Collections as Data: Implications for Enclosure

In recent years a growing amount of interest has been dedicated to collections as data. A collections as data paradigm seeks to foster an expanded set of research, pedagogical, and artistic potential predicated on the computational use of cultural heritage collections. Collections as data raises the question of what it might mean to treat digitized and born digital collections as data rather than simple surrogates of physical objects or static representations of digital experience

Large scale anisotropies on halo infall

We perform a statistical analysis of the peculiar velocity field around dark matter haloes in numerical simulations. We examine different properties of the infall of material onto haloes and its relation to central halo shapes and the shape of the large scale surrounding regions (LSSR). We find that the amplitude of the infall velocity field along the halo shape minor axis is larger than that along the major axis. This is consistent for general triaxial haloes, and for both prolate and oblate systems. We also report a strong anisotropy of the velocity field along the principal axes of the LSSR. The infall velocity field around dark matter haloes reaches a maximum value along the direction of the minor axis of the LSSR, whereas along the direction of its major axis, it exhibits the smallest velocities. We also analyse the dependence of the matter velocity field on the local environment. The amplitude of the infall velocity at high local density regions is larger than at low local density regions. The velocity field tends to be more laminar along the direction towards the minor axis of the LSSR, where the mean ratio between flow velocity and velocity dispersion is of order unity and nearly constant up to scales of 15 Mpc/h. We also detect anisotropies in the outflowing component of the velocity field, showing a maximum amplitude along the surrounding LSSR major axis.Comment: 12 pages, 9 figures, accepted for publication in Monthly Notices of the Royal Astronomical Societ

High-resolution isotope-shift spectroscopy of Cd I

We present absolute frequency measurements of the 1P1←1S0 (229nm) and 3P1←1S0 (326nm) transitions for all naturally occurring isotopes of cadmium. The isotope shifts and hyperfine intervals of the fermionic isotopes are determined with an accuracy of 3.3MHz. We find that quantum interference in the laser-induced fluorescence spectra of the 1P1←1S0 transition causes an error of up to 29(5)MHz in determining the hyperfine splitting, when not accounted for with an appropriate model. Using a King-plot analysis, we extract the field- and mass-shift parameters and determine nuclear charge radius differences for the fermions. The lifetime of the 1P1 state is determined to be 1.60(5)ns by measuring the natural linewidth of the 1P1←1S0 transition. These results resolve significant discrepancies among previous measurements

MTF1, a classic metal sensing transcription factor, promotes myogenesis in response to copper [preprint]

MTF1 is a conserved metal-binding transcription factor in eukaryotes that binds to conserved DNA sequence motifs, termed metal response elements (MREs). MTF1 responds to metal excess and deprivation, protects cells from oxidative and hypoxic stresses, and is required for embryonic development in vertebrates. We used multiple strategies to identify an unappreciated role for MTF1 and copper (Cu) in cell differentiation. Upon initiation of myogenesis from primary myoblasts, MTF1 expression increased, as did nuclear localization. Mtf1 knockdown impaired differentiation, while addition of non-toxic concentrations of Cu+ enhanced MTF1 expression and promoted myogenesis. Cu+ bound stoichiometrically to a C-terminus tetra-cysteine of MTF1. MTF1 bound to chromatin at the promoter regions of myogenic genes and binding was stimulated by copper. MTF1 formed a complex with MyoD at myogenic promoters, the master transcriptional regulator of the myogenic lineage. These studies establish novel mechanisms by which copper and MTF1 regulate gene expression in myoblast differentiation

Galileons as Wess-Zumino Terms

We show that the galileons can be thought of as Wess-Zumino terms for the spontaneous breaking of space-time symmetries. Wess-Zumino terms are terms which are not captured by the coset construction for phenomenological Lagrangians with broken symmetries. Rather they are, in d space-time dimensions, d-form potentials for (d+1)-forms which are non-trivial co-cycles in Lie algebra cohomology of the full symmetry group relative to the unbroken symmetry group. We introduce the galileon algebras and construct the non-trivial (d+1)-form co-cycles, showing that the presence of galileons and multi-galileons in all dimensions is counted by the dimensions of particular Lie algebra cohomology groups. We also discuss the DBI and conformal galileons from this point of view, showing that they are not Wess-Zumino terms, with one exception in each case.Comment: 49 pages. v2 minor changes, version appearing in JHE

Follow-up observations at 16 and 33 GHz of extragalactic sources from WMAP 3-year data: I - Spectral properties

We present follow-up observations of 97 point sources from the Wilkinson Microwave Anisotropy Probe (WMAP) 3-year data, contained within the New Extragalactic WMAP Point Source (NEWPS) catalogue between declinations of -4 and +60 degrees; the sources form a flux-density-limited sample complete to 1.1 Jy (approximately 5 sigma) at 33 GHz. Our observations were made at 16 GHz using the Arcminute Microkelvin Imager (AMI) and at 33 GHz with the Very Small Array (VSA). 94 of the sources have reliable, simultaneous -- typically a few minutes apart -- observations with both telescopes. The spectra between 13.9 and 33.75 GHz are very different from those of bright sources at low frequency: 44 per cent have rising spectra (alpha < 0.0), where flux density is proportional to frequency^-alpha, and 93 per cent have spectra with alpha < 0.5; the median spectral index is 0.04. For the brighter sources, the agreement between VSA and WMAP 33-GHz flux densities averaged over sources is very good. However, for the fainter sources, the VSA tends to measure lower values for the flux densities than WMAP. We suggest that the main cause of this effect is Eddington bias arising from variability.Comment: 12 pages, 13 figures, submitted to MNRA