5,571 research outputs found

    Bianchi type-II cosmological model: some remarks

    Full text link
    Within the framework of Bianchi type-II (BII) cosmological model the behavior of matter distribution has been considered. It is shown that the non-zero off-diagonal component of Einstein tensor implies some severe restriction on the choice of matter distribution. In particular for a locally rotationally symmetric Bianchi type-II (LRS BII) space-time it is proved that the matter distribution should be strictly isotropic if the corresponding matter field possesses only non-zero diagonal components of the energy-momentum tensor.Comment: 3 page

    Short communication: Uncovering quantitative trait loci associated with resistance to Mycobacterium avium ssp. paratuberculosis infection in Holstein cattle using a high-density single nucleotide polymorphism panel

    Get PDF
    peer-reviewedMycobacterium avium ssp. paratuberculosis (MAP) is the etiological agent of Johne's disease in cattle. Johne's disease is a disease of significant economic, animal welfare, and public health concern around the globe. Therefore, understanding the genetic architecture of resistance to MAP infection has great relevance to advance genetic selection methods to breed more resistant animals. The objectives of this study were to perform a genome-wide association study of previously analyzed 50K genotypes now imputed to a high-density single nucleotide polymorphism panel (777K), aiming to validate previously reported associations and potentially identify additional single nucleotide polymorphisms associated with antibody response to MAP infection. A principal component regression-based genome-wide association study revealed 15 putative quantitative trait loci (QTL) associated with the MAP infection phenotype (serum or milk ELISA tests) on 9 different chromosomes (Bos taurus autosomes 5, 6, 7, 10, 14, 15, 16, 20, and 21). These results validated previous findings and identified new QTL on Bos taurus autosomes 15, 16, 20, and 21. The positional candidate genes NLRP3, IFi47, TRIM41, TNFRSF18, and TNFRSF4 lying within these QTL were identified. Further functional validation of these genes is now warranted to investigate their roles in regulating the immune response and, consequently, cattle resistance to MAP infection

    A Complete Set of VSOP Observations of 3C279

    Get PDF
    We have compiled a complete set of VSOP observations of 3C279, consisting of eight 5 GHz, and six 1.6 GHz, VSOP observations, all of which include the VLBA in the ground array. We are using the data-set to determine brightness temperature limits from model-fits to the visibilities, the transverse structure of the jet over its first 20 milliarcseconds, and parsec-scale spectral index maps

    High speed plasma diagnostics for laser plasma interaction and fusion studies

    Get PDF
    Laser plasma interaction and fusion studies involve many high speed plasma diagnostics to determine the various parameters for explaining the physical processes taking place in plasma. Detection and analysis of short-term or transient radiations (X-ray and visible) are the bases for diagnosing the physical processes occurring during laser-plasma interaction or similar radiation-emitting processes. This paper reviews the development of various high speed plasma diagnostics which are not only applicable in determining the temporal, spatial and spectral properties of X-rays for this purpose but also have wide use in various other fields of research

    Development of picosecond time resolution optical and X-ray streak cameras

    Get PDF
    We describe the development of an optical and an X-ray streak camera with picosecond time resolution. The entire peripheral electronics and testing systems have been developed indigenously. Both the streak cameras provide ~ 15 mm/1 ns streak rate with a sweep voltage of ~ 1 kV amplitude and rise time of 1 ns. The time and spatial resolution of the optical streak camera have been found to be ~ 17 ps and 100 μm respectively. The sweep pulse generator developed for this purpose provides a step pulse of rise time ≤ 1 ns and amplitude ~ 2 kV. The laser diode used for testing the optical streak camera provides multiple pulsation when the pump current is increased beyond a critical threshold

    Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs

    Get PDF
    Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.Cell transformation assays (CTAs) have long been proposed as in vitro methods for the identification of potential chemical carcinogens. Despite showing good correlation with rodent bioassay data, concerns over the subjective nature of using morphological criteria for identifying transformed cells and a lack of understanding of the mechanistic basis of the assays has limited their acceptance for regulatory purposes. However, recent drivers to find alternative carcinogenicity assessment methodologies, such as the Seventh Amendment to the EU Cosmetics Directive, have fuelled renewed interest in CTAs. Research is currently ongoing to improve the objectivity of the assays, reveal the underlying molecular changes leading to transformation and explore the use of novel cell types. The UK NC3Rs held an international workshop in November 2010 to review the current state of the art in this field and provide directions for future research. This paper outlines the key points highlighted at this meeting

    North-South Distribution of Solar Flares during Cycle 23

    Full text link
    In this paper, we investigate the spatial distribution of solar flares in the northern and southern hemisphere of the Sun that occurred during the period 1996 to 2003. This period of investigation includes the ascending phase, the maximum and part of descending phase of solar cycle 23. It is revealed that the flare activity during this cycle is low compared to previous solar cycle, indicating the violation of Gnevyshev-Ohl rule. The distribution of flares with respect to heliographic latitudes shows a significant asymmetry between northern and southern hemisphere which is maximum during the minimum phase of the solar cycle. The present study indicates that the activity dominates the northern hemisphere in general during the rising phase of the cycle (1997-2000). The dominance of northern hemisphere is shifted towards the southern hemisphere after the solar maximum in 2000 and remained there in the successive years. Although the annual variations in the asymmetry time series during cycle 23 are quite different from cycle 22, they are comparable to cycle 21.Comment: 6 pages, 2 figures, 1 table; Accepted for the publication in the proceedings of international solar workshop held at ARIES, Nainital, India on "Transient Phenomena on the Sun and Interplanetary Medium" in a special issue of "Journal of Astrophysics and Astronomy (JAA)

    Meteorite falls over India during 2003: Petrographic and chemical characterization and cosmogenic records

    Get PDF
    Two meteorite falls observed over India in 2003 led to the recovery of surviving fragments. The Kasauli meteorite that fell in northern India is a single fall, while Kendrapara meteorite is a multiple fall that covered a large coastal region of Orissa. Data for petrographic characteristics and chemical composition suggest that the two meteorites belong to the H group of chondrites, with Kasuali suffering a lesser degree of thermal metamorphism than Kendrapara during their residence in their parent bodies. Cosmogenic records indicate a large size (≥1 m) for the Kendrapara meteoroid that has spent ~5 million years in interplanetary space following its ejection from its parent body until its fall on the Earth. On the other hand, the Kasauli meteoroid spent an unusually long time (~37 Ma) in interplanetary space before its fall and lost ~80% of its original mass during atmospheric ablation
    corecore