8,696 research outputs found

    Approaches to Semantic Web Services: An Overview and Comparison

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    Abstract. The next Web generation promises to deliver Semantic Web Services (SWS); services that are self-described and amenable to automated discovery, composition and invocation. A prerequisite to this, however, is the emergence and evolution of the Semantic Web, which provides the infrastructure for the semantic interoperability of Web Services. Web Services will be augmented with rich formal descriptions of their capabilities, such that they can be utilized by applications or other services without human assistance or highly constrained agreements on interfaces or protocols. Thus, Semantic Web Services have the potential to change the way knowledge and business services are consumed and provided on the Web. In this paper, we survey the state of the art of current enabling technologies for Semantic Web Services. In addition, we characterize the infrastructure of Semantic Web Services along three orthogonal dimensions: activities, architecture and service ontology. Further, we examine and contrast three current approaches to SWS according to the proposed dimensions

    Causality in collective filtering

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    In this paper, we describe a proposal for improving the practice of web-based collective filtering, in particular for what regards discussions and selection of issues about policy, based on the intuitive concept of causality. Causality, especially when presented in visual form, is especially suited to the task since it is intuitive to understand and to use, and at the same time, it's rich enough to create a semantic network between the representations of real world facts. We give some examples of the suggested system workflow and we present guidelines for its implementation

    Simulations of working memory spiking networks driven by short-term plasticity

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    Working Memory (WM) is a cognitive mechanism that enables temporary holding and manipulation of information in the human brain. This mechanism is mainly characterized by a neuronal activity during which neuron populations are able to maintain an enhanced spiking activity after being triggered by a short external cue. In this study, we implement, using the NEST simulator, a spiking neural network model in which the WM activity is sustained by a mechanism of short-term synaptic facilitation related to presynaptic calcium kinetics. The model, which is characterized by leaky integrate-and-fire neurons with exponential postsynaptic currents, is able to autonomously show an activity regime in which the memory information can be stored in a synaptic form as a result of synaptic facilitation, with spiking activity functional to facilitation maintenance. The network is able to simultaneously keep multiple memories by showing an alternated synchronous activity which preserves the synaptic facilitation within the neuron populations holding memory information. The results shown in this study confirm that a WM mechanism can be sustained by synaptic facilitation

    Integrazioni alla flora vascolare dell’Italia centrale.

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    Additions to the vascular flora of the Central Italy. In this work new floristic records for 46 units are reported for some regions of Central Italy. Particularly 25 are new or confirmed to Abruzzo, 1 is new to Marche and 1 to Molise. In addition new distribution data for 18 units rare or interesting in Abruzzo and 1 in Molise regions have been recorded. The survey was carried out from 2010 to 2015 through field research, revision of herbarium specimens and literature studies. Some recorded species are particularly interesting from a phytogeo¬graphical or conservational point of view as they are very rare in Cen¬tral Italy. The results also show a high presence of new alien species

    Immunotherapy with low-dose recombinant interleukin 2 after high-dose chemotherapy and autologous stem cell transplantation in neuroblastoma.

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    The purpose of this study was to evaluate in a phase I-II trial whether low doses of recombinant human interleukin 2 (rHuIL-2) over a prolonged period of time are safe and effective in eradicating or controlling minimal residual disease in children with neuroblastoma given high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT). From January 1992 to July 1996, 17 consecutive patients, with either stage IV or relapsed neuroblastoma, were enrolled. Patients received rHuIL-2 after a median time interval (min-max) of 105 days (56-153) after HDCT and ASCT. The protocol consisted of 2 'priming' courses of rHuIL-2 at escalating doses administered intravenously at 72-h intervals, followed by 'maintenance' with 11 monthly and six bimonthly boosting 5-day courses administered subcutaneously on an outpatient basis. At April 1997, 7 out of the 17 patients had completed the treatment schedule, four had discontinued treatment because of toxicity and four because of relapse; the remaining two patients are still on treatment, having completed 15 courses. Expansion of T lymphocytes, together with an increase in both natural killer cells and in activated T lymphocytes was evidenced. After a median (min-max) follow-up time of 30 (16-64) months, 12 out of 17 patients are alive and well. Two patients relapsed and died 14 and 35 months after transplant. Three patients are alive after having relapsed at 41, 21 and 13 months. The actuarial 2-year event-free survival and overall survival are 67% and 92% respectively. Intermittent administration of low doses of rHuIL-2 given for a long period of time is well tolerated and seems capable of controlling minimal residual disease after HDCT and ASCT in children with high-risk neuroblastoma

    Disaggregated optical network control and orchestration of heterogeneous domains

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    Network softwarization and disaggregation are two trends that are revolutionizing the network-cloud ecosystem. This paper details possible solutions to control and monitor an infrastructure including an IoT domain, a Cloud domain and a packet-optical network domain

    Development and testing of the propulsion system of MARTA AUV

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    This work deals with the design of the propulsion system of a modular AUV (Autonomous Underwater Vehicle). The authors describe the design methodologies and the testing devices used for the fast prototyping of MARTA (MARine Tool for Archaeology) AUV actuation system, including drivers, motors and propellers. In particular, the authors introduce the design criteria followed for the preliminary testing activities and the methodologies adopted for fast testing and prototyping of the proposed solutions. This is a quite important topic considering the high customization and the reliability required by this kind of applications

    Interventions for improving clinical outcomes and health-related quality-of-life for people living with skeletal dysplasias: an evidence gap map

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    Purpose: Skeletal dysplasias are rare genetic disorders that are characterized by abnormal development of bone and cartilage. There are multiple medical and non-medical treatments for specific symptoms of skeletal dysplasias e.g. pain, as well as corrective surgical procedures to improve physical functioning. The aim of this paper was to develop an evidence-gap map of treatment options for skeletal dysplasias, and their impact on patient outcomes. Methods: We conducted an evidence-gap map to identify the available evidence on the impact of treatment options on people with skeletal dysplasias on clinical outcomes (such as increase in height), and dimensions of health-related quality of life. A structured search strategy was applied to five databases. Two reviewers independently assessed articles for inclusion in two stages: titles and abstracts (stage 1), and full text of studies retained at stage 2. Results: 58 studies fulfilled our inclusion criteria. The included studies covered 12 types of skeletal dysplasia that are non-lethal with severe limb deformities that could result in significant pain and numerous orthopaedic interventions. Most studies reported on the effect of surgical interventions (n = 40, 69%), followed by the effect of treatments on dimensions of health quality-of-life (n = 4, 6.8%) and psychosocial functioning (n = 8, 13.8%). Conclusion: Most studies reported on clinical outcomes from surgery for people living with Achondroplasia. Consequently, there are gaps in the literature on the full range of treatment options (including no active treatment), outcomes and the lived experience of people living with other skeletal dysplasias. More research is warranted to examine the impact of treatments on health-related quality-of-life of people living with skeletal dysplasias, including their relatives to enable them to make preference- and valued based decisions about treatment

    Aggiunte alla flora vascolare d’Abruzzo e aree limitrofe. IV contributo

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    Additions to the vascular flora of Abruzzo and surrounding. IV contribution. In this paper new floristic records for 22 units are reported for Central Italy, mainly for Abruzzo. In particular 14 taxa are native and 8 aliens, 16 are new or confirmed to Abruzzo, 1 is new to Marche. In addition new distribution data for 4 rare or interesting in Abruzzo and 1 in Lazio regions have been recorded. Some of these species are particularly interesting from a phytogeographical or conservational point of view as they are very rare in Central Italy (Antirrhinum siculum, Convolvulus pentapetaloides and Vicia melanops)
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