Quelle est l'activité du médecin généraliste au cours de la grossesse et du post-partum? ((à partir de l'étude ECOGEN))

La thèse se base sur l'analyse des résultats de l'étude ECOGEN, étude transversale multicentrique nationale, réalisée de novembre 2011 à avril 2012, en patientèle de médecine générale. L'interne, observateur pendant une journée par semaine chez ses maîtres de stage, notait les éléments de la consultation. Les motifs, procédures et résultats de consultation étaient codés selon la Classification Internationale des Soins Primaires. Les données analysées concernent les résultats de consultation intéressant une grossesse en cours ou un post-partum. L'étude ECOGEN a recueilli 20781 consultations, sur 128 lieux. 1,2% des consultations concernaient la prise en charge d'une grossesse ou d'un post-partum. 66,10% de ces consultations aboutissaient à la prise en charge d'une grossesse normale. 76,10% des motifs de consultation concernaient directement la grossesse ou le post-partum, tandis que 23,9% concernaient d'autres motifs. Le médecin généraliste prenait en charge d'autres problèmes de santé dans 51,6% des cas. La prescription d'arrêts de travail concernait 9,3% des consultations (contre 14,7% d'arrêts de travail pour les femmes de la même tranche d'âge). La durée de consultation dépassait de 15,40% les autres consultations d'ECOGEN. Les médecins femmes étaient plus sollicitées que les hommes par les patientes enceintes ou en post-partum que par les autres patientes de la même tranche d'âge. Ceci était également le cas pour les médecins de moins de 50 ans. L'étude ECOGEN appliquée aux consultations des femmes enceintes ou en post-partum permet de mieux décrire l'activité du médecin généraliste et de montrer l'intérêt de la prise en charge globale de ces patientes en médecine générale.ROUEN-BU Médecine-Pharmacie (765402102) / SudocSudocFranceF

Single crystal growth, crystal structure and surface characterisation of the binary phase Al45Cr7.

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A new ternary compound with the BGa8Ir4 structure type in the Al-Au-Ir system

International audienceFollowing the recent determination of the Al3AuIr structure, a new ternary phase has been identified in the Al-Au-Ir phase diagram. It has a chemical composition Al 9 (Au;Ir)4 with an apparently low gold content. Its crystal structure has been determined with single-crystal X-ray diffraction. The new compound crystallizes in the tetragonal crystal system and has been successfully solved in space group I4 1/acd (Pearson symbol tI104) with lattice parameters a = 8.6339 (2) and c = 21.8874 (7) Å. Atomic environments are described as well as similarities with the BGa8Ir4 compound

Bronchial thermoplasty : a new therapeutic option for the treatment of severe, uncontrolled asthma in adults

Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of deterioration and hospitalisation in the days following the treatment. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based therapy, the overall evaluation of risk-benefit is unlike that of pharmaceutical products; safety aspects, regulatory requirements, study design and effect size assessment may be unfamiliar. The mechanisms of action and optimal patient selection need to be addressed in further rigorous clinical and scientific studies. Bronchial thermoplasty fits in perfectly with the movement to expand personalised medicine in the field of chronic airway disorders. This is a device-based complimentary asthma treatment that must be supported and developed in order to meet the unmet needs of modern severe asthma management. The mechanisms of action and the type of patients that benefit from bronchial thermoplasty are the most important challenges for bronchial thermoplasty in the future

Probing the growth window of LaVO₃ perovskites thin films elaborated using magnetron co-sputtering

LaVO3 is a promising material for tuning and improving solar cell performances when modifying the La/V stoichiometry. However, the production of LaVO3 thin films still requires a complex process (MBE, PLD), and the growth window of LaVO3 structure in terms of La/V ratio, already defined in the literature using hybrid-MBE is not determined for elaboration based on magnetron co-sputtering of both vanadium and lanthanum targets followed by an external reducing annealing that we use here. La/V ratio has been varied from 0.52 to 1.68 by changing the power applied to the vanadium target in order to synthesize films with different La/V ratios. The off-stoichiometry growth window has been investigated by complementary methods (XRD, XPS, FTIR and TEM). X-ray diffraction highlights the LaVO3 structure for all the films. For La-rich samples (La/V ratio andgt;1.2), the formation of lanthanum oxide La2O3 is observed at the top surface and interface with the substrate, according to XPS, FTIR and TEM investigations. On the other hand, for V-rich samples, only a slight modification of the structure is observed below the La/V ratio = 0.6; with the presence of a new IR vibration mode corresponding to a small contribution of vanadium oxide(s) present in volume. Our study allows a better definition of the LaVO3 growth window in terms of La/V ratio, estimated from 0.6 to 1.2. © 201

Role of self-irradiation defects on the ageing of 239PuCoGa5

6 pages, 18 referencesInternational audienceLow-temperature accumulation and annealing experiments, in conjunction with electrical resistivity and critical current density measurements, were used to study the ageing of the actinide superconductor PuCoGa5. These measurements reveal that 2-nm sized non-superconducting point-like regions are the main damage formed during room temperature ageing; smaller point-like defect were irrelevant to transport properties. Defect sizes and densities deduced from experiment agree with Transmission Electron Micoscopy observations

Direct observation of phase coherence in 3-<b>k</b> magnetic configurations

International audienceWe report the observation by neutron diffraction of phase coherent Bragg reflections in a multi-k magnetic configuration with a spatial periodicity outside the conventional scattering cross-section. The peaks, which exist in the 3-k state of UAs0.8Se0.2, display long-range order with a wavevector dependence characteristic of a magnetic interaction. The results confirm the long-range order and temperature dependence reported in an earlier study of similar peaks in this material using x-ray resonant scattering by (a) the non-trivial extension to the technique of neutron diffraction, and (b) the observation of similar 3-k phase-coherent reflections in other samples by x-ray resonant scattering. The importance of the neutron diffraction results lies primarily in the fact that magnetic neutron diffraction is well established as a weak probe operating on thermodynamic time scales. This alleviates concern that the rapid (10-15 - 10-14 s), strong interaction, characteristic of the resonant x-ray technique, is imaging a transient or non-equilibrium configuration. Likewise, the extension of the x-ray resonant scattering results to other samples establishes the generality of this effect. The enigma of how to understand the observed diffraction, which appears to lie strictly outside both the conventional neutron and x-ray scattering cross sections, remains