4,619 research outputs found

    Sensitivity-based scaling for correlating structural response from different analytical models

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    A sensitivity-based linearly varying scale factor is described used to reconcile results from refined models for analysis of the same structure. The improved accuracy of the linear scale factor compared to a constant scale factor as well as the commonly used tangent approximation is demonstrated. A wing box structure is used as an example, with displacements, stresses, and frequencies correlated. The linear scale factor could permit the use of a simplified model in an optimization procedure during preliminary design to approximate the response given by a refined model over a considerable range of design changes

    Deep Interest Evolution Network for Click-Through Rate Prediction

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    Click-through rate~(CTR) prediction, whose goal is to estimate the probability of the user clicks, has become one of the core tasks in advertising systems. For CTR prediction model, it is necessary to capture the latent user interest behind the user behavior data. Besides, considering the changing of the external environment and the internal cognition, user interest evolves over time dynamically. There are several CTR prediction methods for interest modeling, while most of them regard the representation of behavior as the interest directly, and lack specially modeling for latent interest behind the concrete behavior. Moreover, few work consider the changing trend of interest. In this paper, we propose a novel model, named Deep Interest Evolution Network~(DIEN), for CTR prediction. Specifically, we design interest extractor layer to capture temporal interests from history behavior sequence. At this layer, we introduce an auxiliary loss to supervise interest extracting at each step. As user interests are diverse, especially in the e-commerce system, we propose interest evolving layer to capture interest evolving process that is relative to the target item. At interest evolving layer, attention mechanism is embedded into the sequential structure novelly, and the effects of relative interests are strengthened during interest evolution. In the experiments on both public and industrial datasets, DIEN significantly outperforms the state-of-the-art solutions. Notably, DIEN has been deployed in the display advertisement system of Taobao, and obtained 20.7\% improvement on CTR.Comment: 9 pages. Accepted by AAAI 201

    Irrational vs. rational charge and statistics in two-dimensional quantum systems

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    We show that quasiparticle excitations with irrational charge and irrational exchange statistics exist in tight-biding systems described, in the continuum approximation, by the Dirac equation in (2+1)-dimensional space and time. These excitations can be deconfined at zero temperature, but when they are, the charge re-rationalizes to the value 1/2 and the exchange statistics to that of "quartons" (half-semions).Comment: 4 pages, 2 figure

    Ontology-based Fuzzy Markup Language Agent for Student and Robot Co-Learning

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    An intelligent robot agent based on domain ontology, machine learning mechanism, and Fuzzy Markup Language (FML) for students and robot co-learning is presented in this paper. The machine-human co-learning model is established to help various students learn the mathematical concepts based on their learning ability and performance. Meanwhile, the robot acts as a teacher's assistant to co-learn with children in the class. The FML-based knowledge base and rule base are embedded in the robot so that the teachers can get feedback from the robot on whether students make progress or not. Next, we inferred students' learning performance based on learning content's difficulty and students' ability, concentration level, as well as teamwork sprit in the class. Experimental results show that learning with the robot is helpful for disadvantaged and below-basic children. Moreover, the accuracy of the intelligent FML-based agent for student learning is increased after machine learning mechanism.Comment: This paper is submitted to IEEE WCCI 2018 Conference for revie

    Driven Graphene as a Tunable Semiconductor with Topological Properties

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    Controlling the properties of materials by driving them out of equilibrium is an exciting prospect that has only recently begun to be explored. In this Letter we give a striking theoretical example of such materials design: a tunable gap in monolayer graphene is generated by exciting a particular optical phonon. We show that the system reaches a steady state whose transport properties are the same as if the system had a static electronic gap, controllable by the driving amplitude. Moreover, the steady state displays topological phenomena: there are chiral edge currents, which circulate a fractional charge e/2 per rotation cycle, with the frequency set by the optical phonon frequency

    Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: An Arg‐Gly‐Asp‐dependent‐focal adhesion kinase‐caspase‐8 axis

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    Osteopontin (OPN), an adhesive, matricellular glycoprotein, is a rate‐limiting factor in tumor promotion of skin carcinogenesis. With a tumor promotion model, the JB6 Cl41.5a cell line, we have shown that suppressing 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA)‐induced OPN expression markedly inhibits TPA‐induced colony formation in soft agar, an assay indicative of tumorigenic transformation. Further, the addition of exogenous OPN promotes colony formation of these cells. These findings support a function of OPN in mediating TPA‐induced neoplastic transformation of JB6 cells. In regard to the mechanism of action by OPN, we hypothesized that, for JB6 cells grown in soft‐agar, secreted OPN induced by TPA stimulates cell proliferation and/or prevents anoikis to facilitate TPA‐induced colony formation. Analyses of cell cycle and cyclin D1 expression, and direct cell counting of JB6 cells treated with OPN indicate that OPN does not stimulate cell proliferation relative to non‐treated controls. Instead, at 24 h, OPN decreases anoikis by 41%, as assessed by annexin V assays. Further, in suspended cells OPN suppresses caspase‐8 activation, which is mediated specifically through its RGD‐cell binding motif that transduces signals through integrin receptors. Transfection studies with wild‐type and mutant focal adhesion kinases (FAK) and Western blot analyses suggest that OPN suppression of caspase‐8 activation is mediated through phosphorylation of FAK at Tyr861. In summary, these studies indicate that induced OPN is a microenvironment modulator that facilitates tumorigenic transformation of JB6 cells by inhibiting anoikis through its RGD‐dependent suppression of caspase‐8 activity, which is mediated in part through the activation of FAK at Tyr861. © 2013 Wiley Periodicals, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111135/1/mc22108.pd
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