Effect of Auxins on Shoot and Root Growth in an Endangered Medicinal Plant Guggal [Commiphora wightii (Arnott.) Bhand.]

An investigation was carried out to study the effect of IBA and NAA on vegetative propagation of guggal[Commiphora wightii (Arnott.) Bhand.] through cuttings, at Navsari Agricultural University, Navsari. The experiment consists of ten treatments: IBA, NAA and their combination, each at 2000, 4000 and 6000 mg l-1along with control, replicated thrice. Ten cuttings per each treatment and per replication were planted. Planting media used were: sand, soil and vermicompost, in 2:1:1 ratio. Cuttings were dipped for five minutes in solutions of IBA, NAA and their combinations. Cuttings treated with 4000 mg l-1 IBA proved to be the best for shoot and root responses, viz., days taken to first sprouting (11.67 days), number of shoots per cutting (10.27), number of leaves in the longest shoot (44.07), length of longest shoot (51.69cm), diameter of the longest shoot (4.40mm), rooting percentage (61.19), number of primary roots per cutting (15.01), length of the longest primary root (26.36cm), and number of secondary roots (22.37) and length of the longest secondary root (21.40cm) per cutting. It was concluded that IBA @ 4000 mg l-1 was most effective for obtaining maximum shoot and root growth

Time-delayed models of gene regulatory networks

We discuss different mathematical models of gene regulatory networks as relevant to the onset and development of cancer. After discussion of alternativemodelling approaches, we use a paradigmatic two-gene network to focus on the role played by time delays in the dynamics of gene regulatory networks. We contrast the dynamics of the reduced model arising in the limit of fast mRNA dynamics with that of the full model. The review concludes with the discussion of some open problems

The Rumsfeld Effect: The unknown unknown

A set of studies tested whether people can use awareness of ignorance to provide enhanced test consistency over time if they are allowed to place uncertain items into a “don’t know” category. For factual knowledge this did occur, but for a range of other forms of knowledge relating to conceptual knowledge and personal identity, no such effect was seen. Known unknowns would appear to be largely restricted to factual kinds of knowledge

The impact of COVID-19 on provision of UK audiology services & on attitudes towards delivery of telehealth services

Objective To (i) identify the impact of COVID-19 on provision of UK audiology services across sectors (ii) compare teleaudiology service provision between private and public sectors before and after the introduction of restrictions and (iii) identify barriers to teleaudiology delivery amongst UK hearing care professionals in both sectors. Design A mixed-methods cross-sectional survey study design. Responses to the structured questionnaire were analysed using descriptive and non-parametric statistics. Study Sample UK based hearing care professionals (HCP) (n = 323) completed the survey (218 public sector; 89 private sector). Results Changes in working patterns varied greatly between different sectors, with 61% of national employed and 26% of independent HCPs being furloughed, compared with 1% in the public sector. Use of telehealth was under-utilised across all sectors and groups in UK hearing healthcare, despite 92% of public and 75% of private HCPs reporting feeling comfortable conducting remote consultations. Conclusion This study highlights a variation in teleaudiology adoption and key barriers across sector in the UK. A collaborative approach between hearing device manufacturers, research centres, HCPs and professional bodies is required for the creation of targeted guidance and training materials according to sector, to support clinicians in effective teleaudiology provision

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPTLC METHOD FOR ESTIMATION OF SWERTIAMARIN IN BULK AND DOSAGE FORM

Objective: In the present study a novel stability-indicating high-performance thin-layer chromatography (HPTLC) method for quantitative determination of Swertiamarin (SW) in bulk drug and formulation has been developed and validated as per ICH guideline Q2 (R1) for global acceptance of standardized herbal formulations. Methods: HPTLC method is developed and validated using solvent ethyl acetate: ethanol: chloroform (3:2.5:4.5 v/v/v) (Rf of SW 0.65±0.04) in the absorbance mode at 243 nm. Various forced degradation conditions were used to check degradation of drug. Results: The method showed a good linear relationship (r2 = 0.9990) in the concentration range 200-700 ng per spot. It was found to be linear, accurate, precise and specific. Conclusion: It can be applied for quality control as well as for stability testing of different dosage forms containing swertiamarin. The developed method is validated as per ICH guideline Q2(R1) for global acceptance of standardized herbal formulations

American power and identities in the age of Obama

Although the election of Barack Obama to the US presidency represents a landmark event in the history of that country, questions remain over its broader political significance. What is the likelihood of Obama's foreign and national security policies differing fundamentally from those of the Bush administrations Does Obama's election signal a post-racial phase in American national life What are the factors that suggest opportunities to change and expand American identities as opposed to those that limit Obama's sphere of action This article introduces the special issue and suggests that although Obama's room for manoeuvre is limited by legacies inherited from the Bush administration, Obama's own appointments to high office as well as other actions, despite the availability of alternative courses, indicate that he is not the transformational president he claimed to be. American identities, therefore, are deeply embedded and remain heavily imbued with racial, religious and imperial features

The electrorheology of suspensions consisting of Na-Fluorohectorite synthetic clay particles in silicon oil

Under application of an electric field greater than a triggering electric field $E_c \sim 0.4$ kV/mm, suspensions obtained by dispersing particles of the synthetic clay fluoro-hectorite in a silicon oil, aggregate into chain- and/or column-like structures parallel to the applied electric field. This micro-structuring results in a transition in the suspensions' rheological behavior, from a Newtonian-like behavior to a shear-thinning rheology with a significant yield stress. This behavior is studied as a function of particle volume fraction and strength of the applied electric field, $E$. The steady shear flow curves are observed to scale onto a master curve with respect to $E$, in a manner similar to what was recently found for suspensions of laponite clay [42]. In the case of Na-fluorohectorite, the corresponding dynamic yield stress is demonstrated to scale with respect to $E$ as a power law with an exponent $\alpha \sim 1.93$, while the static yield stress inferred from constant shear stress tests exhibits a similar behavior with $\alpha \sim 1.58$. The suspensions are also studied in the framework of thixotropic fluids: the bifurcation in the rheology behavior when letting the system flow and evolve under a constant applied shear stress is characterized, and a bifurcation yield stress, estimated as the applied shear stress at which viscosity bifurcation occurs, is measured to scale as $E^\alpha$ with $\alpha \sim 0.5$ to 0.6. All measured yield stresses increase with the particle fraction $\Phi$ of the suspension. For the static yield stress, a scaling law $\Phi^\beta$, with $\beta = 0.54$, is found. The results are found to be reasonably consistent with each other. Their similarities with-, and discrepancies to- results obtained on laponite-oil suspensions are discussed

Authorship pattern and growth of scholar contributions for PHFI: A Bibliometric Analysis

The purpose of this research study is to identify the authorship patterns and degree of collaboration and growth of Public health foundation of India in Public Health research related with a total of 1941 records of publications authored by 12523 authors during the period 2011– 2020 derived from SCOPUS database. Validation of determine chronological growth, authorship pattern, core sources for research communication, and encouragement of productivity by citations received, various indicators, and indices and bibliometric laws i.e. Authorship pattern, RGR, Dt, CAI, DC, Bradford’s Law of distributions, and more have been applied appropriately. Additionally, used deferent software of like ‘MS-Excel’ and ‘bibliometrix’ & ‘biblioshiny’ of R-Package software and VOSviwer software applied for detailed and reliable analysis. Evaluated data figured out Average yearly contribution 194 research however accounted Mean RGR(P) ‘0.34’; Mean Dt (P) ’2.74 reveals inconsistent growth of research output. Average of ‘Collaboration index’ (CI) ‘5.60’ A total Average yearly citations were received for research occurrence in the span with an average of 10.46, Prabhakaran. D., was published highest papers 260 and got received highest citation also 4958 and total link strength 1457. For PHFI and individual research scholars. PHFI has to make more effort to promote research and create quality culture, attention of developing better policies to enhance and enrich the research performance of individuals

A supernova remnant coincident with the slow X-ray pulsar AX J1845-0258

We report on Very Large Array observations in the direction of the recently-discovered slow X-ray pulsar AX J1845-0258. In the resulting images, we find a 5-arcmin shell of radio emission; the shell is linearly polarized with a non-thermal spectral index. We class this source as a previously unidentified, young (< 8000 yr), supernova remnant (SNR), G29.6+0.1, which we propose is physically associated with AX J1845-0258. The young age of G29.6+0.1 is then consistent with the interpretation that anomalous X-ray pulsars (AXPs) are isolated, highly magnetized neutron stars ("magnetars"). Three of the six known AXPs can now be associated with SNRs; we conclude that AXPs are young (~<10 000 yr) objects, and that they are produced in at least 5% of core-collapse supernovae.Comment: 4 pages, 1 embedded EPS file, uses emulateapj.sty. Accepted to ApJ Letter