1,061 research outputs found

    Hypervector Spaces Based on Intersectional Soft Sets

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    The notion of int-soft subfields, int-soft algebras over int-soft subfields, and int-soft hypervector spaces are introduced, and their properties and characterizations are considered. In connection with linear transformations, int-soft hypervector spaces are discussed

    Fungal endophytes inhabiting mountain-cultivated ginseng (Panax ginseng Meyer) : diversity and biocontrol activity against ginseng pathogens

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    Fungal endophytes isolated from mountain-cultivated ginseng (MCG, Panax ginseng Meyer) were explored for their diversity and biocontrol activity against ginseng pathogens (Alternaria panax, Botrytis cinerea, Cylindrocarpon destructans, Pythium sp. and Rhizoctonia solani). A total of 1,300 isolates were isolated from three tissues (root, stem and leaf) from MCGs grown in 24 different geographic locations in Korea. In total, 129 different fungal isolates were authenticated by molecular identification based on internal transcribed spacer (ITS) sequences. The fungal endophytes belonged to Ascomycota (81.7%), Basidiomycota (7.08%), Zygomycota (10%) and Unknown (1.15%), with 59 genera. Analysis of diversity indices across sampling sites suggested species abundance as a function of geographical and environmental factors of the locations. Shannon diversity index and richness in the different tissues revealed that root tissues are colonized more than stem and leaf tissues, and also certain fungal endophytes are tissue specific. Assessment of the ethyl acetate extracts from 129 fungal isolates for their biocontrol activity against 5 ginseng pathogens revealed that Trichoderma polysporum produces the antimcriobial metabolite against all the pathogens. This result indicates the promise of its potential usage as a biocontrol agent

    Coderivations of Ranked Bigroupoids

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    The notion of (co)derivations of ranked bigroupoids is discussed by Alshehri et al. (in press), and their generalized version is studied by Jun et al. (under review press). In particular, Jun et al. (under review press) studied coderivations of ranked bigroupoids. In this paper, the generalization of coderivations of ranked bigroupoids is discussed. The notion of generalized coderivations in ranked bigroupoids is introduced, and new generalized coderivations of ranked bigroupoids are obtained by combining a generalized self-coderivation with a rankomorphism. From the notion of (X,∗,&)-derivation, the existence of a rankomorphism of ranked bigroupoids is established

    The Physico-Chemical and Microbiological Water Quality of the Artificial Lake Keumgang

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    This study was performed to investigate the changing encironment of Keum River after the construction of the floodgate at the mouth of Keum River. Samples were taken from the surface wateres at 3 stations near the floodgate of the artificial lake Keumgang to measure the physico-chemikcal and microbiological water qualities from May, 2001 to April, 2002. The results were as follows; water temperature ranged from 2 to 28℃, and pH values caried from 7.5 to 9.1 respectively. The dissolced oxygen contents and COD of each station varied from 7.13 to 14.10 mg l⁻¹ and from 5.2 to 9.4 mg l⁻¹resoectively. And total nitrogen and total phosphate values varied from 0.99 to 3.15 mg l⁻¹, and from 0.01 to 0.12 mg l⁻¹ during survey periods,which meant the sampling stations have set in eutrophic level The population density of heterotrophic bacteria ranged from 0.4±0.1 x 103 cfu ml⁻¹ to 3.5±0.6 x 10³cfu ml⁻¹ for during survey periods. The population densities of physiological groups of aerobic bacteria ranged from 2.0±1.0 x 10² to 1.7±0.2 x 10³ cfu ml⁻¹ for amylolytic bacteria, from 0.3±0.1 x 10² to 1.3±+0.5 x 10³ cfu ml⁻¹ for proteolytix bacteria, from 0.2±0.1 x 10³ to 4.9±1.3 x 10³ cfu ml⁻¹ for lipolytic bacteria, and from 0.2±0.1 x 10² to 2.7±0.7 x 10³ cfu ml⁻¹ for cellulolytic bacteria during survey periods, respectively. Among the measured numbers of physiological groups of bacteria, lipolytic bacteria showed the highest population density. Howecer, the numbers of amylolytic, pyoteolytic, and cellulolylic bacteria showed the similar tendency.Article信州大学山地水環境教育研究センター研究報告 2: 57-61(2004)departmental bulletin pape

    Orphan nuclear receptor Nurr1 induces neuron differentiation from embryonic cortical precursor cells via an extrinsic paracrine mechanism

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    AbstractNurr1 is an orphan nuclear receptor-type transcription factor (TF) that plays critical roles in midbrain dopamine neuron development. This study demonstrated a novel role for Nurr1 in neuronal/astrocytic differentiation of neural precursor (NP) cells isolated from rat embryonic cortices: overexpression of this TF promoted NP cell differentiation towards neurons at the expense of astrocytic differentiation. Single cell-based lineage analyses and experiments using co-cultures revealed that Nurr1 elicited its neurogenic role in an extrinsic paracrine manner. We defined diffusible factors and downstream neurogenic TFs responsible for the Nurr1-mediated neuronal differentiation

    Anti-diabetic effect of Cyclo-His-Pro (CHP)-enriched yeast hydrolysate in streptozotocin-induced diabetic mice

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    The present study was designed to investigate the hypoglycemic effects of the daily oral dose of 0.50 to 0.75 g/kg of yeast hydrolysate (YH) containing high Cyclo-His-Pro (51.0 mg CHP/g YH) on normal and streptozotocin (STZ)-induced diabetic rats for 14 days. In STZ-induced diabetic rats, after administrations of the YH for 14 days, the body weight gain was significantly increased in dose dependent manner, and the plasma glucose levels were decreased approximately (60%) as compared to the STZ induced diabetic control group. Glucose level showed significant differences between the diabetic control (DC) and the YH administered groups in oral glucose tolerance test (OGTT) (P<0.05). Results of the OGTT showed a significant decrease in the area under curve (AUC) value of YH supplemented groups as compared to the DC group. The present data suggests that the CHP-enriched YH has potential anti-diabetic effect, which can help in the cure and management of diabetes.Keywords: Yeast hydrolysate, Cyclo-His-Pro (CHP), diabetes, streptozotocin.African Journal of Biotechnology Vol. 12(35), pp. 5473-547

    Downregulation of protein kinase CK2 activity induces age-related biomarkers in C. elegans

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    Studies show that a decrease in protein kinase CK2 (CK2) activity is associated with cellular senescence. However, the role of CK2 in organism aging is still poorly understood. Here, we investigated whether protein kinase CK2 (CK2) modulated longevity in Caenorhabditis elegans. CK2 activity decreased with advancing age in the worms. Knockdown of kin-10 (the ortholog of CK2 beta) led to a short lifespan phenotype and induced age-related biomarkers, including retardation of locomotion, decreased pharyngeal pumping rate, increased lipofuscin accumulation, and reduced resistance to heat and oxidative stress. The long lifespan of age-1 and akt-1 mutants was significantly suppressed by kin-10 RNAi, suggesting that CK2 acts downstream of AGE-1 and AKT-1. Kin-10 knockdown did not further shorten the short lifespan of daf-16 mutant worms but either decreased or increased the transcriptional activity of DAF-16 depending on the promoters of the target genes, indicating that CK2 is an upstream regulator of DAF-16 in C. elegans. Kin-10 knockdown increased production of reactive oxygen species (ROS) in the worms. Finally, the ROS scavenger N-acetyl-L-cysteine significantly counteracts the lifespan shortening and lipofuscin accumulation induced by kin-10 knockdown. Therefore, the present results suggest that age-dependent CK2 downregulation reduces longevity by associating with both ROS generation and the AGE-1-AKT-1-DAF-16 pathway in C. elegans. © Copyright 2017 Elsevier B.V., All rights reserved.1111sci

    Bezoar-induced Small Bowel Obstruction

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    Purpose: The aim of this study was to observe the clinical features of a bezoar-induced small bowel obstruction and to in-vestigate the role of abdominal computed tomography (CT) in establishing the diagnosis. Methods: We retrospectively reviewed 20 cases of bezoar-induced small bowel obstruction in our hospital from 1996 to 2010. Results: Thirteen patients (65%) had a history of abdominal surgery. Nine patients (45%) were diagnosed with a bezoar before surgery, seven patients were diagnosed by using abdominal CT, and two patients were diagnosed with a small bowel series. Abdominal CT was performed in 15 patients, and the diagnostic accuracy was 47 % (7/15). Surgery revealed ten bezoars in the jejunum and 11 in the ileum. Two patients had bezoars found concurrently in the stomach. Spontaneous removal took place in two patients. An enterotomy and bezoar extraction was performed in 15 patients. Fragmentation and milking, a small bowel resection, and a Meckel’s diverticulectomy were performed in one patient each. Early operative treatment was possible (P = 0.036) once the bezoar had been diagnosed by using abdominal CT. There tended to be fewer postoperative complications in patients who were diagnosed with a bezoar by using abdominal CT, but the result was not statistically significant (P = 0.712). Conclusion: A preoperative diagnosis of bezoar-induced small bowel obstruction by using clinical features was difficult. Increased use of abdominal CT led to a more accurate diagnosis and to earlier surgery for bezoar-induced small bowel obstructions, thereby reducing the rate of complications
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