1,720 research outputs found

    Invariant NKT cells and rheumatic disease: Focus on primary sjogren syndrome

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    Primary Sjogren syndrome (pSS) is a complex autoimmune disease mainly affecting salivary and lacrimal glands. Several factors contribute to pSS pathogenesis; in particular, innate immunity seems to play a key role in disease etiology. Invariant natural killer (NK) T cells (iNKT) are a T-cell subset able to recognize glycolipid antigens. Their function remains unclear, but studies have pointed out their ability to modulate the immune system through the promotion of specific cytokine milieu. In this review, we discussed the possible role of iNKT in pSS development, as well as their implications as future markers of disease activity

    New radio halos and relics in clusters of galaxies

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    We present here new images of relics and halo sources in rich cluster of galaxies and the correlation between the halo radio surface brightness versus the cluster bolometric X-ray luminosity.Comment: 2 pages, 4 figures. To appear in the Proceedings of the International Conference: "The Origin and Evolution of Cosmic Magnetism"; Bologna 29 August - 2 September 2005; eds R. Beck, G. Brunetti, L. Feretti, and B. Gaensler (Astronomische Nachrichten, 2006

    Transmission electron microscopy characterization of microstructural features of Al-Li-Cu alloys

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    A transmission electron microscopy (TEM) examination of aluminum-lithium-copper alloys was conducted. The principal purpose is to characterize the nature, size, and distribution of stringer particles which result from the powder metallurgy (P/M) processing of these alloys. Microstructural features associated with the stringer particles are reported that help explain the stress corrosion susceptibility of the powder metallurgy-processed Al-Li-Cu alloys. In addition, matrix precipitation events are documented for a variety of heat treatments and process variations. Hot rolling is observed to significant alter the nature of matrix precipitation, and the observations are correlated with concomitant mechanical property variations

    Stream dynamics between 1 AU and 2 AU: A detailed comparison of observations and theory

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    A radial alignment of three solar wind stream structures observed by IMP-7 and -8 (at 1.0 AU) and Voyager 1 and 2 (in the range 1.4 to 1.8 AU) in late 1977 is presented. It is demonstrated that several important aspects of the observed dynamical evolution can be both qualitatively and quantitatively described with a single-fluid 2-D MHD numerical model of quasi-steady corotating flow, including accurate prediction of: (1) the formation of a corotating shock pair at 1.75 AU in the case of a simple, quasi-steady stream; (2) the coalescence of the thermodynamic and magnetic structures associated with the compression regions of two neighboring, interacting, corotating streams; and (3) the dynamical destruction of a small (i.e., low velocity-amplitude, short spatial-scale) stream by its overtaking of a slower moving, high-density region associated with a preceding transient flow. The evolution of these flow systems is discussed in terms of the concepts of filtering and entrainment

    Spatially-Stationary Model for Holographic MIMO Small-Scale Fading

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    Imagine an array with a massive (possibly uncountably infinite) number of antennas in a compact space. We refer to a system of this sort as Holographic MIMO. Given the impressive properties of Massive MIMO, one might expect a holographic array to realize extreme spatial resolution, incredible energy efficiency, and unprecedented spectral efficiency. At present, however, its fundamental limits have not been conclusively established. A major challenge for the analysis and understanding of such a paradigm shift is the lack of mathematically tractable and numerically reproducible channel models that retain some semblance to the physical reality. Detailed physical models are, in general, too complex for tractable analysis. This paper aims to take a closer look at this interdisciplinary challenge. Particularly, we consider the small-scale fading in the far-field, and we model it as a zero-mean, spatially-stationary, and correlated Gaussian scalar random field. A physically-meaningful correlation is obtained by requiring that the random field be consistent with the scalar Helmholtz equation. This formulation leads directly to a rather simple and exact description of the three-dimensional small-scale fading as a Fourier plane-wave spectral representation. Suitably discretized, this yields a discrete representation for the field as a Fourier plane-wave series expansion, from which a computationally efficient way to generate samples of the small-scale fading over spatially-constrained compact spaces is developed. The connections with the conventional tools of linear systems theory and Fourier transform are thoroughly discussed

    Degrees of Freedom of Holographic MIMO Channels

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    We consider spatially-constrained apertures of rectangular symmetry and aim to retrieve the limit to the average number of channel spatial degrees of freedom (DoF), obtained elsewhere through different analyses and tools. Unlike prior works, we use a novel Fourier plane-wave series expansion of the channel, recently introduced in [1], where a statistical model for the small-scale fading in the far-field is developed on the basis of a continuous-space and physics-based orthonormal expansion over the Cartesian spatial Fourier basis. This expansion yields a set of statistically independent random coefficients whose cardinality directly gives the limit to the average number of DoF. The treatment is limited to an isotropic scattering environment but can be extended to the non-isotropic case through the linear-system theoretic interpretation of plane-wave propagation

    Absence of Embedded Mass Shells: Cerenkov Radiation and Quantum Friction

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    We show that, in a model where a non-relativistic particle is coupled to a quantized relativistic scalar Bose field, the embedded mass shell of the particle dissolves in the continuum when the interaction is turned on, provided the coupling constant is sufficiently small. More precisely, under the assumption that the fiber eigenvectors corresponding to the putative mass shell are differentiable as functions of the total momentum of the system, we show that a mass shell could exist only at a strictly positive distance from the unperturbed embedded mass shell near the boundary of the energy-momentum spectrum.Comment: Revised version: a remark added at the end of Section

    The Sunyaev-Zeldovich Effect at 1 and 2 mm towards ROSAT Clusters

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    An observing campaign was devoted to the search for the Sunyaev-Zeldovich (S-Z) effect towards X-ray ROSAT Clusters in the millimetric spectral domain. A double channel (1.2 and 2 {\it mm}) photometer was installed at the focus of the 15m Swedish ESO Submillimeter Telescope (SEST) in Chile in september 1994 and 1995 and observations of the targets S1077, A2744, S295 and RXJ0658-5557 were gathered. Detections were found for A2744 at 1 {\it mm} and in both channels (at 1.2 and 2 {\it mm}) towards RXJ0658-5557. For the first time there is evidence for the S-Z enhancement and both the latter and the decrement were detected on the same source. We discuss astrophysical and systematic effects which could give origin to these signals.Comment: 6 pg Latex file (style file included) including 1 ps figure, XVIth Moriond Astrophysics Meeting "The Anisotropies of the Cosmic Microwave Background", Les Arcs, Savoie-France, March 16-23 199

    Challenges in Dental Statistics: Survey Methodology Topics

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    This paper gathers some contributions concerning survey methodology in dental research, as discussed during the first Workshop of the SISMEC STATDENT working group on statistical methods and applications in dentistry, held in Ancona on the 28th September 2011. The first contribution deals with the European Global Oral Health Indicators Development (EGOHID) Project which proposed a comprehensive and standardized system of epidemiological tools (questionnaires and clinical forms) for national data collection on oral health in Europe. The second contribution regards the design and conduct of trials to evaluate the clinical efficacy and safety of toothbrushes and mouthrinses. Finally, a flexible and effective tool used to trace dental age reference charts tailored to Italian children was presented
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