A strategic needs assessment for Nottinghamshire

Peter Murphy, Kirsten Greenhalgh and Craig Parkin from Nottingham Trent University, University of Nottingham and Nottinghamshire Fire and Rescue Service, report on their joint project

Fire and rescue service reconfiguration: a case study in Nottinghamshire

The Fire Cover Review in Nottinghamshire arises out of the Integrated Risk Management Planning process introduced in the UK by the Fire and Rescue 2004 Act,. It is intended to provide the evidence and analysis for the reconfiguration of services and the future deployment of resources in in the short, medium and long terms. Any future reconfigurations of services must be based on contemporary and comprehensive risk assessments of the areas affected.(ODPM 2004). The need to undertake the review pre-dated the current financial crises, the general election and the need for significant reductions in public expenditure in the UK, although these circumstances made the review more challenging and politically sensitive. This paper evaluates the practical implementation of the Integrated Risk Management Planning process and the Fire Cover Review in Nottinghamshire to identify good practice and to generate recommendations for improving the process and its implementation

Heusler 4.0: Tunable Materials

Heusler compounds are a large family of binary, ternary and quaternary compounds that exhibit a wide range of properties of both fundamental and potential technological interest. The extensive tunability of the Heusler compounds through chemical substitutions and structural motifs makes the family especially interesting. In this article we highlight recent major developments in the field of Heusler compounds and put these in the historical context. The evolution of the Heusler compounds can be described by four major periods of research. In the latest period, Heusler 4.0 has led to the observation of a variety of properties derived from topology that includes: topological metals with Weyl and Dirac points; a variety of non-collinear spin textures including the very recent observation of skyrmions at room temperature; and giant anomalous Hall effects in antiferromagnetic Heuslers with triangular magnetic structures. Here we give a comprehensive overview of these major achievements and set research into Heusler materials within the context of recent emerging trends in condensed matter physics

Transport and Magnetic Properties of FexVse2 (x = 0 - 0.33)

We present our results of the effect of Fe intercalation on the structural, transport and magnetic properties of 1T-VSe2. Intercalation of iron, suppresses the 110K charge density wave (CDW) transition of the 1T-VSe2. For the higher concentration of iron, formation of a new kind of first order transition at 160K takes place, which go on stronger for the 33% Fe intercalation. Thermopower of the FexVSe2 compounds (x = 0 - 0.33), however do not show any anomaly around the transition. The intercalation of Fe does not trigger any magnetism in the weak paramagnetic 1T-VSe2, and Fe is the low spin state of Fe3+.Comment: 7 pages, 8 figures, 2 table

Acute phase protein levels in dogs with mast cell tumours and sarcomas

<p><b>Context:</b> The acute phase protein response is part of a non-specific and complex host response to inflammation. It occurs shortly after tissue injury and may be induced by a range of different causes, including infectious, inflammatory, neoplastic, traumatic or immunological disease. Although it was conventionally believed that APPs were exclusively hepatocyte derived, there is increasing evidence to support extra-hepatic generation in neoplastic and other disease states. In people, C-reactive protein (CRP) has been shown to be of value in identifying metastatic disease from primary renal tumours as well as showing promise for monitoring rejection of renal transplants. Serum CRP correlates with survival in colorectal cancer and oesophageal squamous cell carcinoma while serum amyloid A (SAA) concentrations correlate with cancer activity, stage and prognosis in gastric tumours. Recent immunohistochemical studies in people with oesophageal carcinoma suggest that tumour tissue may itself elaborate APP with a poorer survival and outcome associated with tumours elaborating higher levels of CRP. A similar association has been seen between alpha-1 acid glycoprotein (AGP) and colorectal tumours and ovarian carcinoma.</p> <p>As yet, studies regarding APP values in neoplastic conditions in dogs are limited, and many are non-specific. In veterinary patients, elevated levels of AGP have been identified in dogs with a range of tumours with localisation to liver and splenic tissue in one study. Another study found higher levels of AGP in dogs with non-specific tumours of grade III-IV based on the WHO Tumour Node Metastasis (TNM) scale and elevated serum AGP has been documented in non-specific tumour-bearing cats. Elevated CRP levels have been documented in both dogs and cats with lymphoma and serum CRP may be used as an indicator of complete remission status in dogs with multicentric lymphoma. Elevated levels of CRP, Haptoglobin (Hp) and SAA have been identified in dogs with mammary tumours, with significant increases over normal in the presence of metastatic disease, primary tumours greater than 5cm in diameter and those with ulceration.</p> <p>In this study we evaluated an APP profile using four APPs (CRP, Hp, SAA and AGP), in dogs with mast cell tumours (MCTs) and sarcomas to assess whether the APP profile would change in reflection of tumour presence; whether the extent of any change would correlate with tumour grade; and whether the changes would differ with tumour type.</p> <p><b>Approach:</b> Patients with naturally occurring MCTs and sarcomas presenting for staging and treatment were included if they met the study criteria. Criteria for inclusion were that the patient was not currently being treated with steroids, did not have a recent history of infectious or inflammatory disease other than the tumour, a definitive histological diagnosis was available and a full staging procedure was completed prior to surgery using standard oncological protocols to identify metastatic disease where present. Following surgical resection each tumour was submitted for full histological evaluation and grading to include assessment of the margins of excision. Cases were only enrolled in the study if blood sampling formed part of the clinical investigation and/or treatment, and where residual blood was available after diagnostic sampling which would otherwise have been disposed of as clinical waste. In brief, the CRP levels were determined by immunoturbidometric assay and Hp by means of haemoglobin binding capacity assay. SAA was measured with a commercial canine ELISA kit (TriDelta Development, Dublin, Ireland) and AGP was measured with a commercial radial immunodiffusion assay (J-Path Inc, Tokyo, Japan).</p> <p><b>Results:</b> All comparisons using continuous data were checked for normality and equality of variances and appropriate statistical tests were employed (student’s t test operationalised as a two-sample Welch’s test for samples of unequal sizes and variances, Mann-Whitney, Chi-square and Fishers exact tests as appropriate). In MCTs, the CRP and AGP were elevated above reference ranges, Hp showed no significant change and SAA dropped relative to the reference range. In sarcoma patients CRP, Hp and AGP were all elevated above reference ranges. None of the tumour grade differences were significant apart from SAA in sarcoma patients where values in grade 2 sarcoma were significantly higher than those in grade 1.</p> <p><b>Interpretation and notes of caution:</b> The numbers in our groups were small which compromises the validity of statistical evaluation so our results must be interpreted with caution. However some interesting relationships have emerged from the initial evaluation which suggests that APP profiles may have potential for screening in patients with neoplastic disease. For patients with MCTs, CRP and AGP levels would be expected to increase, with a concurrent drop in SAA levels. In sarcoma patients CRP, AGP and Hp can all be expected to increase. These initial results need to be evaluated in larger numbers of cases with naturally occurring disease to validate the findings, to assess whether the presence and extent of metastatic disease has a significant effect, and also to confirm whether the values alter after surgical resection of the primary tumour.</p> <p><b>Significance of findings:</b> If there are consistent and specific changes in APP profiles associated with different tumour types in dogs, as is the case with a wide range of cancers in humans, then there may be potential for APP profiles on routine blood samples to be used as indicators of disease, or where monitoring for recurrence. Whether they could also have potential for assessment of the presence of metastatic disease and prognosis as in people is unknown as yet.</p&gt

Temperature- and Bias-dependence of magnetoresistance in doped manganite thin film trilayer junctions

Thin film trilayer junction of La$$Sr$_{0.33}$MnO$_3$ - SrTiO$_3$ - La$_{0.67}$Sr$_{0.33}$MnO$_3$ shows a factor of 9.7 change in resistance, in a magnetic field around 100 Oe at 14K. The junction magnetoresistance is bias and temperature dependent. The energy scales associated with bias and temperature dependence are an order of magnitude apart. The same set of energies also determine the bias and temperature dependence of the differential conductance of the junction. We discuss these results in terms of metallic cluster inclusions at the junction-barrier interface.Comment: 3 pages, 4 figure

Better the Devil You Know: A User Study of Two CAPTCHAs and a Possible Replacement

CAPTCHAs are difficult for humans to use, causing frustration. Alternatives have been proposed, but user studies equate usability to solvability. We consider the user perspective to include workload and context of use. We assess traditional text-based CAPTCHAs alongside PlayThru, a 'gamified' verification mechanism, and NoBot, which uses face biometrics. A total of 87 participants were tasked with ticket-buying across three conditions: (1) all three mechanisms in comparison, and NoBot three times (2) on a laptop, and (3) on a tablet. A range of quantitative and qualitative measurements explored the user perspective. Quantitative results showed that participants completed reCAPTCHAs quickest, followed by PlayThru and NoBot. Participants were critical of NoBot in comparison but praised it in isolation. Despite reporting negative experiences with reCAPTCHAs, they were the preferred mechanism, due to familiarity and a sense of security and control. Although slower, participants praised NoBot's completion speeds, but regarded using personal images as invading privacy

"I don’t like putting my face on the Internet!": An acceptance study of face biometrics as a CAPTCHA replacement

Biometric technologies have the potential to reduce the effort involved in securing personal activities online, such as purchasing goods and services. Verifying that a user session on a website is attributable to a real human is one candidate application, especially as the existing CAPTCHA technology is burdensome and can frustrate users. Here we examine the viability of biometrics as part of the consumer experience in this space. We invited 87 participants to take part in a lab study, using a realistic ticket-buying website with a range of human verification mechanisms including a face biometric technology. User perceptions and accep- tance of the various security technologies were explored through interviews and a range of questionnaires within the study. The results show that some users wanted reassurance that their personal image will be protected or discarded af- ter verifying, whereas others felt that if they saw enough people using face biometrics they would feel assured that it was trustworthy. Face biometrics were seen by some par- ticipants to be more suitable for high-security contexts, and by others as providing extra personal data that had unac- ceptable privacy implications

Large planar Hall effect in bismuth thin films

The origin of the planar Hall effect (PHE) in various nonmagnetic semimetals has become a subject of considerable interest, especially in regard to the chiral anomaly that several of these semimetals exhibit. Here, we report a large PHE that exceeds several mΩ cm over a wide range of temperature T and magnetic field B in micron-thick single-crystalline bismuth thin films grown by molecular beam epitaxy techniques. The angular dependence of the PHE and the related anisotropic magnetoresistance (AMR) show complex behaviors as a function of B and T. At high temperatures and in modest magnetic fields, the PHE and AMR can be quantitatively explained by a semiclassical transport model based on the well-established elongated electron and hole pockets of the Fermi surface in bismuth. Although these results establish an anisotropic electronic orbital origin of the PHE, we find that when the electric current is oriented along the binary axis of bismuth, the PHE and AMR behaviors can be well described by a model based on the chiral anomaly in Weyl or Dirac semimetals. However, this model cannot account for these behaviors when the current is rather oriented along the bisectrix axis. Thus, the anisotropy of the PHE is a useful test to check on the validity of the chiral anomaly in semimetals