72 research outputs found
Prosthetic joint infection caused by Pasteurella multocida: a case series and review of literature
- Author
- A Gupta
- AJ Griffin
- Andreas Stein
- AP Kadakia
- B Heym
- B Taillan
- BA Lipsky
- BD Braithwaite
- CL RomanĂČ
- CP Luessenhop
- D Tena
- DA Talan
- DW Orton
- E Gomez
- Estelle Honnorat
- Fabrice Simon
- GD Arvan
- GK Polzhofer
- GM Gabuzda
- H Mehta
- HĂ©lĂšne Savini
- J Chikwe
- J Ciampolini
- J Heydemann
- JA Maradona
- JB Stiehl
- JW Mellors
- KB Ferguson
- KH Maurer
- M Drancourt
- M Drancourt
- M Sugarman
- ME Olson
- Pierre-Olivier Pinelli
- Piseth Seng
- PJ Spagnuolo
- RD Griego
- S Vasoo
- SA Antuña
- TL Guion
- VJ Takwale
- W Zimmerli
- WT Hubbert
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Bridging the legitimacy gapâtranslating theory into practical signposts for legitimate flood risk governance
- Author
- A Berghofer
- A Buuren van
- A Gupta
- BA Cosens
- C Barnaud
- C Butler
- C Cheyne
- C Hendriks
- C Johnson
- C Suykens
- C Termeer
- D Miller
- DC Esty
- E SĂžrensen
- E-H Klijn
- EC Penning-Rowsell
- European Commission
- F Biermann
- F Scharpf
- F Spagnuolo
- FW Scharpf
- G Marks
- G Walker
- H Mees
- H Mees
- HFMW Rijswick Van
- HLP Mees
- J Alphen van
- J Chakraborty
- J Ebbesson
- J Johansson
- J Johansson
- J Paavola
- J Paavola
- J Pierre
- J Rawls
- JG March
- JL Fielding
- K Charmaz
- K Dombrowski
- K Kersbergen van
- KO Lindgren
- M Alexander
- M Cashmore
- M Fournier
- M Lockwood
- M Weber
- Meghan Alexander
- MR Mason
- N Doorn
- ND Gross-Camp
- Neelke Doorn
- NW Adger
- O Renn
- P Driessen
- PJ Driessen
- PPJ Driessen
- R Few
- RB Mitchell
- RL Lawrence
- S Bernstein
- S Birnbaum
- S Goytia
- Sally Priest
- SC Jagers
- SH Eriksen
- SJ Priest
- T Hartmann
- T Risse
- T Thaler
- T Thaler
- VA Schmidt
- WF Baber
- WJ Doorn-Hoekveld van
- Y Hirabayashi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Legitimacy is widely regarded as a founding principle of âgoodâ and effective governance, yet despite intense academic debate and policy discourse, the concept remains conceptually confusing and poorly articulated in practice. To bridge this gap, this research performed an interpretive thematic analysis of academic scholarship across public administration, public policy, law, political science and geography. Three core themes were identified in relation to representative deliberation, procedural and distributive equity and justice, and socio-political acceptability, with numerous sub-themes therein. In an attempt to clarify conceptual confusion, this paper grounds these theoretical debates in the context of flood risk governance where numerous legitimacy dilemmas exist. A number of questions are presented as conceptual âsign postsâ to encourage reflexive governance in the future. Thus, more broadly, we assert the importance of bringing legitimacy to the forefront of contemporary flood risk governance discourse and practice, moving beyond the realm of academic reflection
2-Hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation
- Author
- A Di Pietro
- A Eckhardt
- A Paranjpe
- A Takahashi
- AP Eker
- AR Collins
- B Tudek
- Cezary J. Chojnacki
- CH Camargo
- DA Ribeiro
- DM Yourtee
- DM Yourtee
- DY Xie
- E Norberg
- E Pawlowska
- E Urcan
- EC Munksgaard
- EL Kostoryz
- EL Kostoryz
- Elzbieta Pawlowska
- Ewelina Synowiec
- G Nocca
- G Spagnuolo
- GW Slater
- H Gao
- H Schweikl
- H Schweikl
- H Schweikl
- H Schweikl
- HE Krokan
- HH Chang
- I Ruyter
- IA Rodriguez
- IB Larsen
- J Blasiak
- J Cadet
- J Custodio
- J Durner
- J Zuo
- Jan Chojnacki
- Janusz Blasiak
- JG Park
- JG Park
- Joanna Szczepanska
- JP Santerre
- JP Szaflik
- JR Prensner
- JT Samuelsen
- K Rothkamm
- L Méndez-Acuña
- LJ Mah
- M Klaude
- M Koskinen
- M Nieborowska-Skorska
- M Seiss
- M Seiss
- MC Chang
- MM Vilenchik
- N Silikas
- NH Kleinsasser
- NP Singh
- NP Singh
- OA Sedelnikova
- PJ Koin
- PY Tong
- R Kainthla
- RR Tice
- T Helleday
- T Poplawski
- T Poplawski
- Tomasz Poplawski
- UI Walther
- VB Michelsen
- YJ Jung
- YK Lee
- Publication venue
- Springer Netherlands
- Publication date
- 01/01/2011
- Field of study
HEMA (2-hydroxyethyl methacrylate), a methacrylate commonly used in dentistry, was reported to induce genotoxic effects, but their mechanism is not fully understood. HEMA may be degraded by the oral cavity esterases or through mechanical stress following the chewing process. Methacrylic acid (MAA) is the primary product of HEMA degradation. In the present work we compared cytotoxic and genotoxic effects induced by HEMA and MAA in human gingival fibroblasts (HGFs). A 6-h exposure to HEMA or MAA induced a weak decrease in the viability of HGFs. Neither HEMA nor MAA induced strand breaks in the isolated plasmid DNA, but both compounds evoked DNA damage in HGFs, as evaluated by the alkaline comet assay. Oxidative modifications to the DNA bases were monitored by the DNA repair enzymes Endo III and Fpg. DNA damage induced by HEMA and MAA was not persistent and was removed during a 120Â min repair incubation. Results from the neutral comet assay indicated that both compounds induced DNA double strand breaks (DSBs) and they were confirmed by the Îł-H2AX assay. Both compounds induced apoptosis and perturbed the cell cycle. Therefore, methacrylic acid, a product of HEMA degradation, may be involved in its cytotoxic and genotoxic action
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-GĂłmez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- AntĂłn Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- AraĂșjo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- BarilĂ D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
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- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
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- Begun J
- Behl C
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- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Search for gravitational waves associated with gamma-ray bursts detected by Fermi and Swift during the LIGOâVirgo run O3b
- Author
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- Ying M
- Yokogawa K
- Yokoyama J
- Yokozawa T
- Yoo J
- Yoshioka T
- Yu H
- Yu H
- Yuzurihara H
- Zadrozny A
- Zanolin M
- Zeidler S
- Zelenova T
- Zendri J-P
- Zevin M
- Zhan M
- Zhang H
- Zhang J
- Zhang L
- Zhang T
- Zhang Y
- Zhao C
- Zhao G
- Zhao Y
- Zhao Y
- Zheng Y
- Zhou R
- Zhou Z
- Zhu XJ
- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2022
- Field of study
We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTCâ2020 March 27 17:00 UTC). We conduct two independent searches: a generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate
Advanced Pelvic Actinomycosis with Ureteric Obstruction and Involvement of the Iliopsoas Musculature
- Publication venue
- 'Mary Ann Liebert Inc'
- Publication date
- Field of study
IUD-associated ovarian actinomycosis causing bowel obstruction
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Liberation of vasoactive substances and its prevention with thromboxane A 2
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Immunosuppressive drugs and their effect on experimental tumor growth
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Antithrombotic effects of S 18886, a novel orally active thromboxane A2 receptor antagonist
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
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