Role of Inflammation in the Pathogenesis of Diabetic Nephropathy

Diabetic nephropathy is the major microvascular complication of diabetes mellitus and remains the leading cause of increased morbidity and mortality for diabetic patients. Recent evidence suggests that chronic subclinical inflammation is a key pathogenetic mechanism of the disease. Pro-inflammatory cytokines and particularly tumor necrosis factor and its receptors appear to play a major role in the process and are emerging novel biomarkers of the development and progression of diabetic nephopathy. Moreover, manipulation of the TNF superfamily system will hopefully provide a new therapeutic option for the disease

Women Filmmakers in the United Arab Emirates

This entry provides an introduction to the work of and the challenges faced by women filmmakers in the United Arab Emirates while at the same time providing an overview of the emerging film industry in the country. The fact that these women claim the power of representation and start telling their stories against the backdrop of a conservative, patriarchal society, obviously opens up space for gender redefinition. Overall, it seems that their films reveal a preference for strong, interesting women that fight for a meaningful life against the backdrop of a globalized society that has left women weaker and more fragile, with less obvious choices and possibilities for fulfillment. As their female characters claim center stage, both traditional and contemporary constructions of gender are called into question and popular stereotypes about Emirati women are challenged

Slice Isolation for 5G Transport Networks

Network slicing plays a key role in the 5G ecosystem for vertical industries to introduce new services. However, one widely-recognized challenge of network slicing is to provide traffic isolation and concurrently satisfy diverse performance requirements, e.g., bandwidth and latency. In this work, we showcase the capability to retain these two goals at the same time, via extending the 5Growth baseline architecture and designing a new data-plane pipeline, i.e., virtual queue, over the P4 switch. To demonstrate the effectiveness of our approach, a proof-of-concept is presented serving different service requests over a mixed data path, including P4 switches and Open vSwitches (OvSs)

牛糞堆肥を施用した畑地における大腸菌の流出抑制に関する研究

2013東京農業大

Case Report Calciphylaxis: Temporal Artery Calcification Preceding Widespread Skin Lesions and Penile Necrosis

Temporal artery calciphylaxis has rarely been described in chronic kidney disease patients on dialysis. We report a case of 72-year-old Caucasian man with multiple comorbidities and end-stage renal disease on dialysis who presented with temporal artery calcification leading to bilateral loss of vision followed by extensive skin lesions including one on glans penis. While on peritoneal dialysis, he developed anterior ischemic optic neuropathy, had no improvement on high dose steroids, and temporal artery biopsy showed marked calcification without any evidence of vasculitis. Few weeks later on hemodialysis, he developed widespread cutaneous lesions on extremities and penile necrosis with skin biopsy revealing calciphylaxis. On literature review of calciphylaxis in chronic kidney disease, we found only four cases of temporal artery calciphylaxis leading to anterior ischemic optic neuropathy and blindness. We believe this is the first case in which the rare temporal artery calciphylaxis and the uncommon penile necrosis are being described together. The objective is to emphasize the need to recognize this condition early in the CKD patients on dialysis presenting with visual symptoms as the different treatment strategies may help prevent complete loss of vision and also modify or prevent a full blown calciphylaxis