Teaching Competency in the Digital Era in Indonesia, Malaysia and the Philippines

This study investigated the challenges of teaching in the digital environment and identified digital competency among lecturers in higher learning institutions in the digital era. The survey was carried out from April to September 2022 with 155 valid responses among 200 lecturers, 77.5% response rate from private and public higher learning institutions from Indonesia, Malaysia, and the Philippines. PLS-SEM was used to analyse the survey results and hypothesis testing was conducted through bootstrapping. Among the seven hypotheses proposed, six were accepted and one was rejected, which was the development of digital learning resources towards competency teaching in the digital era. Keywords: teaching competency, digital era, higher learning institutions, PLS-SEM eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI

Teaching Competency in the Digital Era in Indonesia, Malaysia and the Philippines

This study investigated the challenges of teaching in the digital environment and identified digital competency among lecturers in higher learning institutions in the digital era. The survey was carried out from April to September 2022 with 155 valid responses among 200 lecturers, 77.5% response rate from private and public higher learning institutions from Indonesia, Malaysia, and the Philippines. PLS-SEM was used to analyse the survey results and hypothesis testing was conducted through bootstrapping. Among the seven hypotheses proposed, six were accepted and one was rejected, which was the development of digital learning resources towards competency teaching in the digital era

Efecto de la interacción genotipo-medio ambiente en pollo de engorda comercial. l. Características productivas a la octava semana de edad (a)

Se evaluó la interacción genotipo medio ambiente en tres líneas de pollo de engorda comercial en cinco localidades, distribuidas en los Estados de Méxic

Eyelid Disorders in Ophthalmology Practice: Results from a Large International Epidemiological Study in Eleven Countries

Purpose: Anecdotal evidence suggests that eyelid disorders are common, although estimates of prevalence vary. The current study determines the prevalence of eyelid disorders, meibomian gland dysfunction (MGD) and related diseases (specifically ocular surface disease) in a population of patients presenting for routine ophthalmologic consultations. Methods: This cross-sectional epidemiologic survey evaluated patients presenting for routine ophthalmic visits. During the consultation an ophthalmologist completed a questionnaire, and each patient underwent an ophthalmic examination and completed a quality of life questionnaire. Results: Three hundred forty-nine ophthalmologists, recruited from 11 countries, provided data on 6525 patients. Patients were predominantly females (61.6%). The mean age of the study population was 57.0 ± 17.6 years. Eyelid disorders were diagnosed in 5109 (78.3%) patients and were statistically associated with

Differential responses of adiposity, inflammation and autonomic function to aerobic versus resistance training in older adults

Background: Increased body fat, autonomic dysfunction and low-grade chronic inflammation are interrelated risk factors implicated in the etiology of several chronic conditions normally presented by older adults. Objective: This study aims to assess the effectiveness of different training protocols on reducing body fat, improving autonomic function, and decreasing low-grade systemic inflammation in community-dwelling elderly adults. Methods: Fifty participants (11 men, 68. ±. 5.5. years) were randomly allocated into resistance or aerobic training or control groups. Evaluations were done at baseline and following the 8-month intervention period on their body composition (assessed by DXA), inflammatory biomarkers (high-sensitivity C-reactive protein [hs-CRP], tumor necrosis-alpha [TNF-. α], interferon-gamma [IFN-γ], interleukins-6 and -10 [IL-6, IL-10]), lipoproteic profile, fasting glycemia, blood pressure, heart rate variability (HRV; frequency and time domains) and aerobic fitness (assessed by six-minute walk distance [6MWD]). A paired t-test was used to detect changes (%δ. =. [(post-test score. -. pretest score). /. pre-test score]. ×. 100) within groups, while between-group differences were analyzed using the one-way ANOVA or General Linear Models. Results: A significant change (δ%) both in total (-. 5.4. ±. 6.3% and -. 3.3. ±. 2.9%, respectively) and central body fat (8.9. ±. 11.3% and -. 4.8. ±. 4.5%) was observed in resistance and aerobic training groups, respectively; along with a change in resting systolic and diastolic blood pressures (-. 9.2. ±. 9.8% and -. 8.5. ±. 9.6%), heart rate (-. 4.6. ±. 6.5%), hs-CRP (-. 18.6. ±. 60.6%), and 6MWD (9.5. ±. 6.9%) in response to aerobic training. Conclusions: The present findings provide further evidence for the benefits of aerobic and resistance training on reducing body fat. Aerobic training was demonstrated to reduce hs-CRP and blood pressure in community-dwelling elderly participants with no serious medical conditions. © 2013 Elsevier Inc

Suberose e doença dos criadores de aves: estudo comparativo do perfil radiológico, funcional e do lavado broncoalveolar

RESUMO: A alveolite alérgica extrínseca (AAE) é uma doença intersticial pulmonar de mediação imunológica, resultando da inalação repetida de vários agentes ambientais. Tem sido descrita heterogeneidade da apresentação clínica e do perfil do líquido de lavagem broncoalveolar (LLBA), possivelmente relacionada com diferentes exposições ocupacionais.O objectivo deste trabalho foi comparar as características clínicas, funcionais, radiológicas e do LLBA de duas das mais frequentes AAE no nosso país: a suberose e a doença de criadores de aves (DCA).Foram estudados 81 doentes com suberose, com média de idades de 38,8±11,3 anos e exposição média de 20,0±10,5 anos e 32 doentes com DCA, com uma média de idades de 46,3±11,8 anos e exposição média de 10,5±1,0 anos.Os doentes com DCA apresentavam mais formas agudas, enquanto as formas subagudas e crónicas predominaram na suberose. A síndroma ventilatória restritiva foi o padrão funcional mais frequente, sendo mais severo na DCA. As opacidades em âvidro despolidoâ foram o padrão mais frequentemente encontrado na tomografia axial computorizada de alta resolução. A normalidade da radiografia de tórax foi mais frequentemente observada na suberose. Ambos os tipos de AAE tinham alveolite linfocítica no LLBA: suberose â 6,6±5,7 x 105 ml-1 células, 58,8±18,9% linfócitos; DCA â 9,0±6,5 x 105 ml-1 células, 61,7±22,2% linfócitos. Apesar de os linfócitos CD8+ do LLBA predominarem em ambas doenças, a percentagem de células CD4+ e a relação CD4/CD8 eram significativamente mais elevadas na DCA (suberose: 0,47±0,33 versus BFD: 1,1±1,5; p <0.005). Para além disso, a celularidade do LLBA e o número de mastócitos eram também significativamente mais elevados na DCA.Em conclusão, a suberose e a doença de criadores de aves são AAE com diferentes perfis clínicos e laboratoriais, sugerindo que, apesar das suas semelhanças fisiopatológicas, diferentes exposições antigénicas podem causar uma diferente dinâmica da resposta imune/inflamatória do pulmão.REV PORT PNEUMOL 2004; X (1): 63-75 ABSTRACT: Extrinsic Allergic Alveolitis (EAA) is an immunologically mediated interstitial lung disease that may result from repeated inhalation of many different environmental agents. Heterogeneity of the clinical presentation and bronchoalveolar lavage profiles has been described, possibly related to different occupational exposures. The aim of our study was to compare bronchoalveolar lavage fluid (BALF), clinical, functional and radiological characteristics of the two most frequent forms of EAA seen in our practice: Suberosis and Bird Fancierâs Disease (BFD).We included 81 patients with Suberosis, with a mean age of 38.8±11.3 years and a mean exposure of 20.0±10.5 years and 32 patients with BFD, with a mean age of 46.3±11.8 years and mean exposure of 10.5±1.0 years.Patients with BFD had more acute forms, while subacute and chronic presentations predominated in Suberosis. Restrictive defect was the most frequent pattern of lung function impairment, and more severe in BFD. Ground glass opacities were the most frequent pattern in high-resolution computed tomography. A normal chest x-ray was more frequently seen in Suberosis. Both types of EAA had lymphocytic alveolitis in BALF: Suberosis 6.6±5.7 x 105 ml-1 cells, 58.8±18.9% lymphocytes; bird fancierâs disease - 9.0±6.5 x 105 ml-1 cells, 61.7±22.2% lymphocytes. Although BALF CD8+ lymphocytes predominated in both diseases, the proportion of CD4+ and CD4/CD8 ratios were significantly higher in Bird Fancierâs Disease (Suberosis: 0.47±0.33 versus BFD: 1.1±1.5; p <0.005). Moreover, BALF cellularity and mast cell counts were also significantly higher in BFD.In conclusion, Suberosis and bird fancierâs disease are EAA with different clinical and laboratory profiles, suggesting that despite their pathophysiological similarities, different antigenic exposures may cause different immune and inflammatory response dynamics in the lung.REV PORT PNEUMOL 2004; X (1): 63-75 Palavras-chave: Lavagem broncoalveolar, TAC-AR, suberose, doença de criadores de aves, Key-words: Bronchoalveolar lavage, HRCT, suberosis, bird fancierâs diseas

Substance P antagonist improves both obesity and asthma in a mouse model

Evidence suggests a causal relationship between obesity and asthma; however, the underlying mechanisms remain unknown. Substance P (SP), involved in neurogenic inflammation by acting through its receptor NK1-R, seems to participate in obese–asthma phenotype in mice. To evaluate the effect of a selective substance P receptor antagonist on a mouse model of diet-induced obesity and asthma. Diet-induced obese Balb/c mice were sensitized and challenged with ovalbumin (OVA) and treated with a selective NK1-R antagonist or placebo. Serum glucose, insulin, IL-6, resistin, and OVA-specific IgE levels were quantified. A score for peribronchial inflammation in lung histology was used. Cells were counted in bronchoalveolar lavage fluid. Adipocyte sizes were measured. Ovalbumin-obese mice treated with NK1-R antagonist had lower weight (P = 0.0002), reduced daily food intake (P = 0.0021), reduced daily energy intake (P = 0.0021), reduced surface adipocyte areas (P < 0.0001), lower serum glucose (P = 0.04), lower serum insulin (P = 0.03), lower serum IL-(P = 0.0022), lower serum resistin (P = 0.0043), lower serum OVA-specific IgE (P = 0.035), and lower peribronchial inflammation score (P < 0.0001) than nontreated OVA-obese mice. We observed an interaction between obesity, allergen sensitization, and treatment with NK1-R antagonist for metabolic and systemic biomarkers, and for allergen sensitization and bronchial inflammation, showing a synergy between these variables. In an experimental model of obesity and asthma in mice, NK1-R blockade improved metabolic and systemic biomarkers, as well as allergen sensitization and bronchial inflammation. These positive effects support a common pathway in the obese–asthma phenotype and highlight SP as a target with potential clinical interest in the obese–asthma epidemics.info:eu-repo/semantics/publishedVersio