7,276 research outputs found

    Investigation of the phenomenon of the big comet of 1858

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    Various aspects of the large comet of 1858 including the luminosity of the core and the shape, intensity and position of the tail with respect to the sun and stars are described and then compared with the large comet of 1744 described by Heinsius and Halley's comet of 1835. The purpose of these observations is to try to gain a clearer understanding of the nature of the polar force from the sun acting on the comet. This force is said to differ from the usual force of gravity

    Multilayered printed circuit boards inspected by X-ray laminography

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    Technique produces high resolution cross-sectional radiographs with close interplane spacing for inspecting multilayer boards to be used in providing circuitry routing and module structural support

    A clone-free, single molecule map of the domestic cow (Bos taurus) genome.

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    BackgroundThe cattle (Bos taurus) genome was originally selected for sequencing due to its economic importance and unique biology as a model organism for understanding other ruminants, or mammals. Currently, there are two cattle genome sequence assemblies (UMD3.1 and Btau4.6) from groups using dissimilar assembly algorithms, which were complemented by genetic and physical map resources. However, past comparisons between these assemblies revealed substantial differences. Consequently, such discordances have engendered ambiguities when using reference sequence data, impacting genomic studies in cattle and motivating construction of a new optical map resource--BtOM1.0--to guide comparisons and improvements to the current sequence builds. Accordingly, our comprehensive comparisons of BtOM1.0 against the UMD3.1 and Btau4.6 sequence builds tabulate large-to-immediate scale discordances requiring mediation.ResultsThe optical map, BtOM1.0, spanning the B. taurus genome (Hereford breed, L1 Dominette 01449) was assembled from an optical map dataset consisting of 2,973,315 (439 X; raw dataset size before assembly) single molecule optical maps (Rmaps; 1 Rmap = 1 restriction mapped DNA molecule) generated by the Optical Mapping System. The BamHI map spans 2,575.30 Mb and comprises 78 optical contigs assembled by a combination of iterative (using the reference sequence: UMD3.1) and de novo assembly techniques. BtOM1.0 is a high-resolution physical map featuring an average restriction fragment size of 8.91 Kb. Comparisons of BtOM1.0 vs. UMD3.1, or Btau4.6, revealed that Btau4.6 presented far more discordances (7,463) vs. UMD3.1 (4,754). Overall, we found that Btau4.6 presented almost double the number of discordances than UMD3.1 across most of the 6 categories of sequence vs. map discrepancies, which are: COMPLEX (misassembly), DELs (extraneous sequences), INSs (missing sequences), ITs (Inverted/Translocated sequences), ECs (extra restriction cuts) and MCs (missing restriction cuts).ConclusionAlignments of UMD3.1 and Btau4.6 to BtOM1.0 reveal discordances commensurate with previous reports, and affirm the NCBI's current designation of UMD3.1 sequence assembly as the "reference assembly" and the Btau4.6 as the "alternate assembly." The cattle genome optical map, BtOM1.0, when used as a comprehensive and largely independent guide, will greatly assist improvements to existing sequence builds, and later serve as an accurate physical scaffold for studies concerning the comparative genomics of cattle breeds

    On the Elastohydrodynamic Film-Forming Properties of Metalworking Fluids and Oil-in-Water Emulsions

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    Oil-in-water (O/W) emulsions are water-based lubricants and used as fire-resistant hydraulic fluids and metalworking fluids (MWFs) in industry. The (elasto-)hydrodynamic film-forming properties of O/W emulsions have been studied extensively in literature. Typical elastohydrodynamic lubrication (EHL) behaviors are revealed at low rolling speeds followed by a starved EHL regime at elevated speeds. These emulsions are self-prepared and mostly stable only for a limited time ranging from hours to several days. By contrast, the film-forming behavior of water-miscible commercial MWFs (long-term stable O/W emulsions) has rarely been reported. This restricts the understanding of the lubrication status of many tribological interfaces in manufacturing processes, e.g., the chip-tool contact in cutting. In this work, the (elasto-)hydrodynamic film-forming property of two commercial MWFs is investigated by measuring the film thickness on two ball-on-disc test rigs using different optical interferometry techniques. For comparison, two self-prepared simple O/W emulsions with known formulation have also been investigated. Experimental results from the two test rigs agree well and show that the two self-prepared emulsions have typical EHL behaviors as reported in literature. However, for the two commercial MWFs, there is almost no (elasto-)hydrodynamic film-forming ability over the whole range of speeds used in this study. This could be explained by the cleaning and re-emulsification effects of the MWFs. The lubrication mechanism of the two MWFs is mainly boundary lubrication rather than hydrodynamic lubrication. Graphical Abstract: [Figure not available: see fulltext.]

    BNCI systems as a potential assistive technology: ethical issues and participatory research in the BrainAble project

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    This paper highlights aspects related to current research and thinking about ethical issues in relation to Brain Computer Interface (BCI) and Brain-Neuronal Computer Interfaces (BNCI) research through the experience of one particular project, BrainAble, which is exploring and developing the potential of these technologies to enable people with complex disabilities to control computers. It describes how ethical practice has been developed both within the multidisciplinary research team and with participants. Results: The paper presents findings in which participants shared their views of the project prototypes, of the potential of BCI/BNCI systems as an assistive technology, and of their other possible applications. This draws attention to the importance of ethical practice in projects where high expectations of technologies, and representations of “ideal types” of disabled users may reinforce stereotypes or drown out participant “voices”. Conclusions: Ethical frameworks for research and development in emergent areas such as BCI/BNCI systems should be based on broad notions of a “duty of care” while being sufficiently flexible that researchers can adapt project procedures according to participant needs. They need to be frequently revisited, not only in the light of experience, but also to ensure they reflect new research findings and ever more complex and powerful technologies

    Neutron time-of-flight measurements of charged-particle energy loss in inertial confinement fusion plasmas

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    Neutron spectra from secondary ^{3}H(d,n)α reactions produced by an implosion of a deuterium-gas capsule at the National Ignition Facility have been measured with order-of-magnitude improvements in statistics and resolution over past experiments. These new data and their sensitivity to the energy loss of fast tritons emitted from thermal ^{2}H(d,p)^{3}H reactions enable the first statistically significant investigation of charged-particle stopping via the emitted neutron spectrum. Radiation-hydrodynamic simulations, constrained to match a number of observables from the implosion, were used to predict the neutron spectra while employing two different energy loss models. This analysis represents the first test of stopping models under inertial confinement fusion conditions, covering plasma temperatures of k_{B}T≈1-4  keV and particle densities of n≈(12-2)×10^{24}  cm^{-3}. Under these conditions, we find significant deviations of our data from a theory employing classical collisions whereas the theory including quantum diffraction agrees with our data

    Does a dissolution-precipitation mechanism explain concrete creep in moist environments?

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    Long-term creep (i.e., deformation under sustained load) is a significant material response that needs to be accounted for in concrete structural design. However, the nature and origin of creep remains poorly understood, and controversial. Here, we propose that concrete creep at RH (relative humidity) > 50%, but fixed moisture-contents (i.e., basic creep), arises from a dissolution-precipitation mechanism, active at nanoscale grain contacts, as is often observed in a geological context, e.g., when rocks are exposed to sustained loads, in moist environments. Based on micro-indentation and vertical scanning interferometry experiments, and molecular dynamics simulations carried out on calcium-silicate-hydrates (C-S-H's), the major binding phase in concrete, of different compositions, we show that creep rates are well correlated to dissolution rates - an observation which supports the dissolution-precipitation mechanism as the origin of concrete creep. C-S-H compositions featuring high resistance to dissolution, and hence creep are identified - analysis of which, using topological constraint theory, indicates that these compositions present limited relaxation modes on account of their optimally connected (i.e., constrained) atomic networks
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