The Growth of Black Holes and Bulges at the Cores of Cooling Flows

Central cluster galaxies (cDs) in cooling flows are growing rapidly through gas accretion and star formation. At the same time, AGN outbursts fueled by accretion onto supermassive black holes are generating X-ray cavity systems and driving outflows that exceed those in powerful quasars. We show that the resulting bulge and black hole growth follows a trend that is roughly consistent with the slope of the local (Magorrian) relation between bulge and black hole mass for nearby quiescent ellipticals. However, a large scatter suggests that cD bulges and black holes do not always grow in lock-step. New measurements made with XMM, Chandra, and FUSE of the condensation rates in cooling flows are now approaching or are comparable to the star formation rates, alleviating the need for an invisible sink of cold matter. We show that the remaining radiation losses can be offset by AGN outbursts in more than half of the systems in our sample, indicating that the level of cooling and star formation is regulated by AGN feedback.Comment: 3 pages, 4 figures, to appear in the proceedings of "Heating vs. Cooling in Galaxies and Clusters of Galaxies," edited by H. Boehringer, P. Schuecker, G. W. Pratt, and A. Finogueno

The temperature structure in the core of Sersic 159-03

We present results from a new 120 ks XMM-Newton observation of the cluster of galaxies Sersic 159-03. In this paper we focus on the high-resolution X-ray spectra obtained with the Reflection Grating Spectrometer (RGS). The spectra allow us to constrain the temperature structure in the core of the cluster and determine the emission measure distribution as a function of temperature. We also fit the line widths of mainly oxygen and iron lines.Comment: 7 pages and 4 figures. Contribution to the proceedings of the COSPAR Scientific Assembly, session E1.2 "Clusters of Galaxies: New Insights from XMM-Newton, Chandra and INTEGRAL", july 2004, Paris (France). Accepted for publication in Advances in Space Researc

Tracing Ghost Cavities with Low Frequency Radio Observations

We present X-ray and multi-frequency radio observations of the central radio sources in several X-ray cavity systems. We show that targeted radio observations are key to determining if the lobes are being actively fed by the central AGN. Low frequency observations provide a unique way to study both the lifecycle of the central radio source as well as its energy input into the ICM over several outburst episodes.Comment: 6 pages, 4 figures, To appear in the Proceedings of "Heating vs. Cooling in Galaxies and Clusters of Galaxies", eds. H. Boehringer, P. Schuecker, G. W. Pratt & A. Finoguenov (ESO Astrophysics Symposia, Springer-Verlag), Garching (Germany), August 200

Enhanced Fusion-Evaporation Cross Sections in Neutron-Rich 132^{132}Sn on 64^{64}Ni

Evaporation residue cross sections have been measured with neutron-rich radioactive $^{132}$Sn beams on $^{64}$Ni in the vicinity of the Coulomb barrier. The average beam intensity was $2\times 10^{4}$ particles per second and the smallest cross section measured was less than 5 mb. Large subbarrier fusion enhancement was observed. Coupled-channels calculations taking into account inelastic excitation and neutron transfer underpredict the measured cross sections below the barrier.Comment: 4 pages including 1 table and 3 figure

The Two Dimensional Kondo Model with Rashba Spin-Orbit Coupling

We investigate the effect that Rashba spin-orbit coupling has on the low energy behaviour of a two dimensional magnetic impurity system. It is shown that the Kondo effect, the screening of the magnetic impurity at temperatures T < T_K, is robust against such spin-orbit coupling, despite the fact that the spin of the conduction electrons is no longer a conserved quantity. A proposal is made for how the spin-orbit coupling may change the value of the Kondo temperature T_K in such systems and the prospects of measuring this change are discussed. We conclude that many of the assumptions made in our analysis invalidate our results as applied to recent experiments in semi-conductor quantum dots but may apply to measurements made with magnetic atoms placed on metallic surfaces.Comment: 22 pages, 1 figure; reference update

Cold Feedback in Cooling-Flow Galaxy Clusters

We put forward an alternative view to the Bondi-driven feedback between heating and cooling of the intra-cluster medium (ICM) in cooling flow galaxies and clusters. We adopt the popular view that the heating is due to an active galactic nucleus (AGN), i.e. a central black hole accreting mass and launching jets and/or winds. We propose that the feedback occurs with the entire cool inner region (5-30 kpc). A moderate cooling flow does exist here, and non-linear over-dense blobs of gas cool fast and are removed from the ICM before experiencing the next major AGN heating event. Some of these blobs may not accrete on the central black hole, but may form stars and cold molecular clouds. We discuss the conditions under which the dense blobs may cool to low temperatures and feed the black hole.Comment: 6 pages, no figures, to appear in the Proceedings of "Heating vs. Cooling in Galaxies and Clusters of Galaxies", August 2006, Garching (Germany

Active Galaxies in the UV

In this article we present different aspects of AGN studies demonstrating the importance of the UV spectral range. Most important diagnostic lines for studying the general physical conditions as well as the metalicities in the central broad line region in AGN are emitted in the UV. The UV/FUV continuum in AGN excites not only the emission lines in the immediate surrounding but it is responsible for the ionization of the intergalactic medium in the early stages of the universe. Variability studies of the emission line profiles of AGN in the UV give us information on the structure and kinematics of the immediate surrounding of the central supermassive black hole as well as on its mass itself.Comment: 29 pages, 13 figures, Ap&SS in pres

An oncogenic role for sphingosine kinase 2

While both human sphingosine kinases (SK1 and SK2) catalyze the generation of the pleiotropic signaling lipid sphingosine 1-phosphate, these enzymes appear to be functionally distinct. SK1 has well described roles in promoting cell survival, proliferation and neoplastic transformation. The roles of SK2, and its contribution to cancer, however, are much less clear. Some studies have suggested an antiproliferative/ pro-apoptotic function for SK2, while others indicate it has a prosurvival role and its inhibition can have anti-cancer effects. Our analysis of gene expression data revealed that SK2 is upregulated in many human cancers, but only to a small extent (up to 2.5-fold over normal tissue). Based on these findings, we examined the effect of different levels of cellular SK2 and showed that high-level overexpression reduced cell proliferation and survival, and increased cellular ceramide levels. In contrast, however, low-level SK2 overexpression promoted cell survival and proliferation, and induced neoplastic transformation in vivo. These findings coincided with decreased nuclear localization and increased plasma membrane localization of SK2, as well as increases in extracellular S1P formation. Hence, we have shown for the first time that SK2 can have a direct role in promoting oncogenesis, supporting the use of SK2-specific inhibitors as anti-cancer agents.Heidi A. Neubauer, Duyen H. Pham, Julia R. Zebol, Paul A.B. Moretti, Amanda L. Peterson, Tamara M. Leclercq, Huasheng Chan, Jason A. Powell, Melissa R. Pitman, Michael S. Samuel, Claudine S. Bonder, Darren J. Creek, Briony L. Gliddon and Stuart M. Pitso