The Three-step Synthesis of 2,6-Dinitro-4-methylaniline

The Three-step Synthesis of 2,6-Dinitro-4-methylaniline Padao Pha, Stephani Ly This experiment entails the three-step synthesis of 2,6-Dinitro-4-methylaniline from p-toluiodine. P-toluidine was tosylated using tosyl chloride. The subsequent product was then dinitrated with nitric acid and then sulfonated using sulfuric acid to yield 2,6-dinitro-4-methylaniline. While p-toluiodine is known as a suspected cancer agent, 2,6-Dinitro-4-methylaniline is believed to have possible medicinal purposes making it important for future health applications. This synthesis was made more green by replacing sodium hydroxide with ethanol in step one. This is “greener” because ethanol is less corrosive and less health hazardous

Brazil, Czech Republic Encounter of Puppets Benedito and Pimprle, Study of Cultural Encounter of Two Styles of Puppet Theatre

Práce zamýšlí ukázat střet brazilské a české kultury prostřednictvím analýzy a srovnání forem loutkového divadla "mamulengo" z Brazílie (Recife, Pernambuco) a české tradiční lidové loutky. kad ý ze směrů byl ovlivněn jinými podněty a má svou vlastní historii, oba se vyznačují velmi specifickými rysy a výraznými osobnostmi. Střet těchto kultur lze nalézt i v mé práci s loutkami, kteou jsem začal v Brazílii a nyní v ní pokračuji v České republice. Jak výroba, tak i můj způsob přemýšlení o divadle, se během posledních tří let změnily na základě mého magisterského studia na DAMU pod veedním Petra Matáska. Mé zkušenosti z různých festivalů, workshopů a spolupráce se skupinami jako Bread and Puppets jsou popsány v práci. Dále se zaměřím na celkový výsledek této práce a podrobnosti ohledně projektů. Tato práce, stejně jako čas, který jsem věnoval výzkumu, je z velké části zaměřena na hledání mon ostí a zkoušení s marionetami, přípravu a zdokonalení mého uměleckého jazyka. Vzhledem k tomu, e nadále iji a tvořím projekty v Evropě, v mé práci lze najít třetí směr, ani brazilský, ani český - jde o střet dvou škol a způsobů přemýšlení

Brazil, Czech Republic Encounter of Puppets Benedito and Pimprle, Study of Cultural Encounter of Two Styles of Puppet Theatre

The thesis aims to show the match between Czech and Brazilian culture through the analize and comparison between forms of puppet theater Recife Pernambuco Brazil Czech puppet named mamulengo and folkloric. With different histories and influences the two theaters have characteristics very peculiar and remarkable characters. The encounter between these cultures is also the moment in which I developed a work of dolls in Brazil and now in the Czech Republic. As the construction and form of the theater thinking changed in those three years in a master working with my tutor in Pert Matasek DAMU. My experiences in various festivals and workshops and livings with groups like Bread and Puppets are narrated in the thesis. All this result and the detailed design and conclusion will be focused in this work. This thesis and that time devoted to this research were largely devoted to research and practice of puppet making and improving my language as puppeteer. To continue living and developing projects in Europe makes me transmute into a third dimension, or Brazilian or Czech but a gathering of schools and ways of thinking. A tese visa mostrar o encontro entre a cultura brasileira e tcheca atraves da analize e comparacao entre as formas de teatro de bonecos de Recife Pernambuco Brasil chamado mamulengo e o boneco tcheco folclorico. Com historias e influencias diferentes os dois teatros tem caracteristicas muito peculiares e personagens marcantes. O encontro entre essas culturas se da tambem no momento que eu que desenvolvia um trabalho de bonecos no Brasil e agora na Republica Tcheca. Como a construcao e forma de pensar o teatro modificaram nesses 3 anos de mestrado em um trabalho conjunto com Pert Matasek meu tutor na DAMU. As minhas experiencias em diversos festivais e workshops e vivencias com grupos como Bread and Puppets são narrados na tese. Todo esse resultado e o detalhamento dos projetos e conclusao serao enfocados nesse trabalho . Essa tese e esse tempo dedicado a essa pesquisa foram em grande parte dedicado a pesquisa e pratica da marionete , confeccao e aprimoramento da minha linguagem como marionetista. Ao continuar morando e desenvolvendo projetos na europa me faz transmutar em uma terceira vertente, nem brasileira, nem tcheca mas um encontro de escolas e formas de pensar

A Comprehensive Review of the Genetic and Epigenetic Contributions to the Development of Fibromyalgia

This narrative review summarizes the current knowledge of the genetic and epigenetic contributions to the development of fibromyalgia (FM). Although there is no single gene that results in the development of FM, this study reveals that certain polymorphisms in genes involved in the catecholaminergic pathway, the serotonergic pathway, pain processing, oxidative stress, and inflammation may influence susceptibility to FM and the severity of its symptoms. Furthermore, epigenetic changes at the DNA level may lead to the development of FM. Likewise, microRNAs may impact the expression of certain proteins that lead to the worsening of FM-associated symptoms