant thermal benefit of using Si-on-SiC over SOI. In these simulations, a MOSFET with a 200 nm thick, 42 μm wide Si drift region was recreated on a SOI structure (2 μm buried oxide) and on the Si-on-SiC material characterized here. At 5 W mm−1 power dissipation, the Si-on-SiC was shown to result in a >60% decrease in temperature rise compared to the SOI structure

Guideline on carotid surgery for stroke prevention: updates from the Italian Society of Vascular and Endovascular Surgery. A trend towards personalized medicine

Background: This guideline (GL) on carotid surgery as updating of "Stroke: Italian guidelines for Prevention and Treatment" of the ISO-SPREAD Italian Stroke Organization-Group, has recently been published in the National Guideline System and shared with the Italian Society of Vascular and Endovascular Surgery (SICVE) and other Scientific Societies and Patient's Association. Methods: GRADE-SIGN version, AGREE quality of reporting checklist. Clinical questions formulated according to the PICO model. Recommendations developed based on clinical questions by a multidisciplinary experts' panel and patients' representatives. Systematic reviews performed for each PICO question. Considered judgements filled by assessing the evidence level, direction, and strength of the recommendations. Results: The panel provided indications and recommendations for appropriate, comprehensive, and individualized management of patients with carotid stenosis. Diagnostic and therapeutic processes of the best medical therapy, carotid endarterectomy (CEA), carotid stenting (CAS) according to the evidences and the judged opinions were included. Symptomatic carotid stenosis in elective and emergency, asymptomatic carotid stenosis, association with ischemic heart disease, preoperative diagnostics, types of anesthesia, monitoring in case of CEA, CEA techniques, comparison between CEA and CAS, post-surgical carotid restenosis, and medical therapy are the main topics, even with analysis of uncertainty areas for risk-benefit assessments in the individual patient (personalized medicine [PM]). Conclusions: This GL updates on the main recommendations for the most appropriate diagnostic and medical-surgical management of patients with atherosclerotic carotid artery stenosis to prevent ischemic stroke. This GL also provides useful elements for the application of PM in good clinical practice