The Evaluation of Common Bean (Phaseolus vulgaris L.) Genotypes under Water Stress Based on Physiological and Agronomic Parameters

Drought affects common bean productivity, and the severity of its impact is expected to increase due to climate change. The use of versatile genotypes could contribute to securing future bean production. This study investigates the adaptability of 10 common bean genotypes of indeterminate growth type under water scarcity conditions by measuring agronomic and physiological parameters. The evaluation occurs under irrigation treatments applied at two different phenological stages (anthesis (WDA) and seed filling initiation (WDSF)). The recorded adaptabilities of the genotypes (G) showed that G10 produced the highest overall seed yield in the normal irrigation (NI) (197.22 g plant−1) and WDA (192.78 g plant−1), while the G6 had the highest yield at WDSF (196.71 g plant−1). For the genotype’s average mean, chlorophyll content decreased by 10.5% under drought at WDSF. Net photosynthetic rate (Pn), stomatal conductance (gs), and transpiration rate (E) were reduced at WDA by 53%, 80.8%, and 61.4% and at WDSF by 43.75%, 57.7%, and 36%, respectively, while relative water content (RWC) reduced by 16.48%, on average, for both stages. G10 and G6 showed adaptability when water scarcity occurred at an early (WDA) or later stage (WDSF), respectively, providing insights into using germplasm resources to cope with the drought effect. © 2022 by the authors

Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients

Background: Amyotrophic lateral sclerosis (ALS) is a devastating disease whose complex pathology has been associated with a strong genetic component in the context of both familial and sporadic disease. Herein, we adopted a next-generation sequencing approach to Greek patients suffering from sporadic ALS (together with their healthy counterparts) in order to explore further the genetic basis of sporadic ALS (sALS). Results: Whole-genome sequencing analysis of Greek sALS patients revealed a positive association between FTO and TBC1D1 gene variants and sALS. Further, linkage disequilibrium analyses were suggestive of a specific diseaseassociated haplotype for FTO gene variants. Genotyping for these variants was performed in Greek, Sardinian, and Turkish sALS patients. A lack of association between FTO and TBC1D1 variants and sALS in patients of Sardinian and Turkish descent may suggest a founder effect in the Greek population. FTO was found to be highly expressed in motor neurons, while in silico analyses predicted an impact on FTO and TBC1D1 mRNA splicing for the genomic variants in question. Conclusions: To our knowledge, this is the first study to present a possible association between FTO gene variants and the genetic etiology of sALS. In addition, the next-generation sequencing-based genomics approach coupled with the two-step validation strategy described herein has the potential to be applied to other types of human complex genetic disorders in order to identify variants of clinical significance. © The Author(s)

Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients

Background: Amyotrophic lateral sclerosis (ALS) is a devastating disease whose complex pathology has been associated with a strong genetic component in the context of both familial and sporadic disease. Herein, we adopted a next-generation sequencing approach to Greek patients suffering from sporadic ALS (together with their healthy counterparts) in order to explore further the genetic basis of sporadic ALS (sALS). Results: Whole-genome sequencing analysis of Greek sALS patients revealed a positive association between FTO and TBC1D1 gene variants and sALS. Further, linkage disequilibrium analyses were suggestive of a specific diseaseassociated haplotype for FTO gene variants. Genotyping for these variants was performed in Greek, Sardinian, and Turkish sALS patients. A lack of association between FTO and TBC1D1 variants and sALS in patients of Sardinian and Turkish descent may suggest a founder effect in the Greek population. FTO was found to be highly expressed in motor neurons, while in silico analyses predicted an impact on FTO and TBC1D1 mRNA splicing for the genomic variants in question. Conclusions: To our knowledge, this is the first study to present a possible association between FTO gene variants and the genetic etiology of sALS. In addition, the next-generation sequencing-based genomics approach coupled with the two-step validation strategy described herein has the potential to be applied to other types of human complex genetic disorders in order to identify variants of clinical significance. © The Author(s)

Charged particle multiplicity distributions in Z0 hadronic decays

This paper presents an analysis of the multiplicity distributions of charged particles produced in Z0 hadronic decays in the DELPHI detector. It is based on a sample of 25364 events. The average multiplicity is <nch>=20.71±0.04(stat)±0.77(syst) and the dispersion D=6.28±0.03(stat)±0.43(syst). The data are compared with the results at lower energies and with the predictions of phenomenological models. The Lund parton shower model describes the data reasonably well. The multiplicity distributions show approximate KNO-scaling. They also show positive forward-backward correlations that are strongest in the central region of rapidity and for particles of opposite charge. © 1991 Springer-Verlag

Search for scalar quarks in Z0 decays

A search has been made for pairs of scalar quarks (squarks) produced in e+e- annihilations at LEP (√s≃MZ0), and decaying into a standard quark and a neutral, non-interacting, stable, massive particle (the lightest supersymmetric particle, LSP). The search has been conducted for differences in the mass of the squark and LSP of 2 GeV/c2 and above. Up squarks with masses below 42 GeV/c2 and down squarks below 43 GeV/c2 were excluded. Six squark flavours degenerate in mass were excluded below 45 GeV/c2.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe

SEARCH FOR THE t AND b-prime QUARKS IN HADRONIC DECAYS OF THE Z0 BOSON

We present a search for the third generation up type quark t and a possible fourth down type quark b' in hadronic Z0 decays observed in DELPHI at the LEP collider. For any scenario with a decay through the charged current or into a charged Higgs with a mass at least 6 GeV/c2 below the t and 3 GeVc2 below the b' mass, we set a lower limit for the t quark mass at 44.0 GeV/c2 and for the b' mass at 44.5 GeV/c2. For specific scenarios the mass limits are slightly higher, e.g. for charged current decays the limits are 44.5 and 45.0 GeV/c2 respectively, where all limits are given at a 95% confidence level. © 1990.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe

A Search for sleptons and gauginos in Z0 decays

Using a data sample corresponding to 10 000 hadronic Z0 decays, we have searched for the production of sleptons and gauginos in the two-prong decays of Z0. No candidate remains after straightforward selections. For neutralinos, we use selection methods developed in our previous search for neutral Higgs particles. The negative results are translated into improved mass limits and parameter constraints on the minimal supersymmetric extension of the standard model

A Comparison of jet production rates on the Z0 resonance to perturbative QCD

The production rates for 2-, 3-, 4- and 5-jet hadronic final states have been measured with the DELPHI detector at the e+e- storage ring LEP at centre of mass energies around 91.5 GeV. Fully corrected data are compared to O(αs 2) QCD matrix element calculations and the QCD scale parameter ΛMS is determined for different parametrizations of the renormalization scale μ2. Including all uncertainties our result is αs(MZ 2)=0.114±0.003[stat.]±0.004[syst.]±0.012[theor.] .0SCOPUS: ar.jinfo:eu-repo/semantics/publishe