Influence of Process Parameters and Responses on Performance of CNC Machine Turning Operation by using Multiple Regression Method

Influence of process parameters and responses on performance of CNC machine turning operation on EN-31 steel material in turning operations. This study aims at determining the factors and their interaction that may affect the responses. The response such as surface finish is greatly influenced by factors such as speed, feed rate and depth of cut. Multiple regression method is used to analyze the performance of process parameter on response such as surface finish rate is done on CNC lathe on EN31 sample. Hence, multiple regression model for surface finish has been developed, as a function of spindle speed, feed rate and depth of cut.. It was concluded that surface finish is highly dependent on spindle speed. DOI: 10.17762/ijritcc2321-8169.150518

Supporting survivors of sexual violence:protocol for a mixed methods, co-research study of the role, funding and commissioning of specialist services provided by the voluntary sector in England

Abstract Introduction The voluntary sector provides a range of specialist services to survivors of sexual violence, many of which have evolved from grass roots organisations responding to unmet local needs. However, the evidence base is poor in terms of what services are provided to which groups of survivors, how voluntary sector specialist (VSS) services are organised and delivered and how they are commissioned. This will be the first national study on the role of the voluntary sector in supporting survivors in England. Methods and analysis This study uses an explanatory sequential naturalistic mixed-methods design with two stages. For stage 1, two national surveys of providers’ and commissioners’ views on designing and delivering VSS services will facilitate detailed mapping of service provision and commissioning in order to create a taxonomy of VSS services. Variations in the national picture will then be explored in stage 2 through four in-depth, qualitative case studies using the critical incident technique to explain the observed variations and understand the key contextual factors which influence service provision. Drawing on theory about the distinctive service contribution of the voluntary sector, survivors will be involved as co-researchers and will play a central role in data collection and interpretation. Ethics and dissemination Ethical approval has been granted by the University of Birmingham research ethics committee for stage 1 of the project. In line with the sequential and co-produced study design, further applications for ethical review will be made in due course. Dissemination activities will include case study and end-of-project workshops; good practice guides; a policy briefing; project report; bitesize findings; webinars; academic articles and conference presentations. The project will generate evidence about what survivors want from and value about services and new understanding about how VSS services should be commissioned and provided to support survivors to thrive in the long term

Rumen flukes in ruminants

<p>Rumen fluke of ruminants is commonly known as Paramphistomes. It has other synonyms like amphistomes, stomach fluke and conical flukes. Paramphistomes are parasites that mostly infect sheep and cattle. The flukes are often found in small numbers but only seriously affect livestock under certain conditions, in heavy infections, and in certain growth stages. Adult flukes in the rumen or reticulum, for instance, are not known to cause clinical disease. On the other hand, severe infections have been known to harm the rumen. Severe illnesses and even death can result from heavy infections of the upper small intestine with immature flukes. The adult parasites are pear-shaped, pink or red, up to 15 mm long generally found in rumen and immature forms are 1–3 mm long and seen in the duodenum.</p&gt

Aspergillosis in poultry

<p>Avian Aspergillosis is the major mycotic non-contagious disease of birds. It is also known as brooder pneumonia. It is mainly the disease of respiratory system affecting domestic poultry, wild birds and zoo birds. This is considered as disease of typical mishandling of birds mainly backyard and commercial poultry. The aspergillosis is mainly caused by Aspergillus fumigatus fungus, however other species such as A. flavus, A. niger, A. nidulans, and A. terreus may also be isolated from cases of aspergillosis in birds (occasionally in mixed infections).</p&gt

Synthesis and biological evaluation of 4-styrylcoumarin derivatives as inhibitors of TNF-α and IL-6 with anti-tubercular activity

A series of 4-styrylcoumarin have been synthesized by Knoevenagel condensation between substituted 4-methylcoumarin-3-carbonitrile and different heterocyclic or aromatic aldehydes. 4-Methylcoumarin-3-carbonitrile has been synthesized by the base catalyzed reaction between substituted 2-hydroxyacetophenone and ethyl cyanoacetate. The structures of the newly synthesized compounds were confirmed by 1H NMR, IR and mass spectral analysis. All the compounds were evaluated for their anti-inflammatory activity (against TNF-α and IL-6) and anti-tubercular activity. Compounds 6a, 6h and 6j exhibited promising activity against IL-6 with 72–87% inhibition and compound 6v showed potent activity against TNF-α with 73% inhibition at 10 μM concentration. Whereas compounds 6n, 6o, 6r and 6u showed very good anti-tubercular activity against Mycobacterium tuberculosis H37Rv strain at <6.25 μM