Studies on the June 23, 2010 north Ottawa M W 5.2 earthquake and vicinity seismicity

The basic parameters for the earthquake with a moment magnitude (M W) of 5. 2 on the 23rd of June 2010 have been investigated. The earthquake occurred on a hidden fault in the northwest direction about 60 km north-northeast of Ottawa in the Wester

Deglacial to Paraglacial History of the Lake Saint-Jean Lowlands: A Geomorphological Perspective

International audienceThe Lake Saint-Jean lowland is a particular area in eastern Canada as it constitutes an important Late Quaternary depocenter compared with other surrounding onshore regions. Here, the recent literature about the Late Quaternary history of the Lake Saint-Jean depocenter from the glaciated period to present-day is summarized; subsequently, we present some preserved landscape features that record such history

Microtubule Organization and Microtubule-Associated Proteins (MAPs)

Dendrites have a unique microtubule organization. In vertebrates, dendritic microtubules are organized in antiparallel bundles, oriented with their plus ends either pointing away or toward the soma. The mixed microtubule arrays control intracellular trafficking and local signaling pathways, and are essential for dendrite development and function. The organization of microtubule arrays largely depends on the combined function of different microtubule regulatory factors or generally named microtubule-associated proteins (MAPs). Classical MAPs, also called structural MAPs, were identified more than 20 years ago based on their ability to bind to and copurify with microtubules. Most classical MAPs bind along the microtubule lattice and regulate microtubule polymerization, bundling, and stabilization. Recent evidences suggest that classical MAPs also guide motor protein transport, interact with the actin cytoskeleton, and act in various neuronal signaling networks. Here, we give an overview of microtubule organization in dendrites and the role of classical MAPs in dendrite development, dendritic spine formation, and synaptic plasticity