Two new catalogs of blazar candidates in the WISE infrared sky

We present two catalogs of radio-loud candidate blazars whose WISE mid-infrared colors are selected to be consistent with the colors of confirmed gamma-ray emitting blazars. The first catalog is the improved and expanded release of the WIBRaLS catalog presented by D'Abrusco et al. (2014): it includes sources detected in all four WISE filters, spatially cross-matched with radio source in one of three radio surveys and radio-loud based on their q22 spectral parameter. WIBRaLS2 includes 9541 sources classified as BL Lacs, FSRQs or mixed candidates based on their WISE colors. The second catalog, called KDEBLLACS, based on a new selection technique, contains 5579 candidate BL Lacs extracted from the population of WISE sources detected in the first three WISE passbands ([3.4], [4.6] and [12]) only, whose mid-infrared colors are similar to those of confirmed, gamma-ray BL Lacs. KDBLLACS members area also required to have a radio counterpart and be radio-loud based on the parameter q12, defined similarly to q22 used for the WIBRaLS2. We describe the properties of these catalogs and compare them with the largest samples of confirmed and candidate blazars in the literature. We crossmatch the two new catalogs with the most recent catalogs of gamma-ray sources detected by Fermi LAT instrument. Since spectroscopic observations of candidate blazars from the first WIBRaLS catalog within the uncertainty regions of gamma-ray unassociated sources confirmed that ~90% of these candidates are blazars, we anticipate that these new catalogs will play again an important role in the identification of the gamma-ray sky.Comment: 20 pages, 7 figures. Accepted for publication in The Astrophysical Journal Supplement Serie

3C 17: The BCG of a Galaxy Cluster at z = 0.22

Gemini Multi Object Spectrograph medium-resolution spectra and photometric data of 39 objects in the field of the radio galaxy 3C 17 are presented. Based on the new data, a previously uncataloged cluster of galaxies is identified at a mean redshift of z = 0.220 ± 0.003, a projected virial radius of 0.37 Mpc, and a velocity dispersion of σ v = 821 ± 171 km s-1. The brightest member of this cluster is 3C 17, with M r = -22.45 mag. The surface brightness profile of 3C 17 is best fit with two components (Exponential + Sérsic) characteristic of brightest cluster galaxies. The spectrum of 3C 17 is dominated by broad emission lines Hα + N[ ii] and Hβ + [O iii]. Analysis of Chandra data shows extended emission around the cluster core that supports the existence of hot gas cospatial with 3C 17. The discovery of a cluster of galaxies around 3C 17 better explains the sharply bent morphology of the radio jet given that it propagates through a dense intracluster medium.Fil: Madrid, Juan P.. Commonwealth Scientific And Industrial Research Organization; AustraliaFil: Donzelli, Carlos Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Rodríguez-Ardila, Alberto. Laboratorio Nacional de Astrofisica; Brasil. Instituto Astrofisico de Canarias; EspañaFil: Paggi, Alessandro. Istituto Nazionale di Astrofisica; ItaliaFil: Massaro, Francesco. Istituto Nazionale di Astrofisica; ItaliaFil: Schirmer, Mischa. Gemini Observatorysouthern Operations Center; Chile. Max Planck Institute For Astronomy; Alemani

SI113, a Specific Inhibitor of the Sgk1 Kinase Activity that Counteracts Cancer Cell Proliferation

Background/Aims: Published observations on serum and glucocorticoid regulated kinase 1 (Sgk1) knockout murine models and Sgk1-specific RNA silencing in the RKO human colon carcinoma cell line point to this kinase as a central player in colon carcinogenesis and in resistance to taxanes. Methods: By in vitro kinase activity inhibition assays, cell cycle and viability analysis in human cancer model systems, we describe the biologic effects of a recently identified kinase inhibitor, SI113, characterized by a substituted pyrazolo[3,4-d]pyrimidine scaffold, that shows specificity for Sgk1. Results: SI113 was able to inhibit in vitro cell growth in cancer cells derived from tumors with different origins. In RKO cells, this kinase inhibitor blocked insulin-dependent phosphorylation of the Sgk1 substrate Mdm2, the main regulator of p53 protein stability, and induced necrosis and apoptosis when used as a single agent. Finally, SI113 potentiated the effects of paclitaxel on cell viability. Conclusion: Since SI113 appears to be effective in inducing cell death in RKO cells, potentiating paclitaxel sensitivity, we believe that this new molecule could be efficiently employed, alone or in combination with paclitaxel, in colon cancer chemotherapy

Powerful Radio Sources in the Southern Sky. II. A Swift X-Ray Perspective

We recently constructed the G4Jy-3CRE, a catalog of extragalactic radio sources based on the GLEAM 4-Jy (G4Jy) sample, with the aim of increasing the number of powerful radio galaxies and quasars with similar selection criteria to those of the revised release of the Third Cambridge Catalog (3CR). The G4Jy-3CRE consists of a total of 264 radio sources mainly visible from the Southern Hemisphere. Here, we present an initial X-ray analysis of 89 G4Jy-3CRE radio sources with archival X-ray observations from the Neil Gehrels Swift Observatory. We reduced a total of 624 Swift observations, for about 0.9 Ms of integrated exposure time. We found X-ray counterparts for 59 radio sources belonging to the G4Jy-3CRE, nine of them showing extended X-ray emission. The remaining 30 sources do not show any X-ray emission associated with their radio cores. Our analysis demonstrates that X-ray snapshot observations, even if lacking uniform exposure times, as those carried out with Swift, allow us to (i) verify and/or refine the host galaxy identification; (ii) discover the extended X-ray emission around radio galaxies of the intracluster medium when harbored in galaxy clusters, as the case of G4Jy 1518 and G4Jy 1664; and (iii) detect X-ray radiation arising from their radio lobes, as for G4Jy 1863

Powerful Radio Sources in the Southern Sky. I. Optical Identifications

Since the early sixties, our view of radio galaxies and quasars has been drastically shaped by discoveries made thanks to observations of radio sources listed in the Third Cambridge Catalog and its revised version (3CR). However, the largest fraction of data collected to date on 3CR sources was performed with relatively old instruments, rarely repeated and/or updated. Importantly, the 3CR contains only objects located in the Northern Hemisphere, thus having limited access to new and innovative astronomical facilities. To mitigate these limitations, we present a new catalog of powerful radio sources visible from the Southern Hemisphere, extracted from the GLEAM 4 Jy (G4Jy) catalog and based on equivalent selection criteria as the 3CR. This new catalog, named G4Jy-3CRE, where the E stands for equivalent, lists a total of 264 sources at decl. below −5° and with 9 Jy limiting sensitivity at ∼178 MHz. We explored archival radio maps obtained with different surveys and compared them with optical images available in the Pan-STARRS, DES, and DSS databases to search for optical counterparts of their radio cores. We compared mid-infrared counterparts, originally associated in the G4Jy, with the optical ones identified here, and we present results of a vast literature search carried out to collect redshift estimates for all G4Jy-3CRE sources resulting in a total of 145 reliable z measurements

Aberrant salience in cannabis-induced psychosis: a comparative study

© 2024 The Author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY), https://creativecommons.org/licenses/by/4.0/Background: Natural Cannabis (NC) and Synthetic Cannabinoids (SCs) use can increase the risk and exacerbate the course of psychotic disorders. These could be influenced by the Aberrant Salience (AS) construct. It refers to an excess of attribution of meaning to stimuli that are otherwise regarded as neutral, thereby transform them into adverse, dangerous, or mysterious entities. This leads the patient to engage in aberrant and consequently incorrect interpretative efforts concerning the normal perception of reality and its relationship with our analytical abilities. AS appears to play a significant role in the onset and perpetuation of psychotic disorders. The internal conflict arising from aberrant attributions of significance leads to delusional thoughts, ultimately culminating in the establishment of a self-sustaining psychosis. Aims: To examine the differences between psychoses course not associated with cannabis use and those associated with NC-use and SCs-use, in terms of psychotic and dissociative symptoms, AS, global functioning and suicidal ideation. Methods: A sample of 62 patients with First Episode Psychosis (FEP) was divided into 3 groups: non cannabis users (non-users, N = 20); NC-users or rather Delta-9-tetrahydrocannabinol (THC) users (THC-users, N = 21); SCs-users, commonly referred to as SPICE-users (SPICE-users, N = 20). Each group underwent assessments at the onset of psychotic symptoms, as well as at the 3 months and 6 months marks, utilizing a range of psychopathological scales. These included the Positive and Negative Syndrome Scale (PANSS) for investigating psychotic symptoms, the Global Assessment of Functioning (GAF) scale for assessing overall functioning, the Dissociative Experiences Scale (DES-II) for measuring dissociative symptoms, the Scale for Suicide Ideation (SSI) for evaluating suicidal ideation and the Aberrant Salience Inventory (ASI) scale for gauging AS. Results: SPICE-users showed more severe and persistent positive symptoms, while negative symptoms were mostly represented among non-users. Non-users showed better recovery than SPICE-users in global functioning. All groups showed a decrease in both ASI scores and subscale scores. SPICE-users exhibited higher global AS scores and less improvement in this aspect compared to other groups. Conclusion: This study may help understanding the role of AS in both non-substance-related and substance-induced psychosis. This knowledge may lead clinician to a better diagnosis and identify patient-tailored psychopharmacological treatment.Peer reviewe

Powerful Yet Lonely: Is 3C 297 a High-redshift Fossil Group?

The environment of the high-redshift (z = 1.408), powerful radio-loud galaxy 3C 297 has several distinctive features of a galaxy cluster. Among them, a characteristic halo of hot gas revealed by Chandra X-ray observations. In addition, a radio map obtained with the Very Large Array shows a bright hotspot in the northwestern direction, created by the interaction of the active galactic nucleus (AGN) jet arising from 3C 297 with its environment. In the X-ray images, emission cospatial with the northwestern radio lobe is detected, and peaks at the position of the radio hotspot. The extended, complex X-ray emission observed with our new Chandra data is largely unrelated to its radio structure. Despite having attributes of a galaxy cluster, no companion galaxies have been identified from 39 new spectra of neighboring targets of 3C 297 obtained with the Gemini Multi-Object Spectrograph. None of the 19 galaxies for which a redshift was determined lies at the same distance as 3C 297. The optical spectral analysis of the new Gemini spectrum of 3C 297 reveals an isolated Type II radio-loud AGN. We also detected line broadening in [O ii] λ3728 with a FWHM about 1700 km s−1 and possible line shifts of up to 500–600 km s−1. We postulate that the host galaxy of 3C 297 is a fossil group, in which most of the stellar mass has merged into a single object, leaving behind an X-ray halo

Optical characterization of WISE selected blazar candidates

Context. Over the last decade more than five thousand γ-ray sources have been detected by the Large Area Telescope (LAT) onboard the Fermi Gamma-ray Space Telescope. Given the positional uncertainty of the telescope, nearly 30% of these sources remain without an obvious counterpart at lower energies. This has motivated the release of new catalogs of γ-ray counterpart candidates and several follow up campaigns in the last decade. Aims. Recently, two new catalogs of blazar candidates were released. These are the improved and expanded version of the WISE Blazar-Like Radio-Loud Sources (WIBRaLS2) catalog and the Kernel Density Estimation selected candidate BL Lacs (KDEBLLACS) catalog, both selecting blazar-like sources based on their infrared colors from the Wide-field Infrared Survey Explorer (WISE). In this work we characterize these two catalogs, clarifying the true nature of their sources based on their optical spectra from SDSS data release 15, thus testing their efficiency in selecting true blazars. Methods. We first selected all WIBRaLS2 and KDEBLLACS sources with available optical spectra in the footprint of Sloan Digital Sky Survey data release 15. We then analyzed these spectra to verify the nature of each selected candidate and to measure the fraction of the catalogs composed by spectroscopically confirmed blazars. Finally, we evaluated the impact of selection effects, especially those related to optical colors of WIBRaLS2/KDEBLLACS sources and their optical magnitude distributions. Results. We found that at least ∼30% of each catalog is made up of confirmed blazars, with quasars being the major contaminants in the case of WIBRaLS2 (≈58%) and normal galaxies in the case of KDEBLLACS (≈38.2%). The spectral analysis also allowed us to identify the nature of 11 blazar candidates of uncertain type (BCUs) from the Fermi-LAT fourth Point Source Catalog (4FGL) and to find 25 new BL Lac objects.Fil: de Menezes, Raniere. Universidade Do Sao Paulo. Instituto Astronomia, Geofísica E Ciencias Atmosfericas. Departamento de Astronomia; Brasil. Università degli Studi di Torino; ItaliaFil: Peña Herazo, Harold A.. Instituto Nacional de Astrofísica; México. Università di Torino; Italia. Istituto Nazionale Di Fisica Nucleare.; Italia. Osservatorio Astrofisico di Torino; ItaliaFil: Marchesini, Ezequiel Joaquín. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Astrofísica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas. Instituto de Astrofísica La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; Argentina. Istituto Nazionale Di Fisica Nucleare.; Italia. Università di Torino; ItaliaFil: D´Abrusco, Raffaele. Harvard-Smithsonian Center for Astrophysics; Estados UnidosFil: Masetti, Nicola. Osservatorio di Astrofisica e Scienza dello Spazio; Italia. Universidad Andrés Bello; ChileFil: Nemmen, Rodrigo. Universidade Do Sao Paulo. Instituto Astronomia, Geofísica E Ciencias Atmosfericas. Departamento de Astronomia; BrasilFil: Massaro, Francesco. Università di Torino; Italia. Istituto Nazionale Di Fisica Nucleare.; Italia. Osservatorio Astrofisico di Torino; Italia. Consorzio Interuniversitario per la Fisica Spaziale ; ItaliaFil: Ricci, Federica. Pontificia Universidad Católica de Chile; ChileFil: Landoni, Marco. Osservatorio Astronomico di Brera; ItaliaFil: Paggi, Alessandro. Università di Torino; ItaliaFil: Smith, Howard A.. Harvard-Smithsonian Center for Astrophysics; Estados Unido