23,861 research outputs found
The design and content of the HALCyon qualitive study: a qualitive sub-study of the National Study of Health and Development and the Hertfordshire Cohort Study.:CLS Working Paper 2011/5
Self-reported pain severity is associated with a history of coronary heart disease
This study was funded by Arthritis Research UK (grant number: 17292).Peer reviewedPublisher PD
Conservation evo-devo: preserving biodiversity by understanding its origins
Unprecedented rates of species extinction increase the urgency for effective conservation biology management practices. Thus, any improvements in practice are vital and we suggest that conservation can be enhanced through recent advances in evolutionary biology, specifically advances put forward by evolutionary developmental biology (i.e., evo-devo). There are strong overlapping conceptual links between conservation and evo-devo whereby both fields focus on evolutionary potential. In particular, benefits to conservation can be derived from some of the main areas of evo-devo research, namely phenotypic plasticity, modularity and integration, and mechanistic investigations of the precise developmental and genetic processes that determine phenotypes. Using examples we outline how evo-devo can expand into conservation biology, an opportunity which holds great promise for advancing both fields
Modelling a two-dimensional spatial distribution of mycotoxin concentration in bulk commodities to design effective and efficient sample selection strategies
Mycotoxins in agricultural commodities are a hazard to human and animal health.
Their heterogeneous spatial distribution in bulk storage or transport makes it
particularly difficult to design effective and efficient sampling plans. There
has been considerable emphasis on identifying the different sources of
uncertainty associated with mycotoxin concentration estimations, but much less
on identifying the effect of the spatial location of the sampling points. This
study used a two-dimensional statistical modelling approach to produce detailed
information on appropriate sampling strategies for surveillance of mycotoxins in
raw food commodities. The emphasis was on deoxynivalenol (DON) and ochratoxin A
(OTA) in large lots of grain in storage or bulk transport. The aim was to
simulate a range of plausible distributions of mycotoxins in grain from a set of
parameters characterising the distributions. For this purpose, a model was
developed to generate data sets which were repeatedly sampled to investigate the
effect that sampling strategy and the number of incremental samples has on
determining the statistical properties of mycotoxin concentration. Results
showed that, for most sample sizes, a regular grid proved to be more consistent
and accurate in the estimation of the mean concentration of DON, which suggests
that regular sampling strategies should be preferred to random sampling, where
possible. For both strategies, the accuracy of the estimation of the mean
concentration increased significantly up to sample sizes of 40-60 (depending on
the simulation). The effect of sample size was small when it exceeded 60 points,
which suggests that the maximum sample size required is of this order. Similar
conclusions about the sample size apply to OTA, although the difference between
regular and random sampling was small and probably negligible for most sample
sizes
Modeling the adoption and use of social media by nonprofit organizations
This study examines what drives organizational adoption and use of social
media through a model built around four key factors - strategy, capacity,
governance, and environment. Using Twitter, Facebook, and other data on 100
large US nonprofit organizations, the model is employed to examine the
determinants of three key facets of social media utilization: 1) adoption, 2)
frequency of use, and 3) dialogue. We find that organizational strategies,
capacities, governance features, and external pressures all play a part in
these social media adoption and utilization outcomes. Through its integrated,
multi-disciplinary theoretical perspective, this study thus helps foster
understanding of which types of organizations are able and willing to adopt and
juggle multiple social media accounts, to use those accounts to communicate
more frequently with their external publics, and to build relationships with
those publics through the sending of dialogic messages.Comment: Seungahn Nah and Gregory D. Saxton. (in press). Modeling the adoption
and use of social media by nonprofit organizations. New Media & Society,
forthcomin
Groundwater seepage landscapes from distant and local sources in experiments and on Mars
© 2014 Author(s). Valleys with theater-shaped heads can form due to the seepage of groundwater and as a result of knickpoint (waterfall) erosion generated by overland flow. This ambiguity in the mechanism of formation hampers the interpretation of such valleys on Mars, particularly since there is limited knowledge of material properties. Moreover, the hydrological implications of a groundwater or surface water origin are important for our understanding of the evolution of surface features on Mars, and a quantification of valley morphologies at the landscape scale may provide diagnostic insights on the formative hydrological conditions. However, flow patterns and the resulting landscapes produced by different sources of groundwater are poorly understood. We aim to improve the understanding of the formation of entire valley landscapes through seepage processes from different groundwater sources that will provide a framework of landscape metrics for the interpretation of such systems. We study groundwater seepage from a distant source of groundwater and from infiltration of local precipitation in a series of sandbox experiments and combine our results with previous experiments and observations of the Martian surface. Key results are that groundwater flow piracy acts on valleys fed by a distant groundwater source and results in a sparsely dissected landscape of many small and a few large valleys. In contrast, valleys fed by a local groundwater source, i.e., nearby infiltration, result in a densely dissected landscape. In addition, valleys fed by a distant groundwater source grow towards that source, while valleys with a local source grow in a broad range of directions and have a strong tendency to bifurcate, particularly on flatter surfaces. We consider these results with respect to two Martian cases: Louros Valles shows properties of seepage by a local source of groundwater and Nirgal Vallis shows evidence of a distant source, which we interpret as groundwater flow from Tharsis
Effects of asymmetry on the dynamic stability of aircraft
The oblique wing concept for transonic aircraft was proposed to reduce drag. The dynamic stability of the aircraft was investigated by analytically determining the stability derivatives at angles of skew ranging from 0 and 45 deg and using these stability derivatives in a linear analysis of the coupled aircraft behavior. The stability derivatives were obtained using a lifting line aerodynamic theory and found to give reasonable agreement with derivatives developed in a previous study for the same aircraft. In the dynamic analysis, no instability or large changes occurred in the root locations for skew angles varying from 0 to 45 deg with the exception of roll convergence. The damping in roll, however, decreased by an order of magnitude. Rolling was a prominent feature of all the oscillatory mode shapes at high skew angles
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