The Krull dimension of power series rings over non-SFT rings

AbstractLet R be a commutative ring with identity. We show that the Krull dimension of the power series ring R〚X〛 can be uncountably infinite, i.e., there exists an uncountably infinite chain of prime ideals in R〚X〛, even if dimR is finite. In fact, we show that dimR〚X〛 is uncountably infinite if R is a non-SFT ring, which is an improvement of Arnold’s result

Proteomic Analysis to Identify Tightly-Bound Cell Wall Protein in Rice Calli.

Rice is a model plant widely used for basic and applied research programs. Plant cell wall proteins play key roles in a broad range of biological processes. However, presently, knowledge on the rice cell wall proteome is rudimentary in nature. In the present study, the tightly-bound cell wall proteome of rice callus cultured cells using sequential extraction protocols was developed using mass spectrometry and bioinformatics methods, leading to the identification of 1568 candidate proteins. Based on bioinformatics analyses, 389 classical rice cell wall proteins, possessing a signal peptide, and 334 putative non-classical cell wall proteins, lacking a signal peptide, were identified. By combining previously established rice cell wall protein databases with current data for the classical rice cell wall proteins, a comprehensive rice cell wall proteome, comprised of 496 proteins, was constructed. A comparative analysis of the rice and Arabidopsis cell wall proteomes revealed a high level of homology, suggesting a predominant conservation between monocot and eudicot cell wall proteins. This study importantly increased information on cell wall proteins, which serves for future functional analyses of these identified rice cell wall proteins

Compton Scattering on the Deuteron in Baryon Chiral Perturbation Theory

Compton scattering on the deuteron is studied in the framework of baryon chiral perturbation theory to third order in small momenta, for photon energies of order the pion mass. The scattering amplitude is a sum of one- and two-nucleon mechanisms with no undetermined parameters. Our results are in good agreement with existing experimental data, and a prediction is made for higher-energy data being analyzed at SAL.Comment: 39 pages LaTeX, 19 figures (uses epsf

Early-phase clinical trial eligibility and response evaluation criteria for refractory, relapsed, or progressive neuroblastoma: A consensus statement from the National Cancer Institute Clinical Trials Planning Meeting

Consensus criteria; Early phase; NeuroblastomaCriteris de consens; Fase inicial; NeuroblastomaCriterios de consenso; Fase inicial; NeuroblastomaBackground International standardized criteria for eligibility, evaluable disease sites, and disease response assessment in patients with refractory, progressive, or relapsed high-risk neuroblastoma enrolled in early-phase clinical trials are lacking. Methods A National Cancer Institute–sponsored Clinical Trials Planning Meeting was convened to develop an international consensus to refine the tumor site eligibility criteria and evaluation of disease response for early-phase clinical trials in children with high-risk neuroblastoma. Results Standardized data collection of patient and disease characteristics (including specified genomic data), eligibility criteria, a definition of evaluable disease, and response evaluations for primary and metastatic sites of disease were developed. Eligibility included two distinct patient groups: progressive disease and refractory disease. The refractory disease group was subdivided into responding persistent disease and stable persistent disease to better capture the clinical heterogeneity of refractory neuroblastoma. Requirements for defining disease evaluable for a response assessment were provided; they included requirements for biopsy to confirm viable neuroblastoma and/or ganglioneuroblastoma in those patients with soft tissue or bone disease not avid for iodine-123 meta-iodobenzylguanidine. Standardized evaluations for response components and time intervals for response evaluations were established. Conclusions The use of international consensus eligibility, evaluability, and response criteria for early-phase clinical studies will facilitate the collection of comparable data across international trials and promote more rapid identification of effective treatment regimens for high-risk neuroblastoma.National Cancer Institute Pediatric and Adolescent Solid Tumor Steering Committee; Alex's Lemonade Stand Foundation for Childhood Cancer; Ben Towne Foundation; EVAN Foundation; Cancer Research UK Institute of Cancer Research, Grant/Award Number C347/A15403; National Institute for Health Research Research Methods Programme/Institute of Cancer Research Biomedical Research Centre

A deeply embedded young protoplanetary disk around L1489 IRS observed by the submillimeter array

Circumstellar disks are expected to form early in the process that leads to the formation of a young star, during the collapse of the dense molecular cloud core. It is currently not well understood at what stage of the collapse the disk is formed or how it subsequently evolves. We aim to identify whether an embedded Keplerian protoplanetary disk resides in the L1489 IRS system. Given the amount of envelope material still present, such a disk would respresent a very young example of a protoplanetary disk. Using the Submillimeter Array (SMA) we have observed the HCO$^+$ $J=$ 3--2 line with a resolution of about 1$''$. At this resolution a protoplanetary disk with a radius of a few hundred AUs should be detectable, if present. Radiative transfer tools are used to model the emission from both continuum and line data. We find that these data are consistent with theoretical models of a collapsing envelope and Keplerian circumstellar disk. Models reproducing both the SED and the interferometric continuum observations reveal that the disk is inclined by 40$^\circ$ which is significantly different to the surrounding envelope (74$^\circ$). This misalignment of the angular momentum axes may be caused by a gradient within the angular momentum in the parental cloud or if L1489 IRS is a binary system rather than just a single star. In the latter case, future observations looking for variability at sub-arcsecond scales may be able to constrain these dynamical variations directly. However, if stars form from turbulent cores, the accreting material will not have a constant angular momentum axis (although the average is well defined and conserved) in which case it is more likely to have a misalignment of the angular momentum axes of the disk and the envelope.Comment: 11 pages, 13 figures, accepted by A&