Propuesta didáctica para el desarrollo de las competencias del área de comunicación de cuarto grado de primaria de una Institución Educativa Privada de Punta Negra, Lima

El presente trabajo de suficiencia profesional que a continuación se presenta, tiene como objetivo diseñar una propuesta didáctica para el desarrollo de competencias comunicativas en los estudiantes de cuarto grado de primaria de una institución educativa privada de Lima. Para ello, se basa en el Paradigma Sociocognitivo Humanista de: Jean Piaget, David Ausubel y Jerome Bruner (cognitivo), Lev Vygotsky y Reaven Feuerstein (social y cultural), Robert Sternberg, Martiniano Román y Eloísa Diez (Teoría de la Inteligencia). A través de esta propuesta, el estudiante se vincula con competencias, capacidades y destrezas; donde no solo adquiere conocimientos, sino también aprende valores para que pueda socializar con sus conocimientos en esta sociedad cambiante. Así, esta propuesta contiene en el primer capítulo la planificación del trabajo de suficiencia profesional; el segundo, marco teórico y como último capítulo la programación curricular.The present work of professional sufficiency that is presented below, aims to design a didactic proposal for the development of communication skills in fourth grade students of a private educational institution in Lima. For this, it is based on the Humanistic Sociocognitive Paradigm of: Jean Piaget, David Ausubel and Jerome Bruner (cognitive), Lev Vygotsky and Reaven Feuerstein (social and cultural), Robert Sternberg, Martiniano Román and Eloísa Diez (Intelligence Theory). Through this proposal, the student is linked with skills, abilities and skills; where you not only acquire knowledge, but also learn values so that you can socialize with your knowledge in this changing society. Thus, this proposal contains in the first chapter the planning of the work of professional proficiency; the second, theoretical framework and as the last chapter the curricular programming

Infrared wavefront sensing for adaptive optics assisted Galactic Center observations with the VLT interferometer and GRAVITY: operation and results

This article describes the operation of the near-infrared wavefront sensing based Adaptive Optics (AO) system CIAO. The Coud\'e Infrared Adaptive Optics (CIAO) system is a central auxiliary component of the Very Large Telescope (VLT) interferometer (VLTI). It enables in particular the observations of the Galactic Center (GC) using the GRAVITY instrument. GRAVITY is a highly specialized beam combiner, a device that coherently combines the light of the four 8-m telescopes and finally records interferometric measurements in the K-band on 6 baselines simultaneously. CIAO compensates for phase disturbances caused by atmospheric turbulence, which all four 8 m Unit Telescopes (UT) experience during observation. Each of the four CIAO units generates an almost diffraction-limited image quality at its UT, which ensures that maximum flux of the observed stellar object enters the fibers of the GRAVITY beam combiner. We present CIAO performance data obtained in the first 3 years of operation as a function of weather conditions. We describe how CIAO is configured and used for observations with GRAVITY. In addition, we focus on the outstanding features of the near-infrared sensitive Saphira detector, which is used for the first time on Paranal, and show how it works as a wavefront sensor detector.Comment: 12 pages, 8 figures, accepted for publication in Instruments (open access journal from mdpi

Multiple star systems in the Orion nebula

This is the author accepted manuscript. The final fersion is available from EDP Sciences via the DOI in this record.This work presents an interferometric study of the massive-binary fraction in the Orion Trapezium cluster with the recently comissioned GRAVITY instrument. We observed a total of 16 stars of mainly OB spectral type. We find three previously unknown companions for θ1 Ori B, θ2 Ori B, and θ2 Ori C. We determined a separation for the previously suspected companion of NU Ori. We confirm four companions for θ1 Ori A, θ1 Ori C, θ1 Ori D, and θ2 Ori A, all with substantially improved astrometry and photometric mass estimates. We refined the orbit of the eccentric high-mass binary θ1 Ori C and we are able to derive a new orbit for θ1 Ori D. We find a system mass of 21.7 M⊙ and a period of 53 days. Together with other previously detected companions seen in spectroscopy or direct imaging, eleven of the 16 high-mass stars are multiple systems. We obtain a total number of 22 companions with separations up to 600 AU. The companion fraction of the early B and O stars in our sample is about two, significantly higher than in earlier studies of mostly OB associations. The separation distribution hints toward a bimodality. Such a bimodality has been previously found in A stars, but rarely in OB binaries, which up to this point have been assumed to be mostly compact with a tail of wider companions. We also do not find a substantial population of equal-mass binaries. The observed distribution of mass ratios declines steeply with mass, and like the direct star counts, indicates that our companions follow a standard power law initial mass function. Again, this is in contrast to earlier findings of flat mass ratio distributions in OB associations. We excluded collision as a dominant formation mechanism but find no clear preference for core accretion or competitive accretion.Marie Skłodowska-Curie Grant AgreementFCT-PortugalERC Starting Gran

Design proposal for an application for the sale of spare parts through digital channels

“Moto Spare Parts” es una idea de negocio, una empresa multimarca que comercializa kits de repuestos originales para motocicletas. Asimismo, esta propuesta va en sinergia con el estilo de vida que han adoptado varias personas en Lima Metropolitana. Es por ello que se canaliza la comercialización a través de un aplicativo móvil. En Perú, debido a las medidas de confinamiento (Covid-19), se incrementó el comercio electrónico de productos y como consecuencia el servicio de delivery está en todo su apogeo, sobre todo para aquellos que usan la motocicleta como herramienta de trabajo. Sin embargo, debido al incremento de este servicio, las motocicletas requieren un mantenimiento más frecuente, es por ello que los clientes buscan casas de repuestos o tiendas multimarca confiables. También, buscan reducir el tiempo que les toma adquirir el repuesto y el tiempo de entrega. En relación a ello, se desarrolló el aplicativo móvil que tiene como segmento de clientes mujeres y hombres de 18 a 39 años del NSE B y C de las zonas de 2, 3, y 10 de Lima Metropolitana, quienes son consumidores de repuestos para el mantenimiento de motocicletas y optan por comprar los repuestos a través de plataformas digitales. Para realizar el proyecto se necesitará una inversión de S/ 157,213.00, la cual está compuesta por el aporte de accionistas. Se ofrecerá una tasa de rentabilidad de 14.61% y se espera recuperar la inversión en 2 años."Moto Spare Parts" is a business idea, a multi-brand company that sells original spare parts kits for motorcycles. Additionally, this proposal is in cooperation with the lifestyle adopted by several people in Metropolitan Lima. That is why selling is through mobile applications. In Peru, due to confinement measures (Covid-19), electronic commerce of products increased and so the delivery service is on peak, especially for those who use the motorcycle as a work tool. However, due to the increase in this service, motorcycles require more frequent maintenance, which is why customers look for reliable spare parts houses or multi-brand stores. Also, they look to reduce the time it takes to buy the part and the delivery time. In relation to this, the mobile application was developed, having has as a segment of customers, women, and men between 18 and 39 years of the NSE B and C of the zones 2, 3 and 10 of Metropolitan Lima, who are consumers of spare parts for maintenance of motorcycles and choose to buy spare parts through digital platforms. To develop the project, we will need an investment of S/ 157,213.00 PEN, which is made up of the contribution of shareholders. A 14.61% rate of return will be offered, and the investment is expected to be recovered in the 2 year.Trabajo de investigació

<i>PADI4</i> Haplotypes Contribute to mRNA Expression, the Enzymatic Activity of Peptidyl Arginine Deaminase and Rheumatoid Arthritis Risk in Patients from Western Mexico

Citrullination is catalyzed by the peptidyl arginine deiminase 4 (PAD4) enzyme, encoded by the PADI4 gene. Increased PAD4 activity promotes the onset and progression of rheumatoid arthritis (RA). This study aimed to evaluate the association of PADI4 haplotypes with RA risk, mRNA expression, and the PAD4 activity in patients with RA from Mexico. Methodology: 100 RA patients and 100 control subjects (CS) were included. Genotyping was performed by PCR-RFLP method, PADI4 mRNA expression was quantified by real-time PCR, the contribution of PADI4 alleles (PADI4_89 G>A, PADI4_90 T>C, and PADI4_92 G>C) to mRNA expression by the ASTQ method, and PAD4 activity by HPLC. Also, the anti-CCP and anti-PADI4 antibodies were quantified by ELISA. Results: The three PADI4 polymorphisms were associated with RA susceptibility (OR = 1.72, p = 0.005; OR = 1.62; p = 0.014; OR = 1.69; p = 0.009; respectively). The 89G, 90T, and 92G alleles have a higher relative contribution to PADI4 mRNA expression from RA patients than 89A, 90C, and 92C alleles in RA patients. Moreover, the GTG/GTG haplotype was associated with RA susceptibility (OR = 2.86; p = 0.024). The GTG haplotype was associated with higher PADI4 mRNA expression (p = 0.04) and higher PAD4 enzymatic activity (p = 0.007) in RA patients. Conclusions: The evaluated polymorphisms contribute to PADI4 mRNA expression and the enzymatic activity of PAD4 in leukocytes. Therefore, the GTG haplotype is a genetic risk factor for RA in western Mexico, and is associated with increased PADI4 mRNA expression and higher PAD4 activity in these patients

Integration and bench testing for the GRAVITY Coudé IR adaptive optics (CIAO) wavefront sensor

International audienc

Integration and bench testing for the GRAVITY Coudé IR adaptive optics (CIAO) wavefront sensor

International audienc

Integration and bench testing for the GRAVITY Coudé IR adaptive optics (CIAO) wavefront sensor

International audienc

CIAO: wavefront sensors for GRAVITY

International audienc

CIAO: wavefront sensors for GRAVITY

International audienc