2,743 research outputs found

    Does choice of programming language affect student understanding of programming concepts in a first year engineering course?

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    Most undergraduate engineering curricula include computer programming to some degree,introducing a structured language such as C, or a computational system such as MATLAB, or both. Many of these curricula include programming in first year engineering courses, integrating the solution of simple engineering problems with an introduction to programming concepts. In line with this practice, Roger Williams University has included an introduction to programming as a part of the first year engineering curriculum for many years. However, recent industry and pedagogical trends have motivated the switch from a structured language (VBA) to a computational system (MATLAB). As a part of the pilot run of this change,the course instructors felt that it would be worthwhile to verify that changing the programming language did not negatively affect students’ ability to understand key programming concepts. In particular it was appropriate to explore students’ ability to translate word problems into computer programs containing inputs, decision statements, computational processes, and outputs. To test the hypothesis that programming language does not affect students’ ability to understand programming concepts, students from consecutive years were given the same homework assignment, with the first cohort using VBA and the second using MATLAB to solve the assignment. A rubric was developed which allowed the investigators to rate assignments independent of programming language. Results from this study indicate that there is not a significant impact of the change in programming language. These results suggest that the choice of programming language likely does not matter for student understanding of programming concepts. Course instructors should feel free to select programming language based on other factors, such as market demand, cost, or the availability of pedagogical resources

    Electron Nuclear Double Resonance of the Chlorophyll Triplet State in the Water-Soluble Chlorophyll Protein from Brassica oleracea: Investigation of the Effect of the Binding Site on the Hyperfine Couplings

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    An investigation of the photoexcited triplet state of chlorophyll (Chl) a in the water-soluble chlorophyll protein (WSCP) of Brassica oleracea has been carried out by means of electron-nuclear double resonance (ENDOR), achieving a complete assignment of the observed hyperfine couplings corresponding to methine protons and methyl groups of Chl a triplet state. The triplet-state properties, and in particular the hyperfine couplings, were found to be similar to those previously reported for Chl a in the WSCP of Lepidium virginicum. Therefore, the porphyrin ring deformation observed in Brassica oleracea WSCP seems to only slightly affect the spin density of 3Chl a. This may be relevant when considering the robustness of triplet\u2013triplet energy transfer mechanisms, relying on wavefunction overlap, in systems, such as the photosynthetic light-harvesting complexes, in which Chl triplet states with distorted geometries are involved

    Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma

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    Ependymal tumors constitute a clinicopathologically heterogeneous group of brain tumors. They vary in regard to their age at first symptom, localization, morphology and prognosis. Genetic data also suggests heterogeneity. We define a newly recognized subset of ependymal tumors, the trisomy 19 ependymoma. Histologically, they are compact lesions characterized by a rich branched capillary network amongst which tumoral cells are regularly distributed. When containing clear cells they are called clear cell ependymoma. Most trisomy 19 ependymomas are supratentorial WHO grade III tumors of the young. Genetically, they are associated with trisomy 19, and frequently with a deletion of 13q21.31-31.2, three copies of 11q13.3-13.4, and/or deletions on chromosome 9. These altered chromosomal regions are indicative of genes and pathways involved in trisomy 19 ependymoma tumorigenesis. Recognition of this genetico-histological entity allows better understanding and dissection of ependymal tumors

    Pressure Evolution of a Field Induced Fermi Surface Reconstruction and of the Neel Critical Field in CeIn3

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    We report high-pressure skin depth measurements on the heavy fermion material CeIn3 in magnetic fields up to 64 T using a self-resonant tank circuit based on a tunnel diode oscillator. At ambient pressure, an anomaly in the skin depth is seen at 45 T. The field where this anomaly occurs decreases with applied pressure until approximately 1.0 GPa, where it begins to increase before merging with the antiferromagnetic phase boundary. Possible origins for this transport anomaly are explored in terms of a Fermi surface reconstruction. The critical magnetic field at which the Neel ordered phase is suppressed is also mapped as a function of pressure and extrapolates to the previous ambient pressure measurements at high magnetic fields and high pressure measurements at zero magnetic field.Comment: 15 pages, 5 figure

    Velocity-selective direct frequency-comb spectroscopy of atomic vapors

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    We present an experimental and theoretical investigation of two-photon direct frequency-comb spectroscopy performed through velocity-selective excitation. In particular, we explore the effect of repetition rate on the 5S1/25D3/2,5/2\textrm{5S}_{1/2}\rightarrow \textrm{5D}_{3/2, 5/2} two-photon transitions excited in a rubidium atomic vapor cell. The transitions occur via step-wise excitation through the 5P1/2,3/2\textrm{5P}_{1/2, 3/2} states by use of the direct output of an optical frequency comb. Experiments were performed with two different frequency combs, one with a repetition rate of 925\approx 925 MHz and one with a repetition rate of 250\approx 250 MHz. The experimental spectra are compared to each other and to a theoretical model.Comment: 10 pages, 7 figure

    Baseline corticosterone in wintering marine birds: Methodological considerations and ecological patterns

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    Previous studies have related levels of plasma corticosterone (CORT) of seabirds to variation in foraging conditions during the breeding period, but it is unclear whether similar relationships between foraging conditions and baseline CORT exist during other life stages. We validated methods for identifying baseline CORT of lethally sampled birds and assessed variation in baseline CORT relative to winter habitat conditions. We collected free-living white-winged scoters (Melanitta fusca) at four wintering sites during December and February. We found increasing CORT values beyond 3 min after time since flush (the duration between initial flush and death), presumably reflecting acute stress responses. Our results demonstrate that it is possible to obtain baseline CORT from lethally sampled birds if the time from initial flush until death is measured. Our study sites varied appreciably in exposure to wind and waves, predation danger, diving depths, and the fraction of preferred foods in scoter diets. Despite these habitat differences, baseline CORT did not vary across sites or winter periods. We interpret this lack of variation as evidence that birds select wintering areas where they can successfully manage site-specific costs and maintain physiological homeostasis. © 2013 by The University of Chicago. All rights reserved

    Baseline Corticosterone in Wintering Marine Birds: Methodological Considerations and Ecological Patterns

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    Previous studies have related levels of plasma corticosterone (CORT) of seabirds to variation in foraging conditions during the breeding period, but it is unclear whether similar relationships between foraging conditions and baseline CORT exist during other life stages. We validated methods for identifying baseline CORT of lethally sampled birds and assessed variation in baseline CORT relative to winter habitat conditions. We collected free-living white-winged scoters (Melanitta fusca) at four wintering sites during December and February. We found increasing CORT values beyond 3 min after time since flush (the duration between initial flush and death), presumably reflecting acute stress responses. Our results demonstrate that it is possible to obtain baseline CORT from lethally sampled birds if the time from initial flush until death is measured. Our study sites varied appreciably in exposure to wind and waves, predation danger, diving depths, and the fraction of preferred foods in scoter diets. Despite these habitat differences, baseline CORT did not vary across sites or winter periods. We interpret this lack of variation as evidence that birds select wintering areas where they can successfully manage site-specific costs and maintain physiological homeostasis

    Unusual metamagnetism in CeIrIn5_5

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    We report a high field investigation (up to 45 T) of the metamagnetic transition in CeIrIn5_5 with resistivity and de-Haas-van-Alphen (dHvA) effect measurements in the temperature range 0.03-1 K. As the magnetic field is increased the resistivity increases, reaches a maximum at the metamagnetic critical field, and falls precipitously for fields just above the transition, while the amplitude of all measurable dHvA frequencies are significantly attenuated near the metamagnetic critical field. However, the dHvA frequencies and cyclotron masses are not substantially altered by the transition. In the low field state, the resistivity is observed to increase toward low temperatures in a singular fashion, a behavior that is rapidly suppressed above the transition. Instead, in the high field state, the resistivity monotonically increases with temperature with a dependence that is more singular than the iconic Fermi-liquid, temperature-squared, behavior. Both the damping of the dHvA amplitudes and the increased resistivity near the metamagnetic critical field indicate an increased scattering rate for charge carriers consistent with critical fluctuation scattering in proximity to a phase transition. The dHvA amplitudes do not uniformly recover above the critical field, with some hole-like orbits being entirely suppressed at high fields. These changes, taken as a whole, suggest that the metamagnetic transition in CeIrIn5_5 is associated with the polarization and localization of the heaviest of quasiparticles on the hole-like Fermi surface.Comment: 29 pages, 9 figure

    Migraine and vascular disease biomarkers: A population-based case-control study.

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    Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population. Methods Participants (300 women, 117 men) were recruited as a part of the Dutch CAMERA 1 (Cerebral Abnormalities in Migraine, an Epidemiologic Risk Analysis) study. Participants were aged 30-60 (mean 48) years, 155 migraine had with aura (MA), 128 migraine without aura (MO), and 134 were controls with no severe headaches. Plasma concentrations of fibrinogen, Factor II, D-dimer, high sensitivity C-reactive protein (hs-CRP), and von Willebrand factor antigen were compared between groups, also stratifying by sex. Results Fibrinogen and hs-CRP were elevated in migraineurs compared to controls. In logistic regression analyses, MO and MA had increased likelihood of elevated fibrinogen, and MA had increased likelihood of elevated Factor II and hs-CRP. Fibrinogen and Factor II were associated with MA in women but not men. In the migraine subgroup, the total number of years of aura, but not headache, predicted elevated hs-CRP, and the average number of aura, but not headache, attacks predicted all biomarkers but Factor II. Conclusions Elevated vascular biomarkers were associated with migraine, particularly MA, as well as with years of aura and number of aura attacks
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