420 research outputs found

    Isotope Shifts of the 6d\,^2D3/2 _{3/2}\, - 7p\,^2P1/2 _{1/2}\, Transition in Trapped Short-Lived 209−214^{209-214}Ra+^+

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    Laser spectroscopy of short-lived radium isotopes in a linear Paul trap has been performed. The isotope shifts of the 6d\,^2D3/2 _{3/2}\, - 7p\,^2P1/2 _{1/2}\, transition in 209−214^{209-214}Ra+^+ were measured, which are sensitive to the short range part of the atomic wavefunctions. The results are essential experimental input for improving the precision of atomic structure calculation. This is indispensable for parity violation in Ra+^+ aiming at the determination of the weak mixing angle.Comment: Accepted for publication in Physical Review A as a Rapid Communicatio

    Toposseqüência de solos cultivada com milho no estado de Sergipe.

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    O oeste de Sergipe vem se destacando na produção de milho numa extensa área de solos férteis com boas características edáficas. A potencialidade e extensão dos solos, bem como a necessidade de introdução de técnicas agrícolas e avaliação dos resultados das pesquisas ali desenvolvidas tanto para seu melhor aproveitamento agrícola, quanto para a preservação ambiental, justificam o estudo pormenorizado da área. O objetivo deste trabalho foi estudar uma toposseqüência de solos característica da região, cultivados com milho em regime dependente de chuvas, buscando interpretar sua dinâmica a fim de aportar subsídios para seu melhor manejo, visando a sustentabilidade dos cultivos desenvolvidos. Foram descritos e amostrados cinco perfis de solos em toposseqüência numa encosta de relevo suave ondulado. Características morfológicas, físicas e químicas foram estudadas tanto entre os horizontes do perfil, quanto entre os perfis ao longo do relevo. A variabilidade observada reflete as condições impostas pelo posicionamento dos solos na paisagem, sobretudo no que se refere às condições de infiltração de água e drenagem diferenciada

    Solos do Campo Experimental Pedro Arle em Frei Paulo - Sergipe.

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    A Embrapa Tabuleiros Costeiros vem desenvolvendo estudos comparativos de variedades e híbridos adaptados às condições semiáridas do Nordeste, selecionando os melhores para indicar seu cultivo e, assim, participar efetivamente do progresso da agricultura da Região. Estudar as características dos solos onde estes trabalhos estão sendo conduzidos é de fundamental importância para o planejamento de novas pesquisas, para a avaliação dos resultados obtidos e para que as informações possam ser extrapoladas para locais com condições edafoclimáticas semelhantes. O objetivo deste trabalho foi estudar os solos do Campo Experimental Pedro Arle, da Embrapa Tabuleiros Costeiros, localizado no município de Frei Paulo, em Sergipe. Para tanto, foi estudada uma topossequência em área onde vem sendo conduzidos experimentos com milho, obtendo-se altas produtividades. Vertissolo Háplico Órtico típico e Cambissolo Háplico Ta Eutrófico vertissólico foram encontrados na parte mais elevada da topossequência. Cambissolos Háplicos Ta Eutróficos, variando entre léptico e lítico, ocupam as posições de terço médio, inferior e a baixada. As análises refletem as limitações agrícolas destes solos relacionadas à sua profundidade efetiva e sua potencialidade que está diretamente relacionada à fertilidade natural

    Differences between <i>Trypanosoma brucei gambiense</i> groups 1 and 2 in their resistance to killing by Trypanolytic factor 1

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    &lt;p&gt;&lt;b&gt;Background:&lt;/b&gt; The three sub-species of &lt;i&gt;Trypanosoma brucei&lt;/i&gt; are important pathogens of sub-Saharan Africa. &lt;i&gt;T. b. brucei&lt;/i&gt; is unable to infect humans due to sensitivity to trypanosome lytic factors (TLF) 1 and 2 found in human serum. &lt;i&gt;T. b. rhodesiense&lt;/i&gt; and &lt;i&gt;T. b. gambiense&lt;/i&gt; are able to resist lysis by TLF. There are two distinct sub-groups of &lt;i&gt;T. b. gambiense&lt;/i&gt; that differ genetically and by human serum resistance phenotypes. Group 1 &lt;i&gt;T. b. gambiense&lt;/i&gt; have an invariant phenotype whereas group 2 show variable resistance. Previous data indicated that group 1 &lt;i&gt;T. b. gambiense&lt;/i&gt; are resistant to TLF-1 due in-part to reduced uptake of TLF-1 mediated by reduced expression of the TLF-1 receptor (the haptoglobin-hemoglobin receptor (&lt;i&gt;HpHbR&lt;/i&gt;)) gene. Here we investigate if this is also true in group 2 parasites.&lt;/p&gt; &lt;p&gt;&lt;b&gt;Methodology:&lt;/b&gt; Isogenic resistant and sensitive group 2 &lt;i&gt;T. b. gambiense&lt;/i&gt; were derived and compared to other T. brucei parasites. Both resistant and sensitive lines express the &lt;i&gt;HpHbR&lt;/i&gt; gene at similar levels and internalized fluorescently labeled TLF-1 similar fashion to &lt;i&gt;T. b. brucei&lt;/i&gt;. Both resistant and sensitive group 2, as well as group 1 &lt;i&gt;T. b. gambiense&lt;/i&gt;, internalize recombinant APOL1, but only sensitive group 2 parasites are lysed.&lt;/p&gt; &lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Our data indicate that, despite group 1 &lt;i&gt;T. b. gambiense&lt;/i&gt; avoiding TLF-1, it is resistant to the main lytic component, APOL1. Similarly group 2 &lt;i&gt;T. b. gambiense&lt;/i&gt; is innately resistant to APOL1, which could be based on the same mechanism. However, group 2 &lt;i&gt;T. b. gambiense&lt;/i&gt; variably displays this phenotype and expression does not appear to correlate with a change in expression site or expression of &lt;i&gt;HpHbR&lt;/i&gt;. Thus there are differences in the mechanism of human serum resistance between &lt;i&gt;T. b. gambiense&lt;/i&gt; groups 1 and 2.&lt;/p&gt

    Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza virus that expresses an altered nucleoprotein sequence

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    Influenza virus poses a difficult challenge for protective immunity. This virus is adept at altering its surface proteins, the proteins that are the targets of neutralizing antibody. Consequently, each year a new vaccine must be developed to combat the current recirculating strains. A universal influenza vaccine that primes specific memory cells that recognise conserved parts of the virus could prove to be effective against both annual influenza variants and newly emergent potentially pandemic strains. Such a vaccine will have to contain a safe and effective adjuvant that can be used in individuals of all ages. We examine protection from viral challenge in mice vaccinated with the nucleoprotein from the PR8 strain of influenza A, a protein that is highly conserved across viral subtypes. Vaccination with nucleoprotein delivered with a universally used and safe adjuvant, composed of insoluble aluminium salts, provides protection against viruses that either express the same or an altered version of nucleoprotein. This protection correlated with the presence of nucleoprotein specific CD8 T cells in the lungs of infected animals at early time points after infection. In contrast, immunization with NP delivered with alum and the detoxified LPS adjuvant, monophosphoryl lipid A, provided some protection to the homologous viral strain but no protection against infection by influenza expressing a variant nucleoprotein. Together, these data point towards a vaccine solution for all influenza A subtypes

    Prevalence of antibodies against caseous lymphadenitis in commercial sheep herds in the Federal District, Brazil

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    O objetivo deste trabalho foi determinar a prevalência de anticorpos contra linfadenite caseosa (LC) em rebanhos ovinos comerciais do Distrito Federal (DF). Foram coletadas 1.028 amostras de soro entre março e junho de 2004, de todas as propriedades (32) do Distrito Federal com pelo menos 20 fêmeas adultas no rebanho. A soroprevalência da linfadenite caseosa foi determinada por ELISA com proteínas secretadas de Corynebacterium pseudotuberculosis. Cinquenta por cento das 32 propriedades apresentaram pelo menos um animal soropositivo para o LC e a prevalência real para animais foi de 44,0% (IC 95: 41,0; 47,0), portanto, esses dados sugerem que a LC está presente em rebanhos ovinos comerciais no Distrito Federal.The objective of this study was to determinate the seroprevalence of caseous lymphadenitis (CL) in commercial sheep herds in the Federal District, Brazil. One thousand and twenty-eight serum samples were collected, between March and June 2004, from all the properties (32) with at least 20 adult females in the flock. The seroprevalence of caseous lymphadenitis was determined by ELISA with secreted proteins of Corynebacterium pseudotuberculosis. The real prevalence value for the animals was 44.0% (CI 95: 41.0; 47.0), and 50.0% of the 32 herds had at least one animal seropositive for CL. Therefore, these data show that CL is fairly widespread in commercial flocks of sheep in the Federal District

    The economic case for prioritizing governance over financial incentives in REDD+

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    This article contributes to the ongoing debate on the role of public policies and financial incentives in Reducing Emissions from Deforestation and forest Degradation (REDD+). It argues that the subordination of policies to results-based payments for emission reductions causes severe economic inefficiencies affecting the opportunity cost, transaction cost and economic rent of the programme. Such problems can be addressed by establishing sound procedural, land and financial governance at the national level, before REDD+ economic incentives are delivered at scale. Consideration is given to each governance dimension, the entry points for policy intervention and the impact on costs. International support must consider the financial and political cost of governance reforms, and use a pay-for-results ethos based on output and outcome indicators. This can be done in the readiness process but only if the latter’s legal force, scope, magnitude and time horizon are adequately reconsidered. In sum, the paper provides ammunition for the institutionalist argument that UNFCCC Parties must prioritise governance reform between now and the entry into force of the new climate agreement in 2020, and specific recommendations about how this can be done: only by doing so will they create the basis for the programme’s financial sustainability
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