130 research outputs found
Problems of interpritation signs ans symbols in the process of crosscultural interaction
The article outlines the main differences between the sign and symbol. Examines various scientific approaches to the analysis of the essence of the character. The basic character traits. The attention is paid to the social nature of the origin of the symbol. Identifies the main problems faced by the communication. Discusses aspects of successful cross-cultural communication. Identifies the need for knowledge a reality for the successful sociokulturonoj mezkultutnom interaction.Π ΡΡΠ°ΡΡΠ΅ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ°Π·Π»ΠΈΡΠΈΡ ΠΌΠ΅ΠΆΠ΄Ρ Π·Π½Π°ΠΊΠΎΠΌ ΠΈ ΡΠΈΠΌΠ²ΠΎΠ»ΠΎΠΌ. ΠΠ½Π°Π»ΠΈΠ·ΠΈΡΡΡΡΡΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠ΅ Π½Π°ΡΡΠ½ΡΠ΅ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΠΊ Π°Π½Π°Π»ΠΈΠ·Ρ ΡΡΡΠ½ΠΎΡΡΠΈ ΡΠΈΠΌΠ²ΠΎΠ»Π°. Π Π°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ ΡΠΈΠΌΠ²ΠΎΠ»Π°. ΠΠΊΡΠ΅Π½ΡΠΈΡΡΠ΅ΡΡΡ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π½Π° ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎΠΌ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ΅ ΠΏΡΠΎΠΈΡΡ
ΠΎΠΆΠ΄Π΅Π½ΠΈΡ ΡΠΈΠΌΠ²ΠΎΠ»Π°. ΠΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ, Ρ ΠΊΠΎΡΠΎΡΡΠΌ ΡΡΠ°Π»ΠΊΠΈΠ²Π°ΡΡΡΡ ΡΡΠ°ΡΡΠ½ΠΈΠΊΠΈ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ. Π Π°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ Π°ΡΠΏΠ΅ΠΊΡΡ ΡΡΠΏΠ΅ΡΠ½ΠΎΠΉ ΠΊΡΠΎΡΡ-ΠΊΡΠ»ΡΡΡΡΠ½ΠΎΠΉ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΈ. ΠΠΏΡΠ΅Π΄Π΅Π»ΡΠ΅ΡΡΡ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ Π·Π½Π°Π½ΠΈΡ ΠΈΠ½ΠΎΠΉ ΡΠΎΡΠΈΠΎΠΊΡΠ»ΡΡΡΡΠ½ΠΎΠΉ ΡΠ΅Π°Π»ΡΠ½ΠΎΡΡΠΈ Π΄Π»Ρ ΡΡΠΏΠ΅ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΠΆΠΊΡΠ»ΡΡΡΡΠ½ΠΎΠ³ΠΎ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ
Control of the enlisted potential of the higher school: problems and the prospects
In the article the problems of control of the enlisted potential of higher school in connection with the renovation of normative lawful reports in the sphere of labor, formation and science are examined. Some problems in the sphere of control of cadreresources and the regulation of the labor of pedagogical workers in the system of higher education are determined. Are designated the prospects of introducing the effective contract and the reasons, which impede its introduction.Π Π°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ Π²ΠΎΠΏΡΠΎΡΡ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΊΠ°Π΄ΡΠΎΠ²ΡΠΌ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΠΎΠΌ Π²ΡΡΡΠ΅ΠΉ ΡΠΊΠΎΠ»Ρ Π² ΡΠ²ΡΠ·ΠΈ Ρ ΠΎΠ±Π½ΠΎΠ²Π»Π΅Π½ΠΈΠ΅ΠΌ Π½ΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΡΡ
ΠΏΡΠ°Π²ΠΎΠ²ΡΡ
Π°ΠΊΡΠΎΠ² Π² ΡΡΠ΅ΡΠ΅ ΡΡΡΠ΄Π°, ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ ΠΈ Π½Π°ΡΠΊΠΈ. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ Π½Π΅ΠΊΠΎΡΠΎΡΡΠ΅ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ Π² ΡΡΠ΅ΡΠ΅ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΊΠ°Π΄ΡΠΎΠ²ΡΠΌΠΈ ΡΠ΅ΡΡΡΡΠ°ΠΌΠΈ ΠΈ ΡΠ΅Π³ΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΡΡΠ΄Π° ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°Π±ΠΎΡΠ½ΠΈΠΊΠΎΠ² Π² ΡΠΈΡΡΠ΅ΠΌΠ΅ Π²ΡΡΡΠ΅Π³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ. ΠΠ±ΠΎΠ·Π½Π°ΡΠ΅Π½Ρ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Ρ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΠ°ΠΊΡΠ° ΠΈ ΠΏΡΠΈΡΠΈΠ½Ρ, ΠΏΡΠ΅ΠΏΡΡΡΡΠ²ΡΡΡΠΈΠ΅ Π΅Π³ΠΎ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΡ
Ferroelectric nanocomposites based on polymer ferroelectrics and graphene/oxide graphene: Computer modeling and SPFM experiments
The authors are thankful to the Russian Science Foundation (RSF grant # 16-19-10112) and to the Russian Foundation for Basic Researches (RFBR grants # 16-51-53917) for support. Prof. Xiang-Jian Meng expresses his gratitude to the National Natural Science Foundation of China (NNSFC) for support of the project: "The study on the new type of infrared detector based on ferroelectric tunnel junction"
Piezoelectric, ferroelectric, optoelectronic and photo-catalytic phenomena from defect levels in hydroxyapatite by first-principles
The authors thank the Russian Foundation for Basic Researches (RFBR grant 19-01-00519 A) and to the Fundação para a CiΓͺncia e a Tecnologia (FCT) through project UID/CTM/50025/2013
Peculiarities of immunological manifestations in patients with rheumatoid arthritis in the presence of chronic infection with <i>Helicobacter pylori</i> variant encoding cytotoxin-associated gene A
The study aimed to evaluate the association between cyclic citrullinated peptide antibody seropositivity and chronic Helicobacter pylori (H. pylori) infection in patients with rheumatoid arthritis (RA). We examined 92 women with moderate RA activity. Serum antibodies to cyclic citrullinated peptide (antiCCP), antibodies to H. pylori (anti-H. pylori-IgG), and total antibodies to H. pylori CagA antigen (antiCagA) were determined by enzyme immunoassay; the presence of anti-CagA-IgG positivity was confirmed by immunoblot. 68.5% of RA patients were positive for anti-H. pylori-IgG, and 44.4% of patients in this group were positive for anti-CagA-IgG. All the study participants were divided into three groups: I β H. pylori seronegative (H. pylori- ); II β H. pylori positive, CagA negative (H. pylori+/CagA- ); III β H. pylori positive and CagA positive (CagA+). The anti-CCP values in RA patients with CagA+ (group III) were significantly higher not only in comparison with patients seronegative for H. pylori (p < 0.001), but also in comparison with patients from group II (H. pylori+/CagA- ) (p = 0.041). A study of the influence of the RA activity, the presence of RF and H. pylori on anti-CCP content demonstrated a small proportion of anti-CCP variability (R2 = 0.09), with a high contribution of H. pylori (beta = 0.25). The addition of the CagA(+) index (beta = 0.503) to the presented model allowed us to describe the variability of anti-CCP in almost 30% of cases (R2 = 0.29). In the group of RA patients with anti-CCP values exceeding the established threshold value of 20 U/mL (normal index), there was an increase in the proportion of patients infected with H. pylori (p < 0.001), but not the proportion of CagA-positive patients (p = 0.06). When the threshold level was increased to 60 U/mL (three times the upper limit of normal) in patients with significantly high anti-CCP, the association with positivity for CagA became significant (p = 0.005). CagA is highly immunogenic and is capable of inducing an inflammatory response in the host that goes beyond the effect of H. pylori itself. Additional experimental studies are needed to investigate possible clinical and laboratory associations that may influence the treatment tactics of CagA+ patients with RA who are seropositive for anti-citrullinated antibodies, as well as to evaluate the possible effects of therapeutic intervention aimed at the eradication of H. pylori in this group
The balance of elements in the system βLuvic Chernozems β agricultural plantsβ on the Plavsk upland (Tula region of Russia)
To assess the transfer of macro (K, P, S, Mg, Ca, as well as Si, Na, Fe, Al, Mn and Ti) and microelements (Zn, Ba, Cu, Sr, Mo, as well as As, Zr, Pb, Co, Ni, V and Cr) from Luvic Chernozems (Aric, Loamic, Pachic) into agricultural plants, we studied the inventories of chemical elements in three agrocenoses (wheat, soybean, Galega orientalis Lam. and Bromopsis inermis Leyss grass mixtures) from the Plavsk upland (Tula Region). This territory is subjected to intensive industrial and agricultural impacts: it is 40 km away from the town of Shchekino with a nitrogen fertilizer plant and a thermal power plant, 60 km away from Tula with large metallurgical enterprises, 70 km away from the town of Novomoskovsk with several chemical enterprises and state district power plant. In soils, the total content of elements was determined by the X-ray fluorescence spectrometry. The elemental composition of plants after autoclave decomposition with a mixture of concentrated nitric acid and hydrogen peroxide and the content of the bioavailable fraction (extracted by an ammonium acetate buffer with pH 4.8) of elements in soil were estimated by the atomic emission spectrometry with inductively coupled plasma. In topsoil (a 10-cm layer), maximal inventories are typical for total Si (40 Β± 4 kg/m2), Al (7.0 Β± 0.8 kg/m2) and Fe (3.4 Β± 0.3 kg/m2) and for bioavailable Ca (570 Β± 48 g/m2), Mg (43 Β± 4 g/m2), K (22 Β± 6 g/m2). In plants, the main inventories (g/m2) of K, P, S, Mg, Si, Mn, Zn, Ba, Cu, Mo occur in the above ground phytomass. The most effectively plants assimilate bioavailable fractions of K, P, Ti, Mo, As, Zr, V. Based on the resource method for soil quality assessment, the studied Chernozems are characterized by a low level of Ni contamination, a moderate supply of bioavailable K with a lack of bioavailable P
ΠΠΠΠΠΠ ΠΠΠΠΠΠΠΠΠ― Π ΠΠΠΠΠΠΠΠΠ‘Π’Π ΠΠΠΠ€Π ΠΠΠΠ« Π£ ΠΠΠ ΠΠ‘ΠΠ«Π₯ Π‘ ΠΠΠ ΠΠΠΠ¬ΠΠΠ Π€Π£ΠΠΠ¦ΠΠΠ ΠΠΠΠΠΠ₯ ΠΠ Π ΠΠΠ‘ΠΠ ΠΠΠ ΠΠΠΠ₯ΠΠ Π£Π ΠΠΠ§ΠΠ‘ΠΠΠ₯ ΠΠΠΠ ΠΠ¦ΠΠ
A statisticalΒ analysis of position and mobility of the diaphragmΒ in adults with normal lung function is not operated and underwent various cardiac interventions. The study included 2441 the patient,Β divided into groups non-operated and undergoingΒ various cardiac surgical intervention.Β Were determinedΒ the mean values of the position and mobility of the diaphragm,Β the frequency of elevation and diaphragm dysfunction. Using ROC analysis establishedΒ the degree of influence for the elevation and dysfunction of the diaphragm of the body mass index (BMI), the coefficient of mobility of the diaphragmΒ (CMD)Β and indicatorsΒ of the position of the domes of the diaphragm.Β It is revealed that after cardiac operationsΒ the position of the domes of the diaphragm was higher and decreasedΒ mobility of the diaphragm. Elevation and dysfunction among non-operated diaphragm was noted in a few cases, and after cardiac surgery significantly more often. Non-operated patientsΒ have a statisticallyΒ significant impact on elevation of the right dome had a value of (AUC 0,99) and the elevation of the left dome of the diaphragm the magnitudeΒ of BMI (AUC of 0,89). They have not identified effects on diaphragmaticΒ dysfunction none of the studied factors. In postoperativeΒ patients, the rates of mobility of the diaphragm showed a good effect on the elevation (AUC of 0,84β0,86), while the value of BMI showed an average quality of effects in all models (AUC of 0,62 to 0,65). A statistically significant effect on diaphragm matic dysfunction provided only the position of the domes of the diaphragm (AUC 0,78β0,83). Patients undergoing different cardiac surgical intervention have a statistically significant decrease of mobility and increase the position of the diaphragm,Β increasing the frequency of elevation and dysfunction. From non-operated patientsΒ on the mobility of the diaphragm did not affect any height standingΒ domes of the diaphragm or BMI. On the position of the right dome affects only the rate of mobility of the diaphragm, and the left dome β the value of BMI. Patients after various cardiac surgeriesΒ greaterΒ impact on the elevation of the diaphragm provided an indicator of its mobility, than BMI and dysfunction of the diaphragm affects only its position.ΠΡΠΎΠ²Π΅Π΄Π΅Π½ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΈ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΠΈ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ Ρ Π²Π·ΡΠΎΡΠ»ΡΡ
Ρ Π½ΠΎΡΠΌΠ°Π»ΡΠ½ΠΎΠΉ ΡΡΠ½ΠΊΡΠΈΠ΅ΠΉ Π»Π΅Π³ΠΊΠΈΡ
, Π³ΠΎΡΠΎΠ²ΡΡΠΈΡ
ΡΡ ΠΊ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΡΠΌ ΠΈ ΠΏΠΎΡΠ»Π΅ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΠΊΠ°ΡΠ΄ΠΈΠΎΡ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ². Π ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΠΊΠ»ΡΡΠ΅Π½ 2441 ΠΏΠ°ΡΠΈΠ΅Π½Ρ, Π²ΡΠ΄Π΅Π»Π΅Π½Ρ Π³ΡΡΠΏΠΏΡ Π½Π΅ΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΈ ΠΏΠ΅ΡΠ΅Π½Π΅ΡΡΠΈΡ
ΡΠ°Π·Π»ΠΈΡΠ½ΡΠ΅ ΠΊΠ°ΡΠ΄ΠΈΠΎΡ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ²Π°. ΠΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈΒ ΡΡΠ΅Π΄Π½ΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈΒ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΈ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΠΈ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ, ΡΠ°ΡΡΠΎΡΡ ΡΠ»Π΅Π²Π°ΡΠΈΠΈ ΠΈ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠΈ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ. Π‘ ΠΏΠΎΠΌΠΎΡΡΡ ROC-Π°Π½Π°Π»ΠΈΠ·Π° ΡΡΡΠ°Π½Π°Π²Π»ΠΈΠ²Π°Π»ΠΈΒ ΡΡΠ΅ΠΏΠ΅Π½Ρ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²Π»ΠΈΡΠ½ΠΈΡ Π½Π° ΡΠ»Π΅Π²Π°ΡΠΈΡΒ ΠΈ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ ΠΈΠ½Π΄Π΅ΠΊΡΠ° ΠΌΠ°ΡΡΡ ΡΠ΅Π»Π° (ΠΠΠ’), ΠΊΠΎΡΡΡΠΈΡΠΈΠ΅Π½ΡΠ° ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΠΈ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ (ΠΠΠ) ΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ ΠΊΡΠΏΠΎΠ»ΠΎΠ² Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ. ΠΡΡΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΠΏΠΎΡΠ»Π΅ ΠΊΠ°ΡΠ΄ΠΈΠΎΡ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΉ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ ΠΊΡΠΏΠΎΠ»ΠΎΠ² Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ Π±ΡΠ»ΠΎ Π²ΡΡΠ΅, ΡΠ½ΠΈΠΆΠ°Π»Π°ΡΡ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΡ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ. ΠΠ»Π΅Π²Π°ΡΠΈΡ ΠΈ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ ΡΡΠ΅Π΄ΠΈ Π½Π΅ΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΎΡΠΌΠ΅ΡΠ°Π»ΠΈΡΡ Π² Π΅Π΄ΠΈΠ½ΠΈΡΠ½ΡΡ
ΡΠ»ΡΡΠ°ΡΡ
, Π° ΠΏΠΎΡΠ»Π΅ ΠΊΠ°ΡΠ΄ΠΈΠΎΡ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΉ Π² ΡΠ°Π·Ρ ΡΠ°ΡΠ΅. Π£ Π½Π΅ΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΠΎΠ΅ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° ΡΠ»Π΅Π²Π°ΡΠΈΡ ΠΏΡΠ°Π²ΠΎΠ³ΠΎ ΠΊΡΠΏΠΎΠ»Π° ΠΎΠΊΠ°Π·ΡΠ²Π°Π» Π»ΠΈΡΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Ρ ΠΠΠ (AUC 0,99), Π° Π½Π° ΡΠ»Π΅Π²Π°ΡΠΈΡ Π»Π΅Π²ΠΎΠ³ΠΎ ΠΊΡΠΏΠΎΠ»Π° Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ β Π²Π΅Π»ΠΈΡΠΈΠ½Π° ΠΠΠ’ (AUC 0,89). Π£ Π½ΠΈΡ
Π½Π΅ Π²ΡΡΠ²Π»Π΅Π½ΠΎΒ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎΒ Π²Π»ΠΈΡΠ½ΠΈΡΒ Π½Π°Β Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΠ°Π»ΡΠ½ΡΡΒ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ Π½ΠΈΒ ΠΎΠ΄Π½ΠΎΠ³ΠΎ ΠΈΠ·Β ΠΈΠ·ΡΡΠ°Π΅ΠΌΡΡ
Β ΡΠ°ΠΊΡΠΎΡΠΎΠ². Π£ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΠΈ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ Ρ
ΠΎΡΠΎΡΠΈΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²Π»ΠΈΡΠ½ΠΈΡ Π½Π° ΡΠ»Π΅Π²Π°ΡΠΈΡΒ (AUC 0,84β0,86), Π² ΡΠΎ Π²ΡΠ΅ΠΌΡΒ ΠΊΠ°ΠΊ Π²Π΅Π»ΠΈΡΠΈΠ½Π° ΠΠΠ’Β ΠΏΠΎΠΊΠ°Π·Π°Π»Π°Β ΡΡΠ΅Π΄Π½Π΅Π΅ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ Π²Π»ΠΈΡΠ½ΠΈΡ Π²ΠΎ Π²ΡΠ΅Ρ
ΠΌΠΎΠ΄Π΅Π»ΡΡ
(AUC 0,62β0,65). Π‘ΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΠΎΠ΅ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΠ°Π»ΡΠ½ΡΡ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ ΠΎΠΊΠ°Π·ΡΠ²Π°Π»ΠΎ ΡΠΎΠ»ΡΠΊΠΎ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠ΅ ΠΊΡΠΏΠΎΠ»ΠΎΠ² Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ (AUC 0,78β0,83). Π£ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΡΠΌΠ΅Π½ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΠΈ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ ΠΌΠ΅Π½Π΅Π΅ 8β8,9 Ρ. Π΅. Ρ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡΡ ΠΈ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΡΡ ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π»ΠΎ Π΅Π΅ ΡΠ»Π΅Π²Π°ΡΠΈΡ. Π£Π²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ ΠΠΠ’ Π±ΠΎΠ»Π΅Π΅ 28β28,6 ΠΊΠ³/ΠΌ2Β ΠΈΠΌΠ΅Π»ΠΎ ΡΡΠ΅Π΄Π½Π΅Π΅ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° ΡΠ»Π΅Π²Π°ΡΠΈΡ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ, ΠΏΡΠΈ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΈ ΠΌΠ°Π»ΠΎΠΉ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ. ΠΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡΒ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΡ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ ΠΌΠΎΠΆΠ½ΠΎ ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·Π°ΡΡΒ ΡΠΎΠ»ΡΠΊΠΎ ΠΏΠΎ Π΅Π΅ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΡ: Ρ
ΠΎΡΠΎΡΠΈΠΉ Π±Π°Π»Π°Π½Ρ ΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΈ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΡΡΠΈ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π° ΠΎΡΠΌΠ΅ΡΠ°Π»ΡΡ ΠΏΡΠΈ ΠΏΠΎΠ΄ΡΠ΅ΠΌΠ΅ ΠΊΡΠΏΠΎΠ»ΠΎΠ² Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ Π²ΡΡΠ΅ ΠΌΠ΅ΠΆΠΏΠΎΠ·Π²ΠΎΠ½ΠΊΠΎΠ²ΠΎΠ³ΠΎ Π΄ΠΈΡΠΊΠ° VIIβIX Π³ΡΡΠ΄Π½ΡΡ
ΠΏΠΎΠ·Π²ΠΎΠ½ΠΊΠΎΠ². Π£ Π½Π΅ΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π½Π° ΠΏΠΎΠ΄Π²ΠΈΠΆΠ½ΠΎΡΡΡ Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ Π½Π΅ Π²Π»ΠΈΡΠ»ΠΈ Π½ΠΈ Π²ΡΡΠΎΡΠ° ΡΡΠΎΡΠ½ΠΈΡ ΠΊΡΠΏΠΎΠ»ΠΎΠ² Π΄ΠΈΠ°ΡΡΠ°Π³ΠΌΡ, Π½ΠΈ ΠΠΠ’
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