2,005 research outputs found
Optogenetic manipulation of stomatal kinetics improves carbon assimilation, water use, and growth
Stomata serve dual and often conflicting roles, facilitating carbon dioxide influx into the plant leaf for photosynthesis and restricting water efflux via transpiration. Strategies for reducing transpiration without incurring a cost for photosynthesis must circumvent this inherent coupling of carbon dioxide and water vapor diffusion. We expressed the synthetic, light-gated K+ channel BLINK1 in guard cells surrounding stomatal pores in Arabidopsis to enhance the solute fluxes that drive stomatal aperture. BLINK1 introduced a K+ conductance and accelerated both stomatal opening under light exposure and closing after irradiation. Integrated over the growth period, BLINK1 drove a 2.2-fold increase in biomass in fluctuating light without cost in water use by the plant. Thus, we demonstrate the potential of enhancing stomatal kinetics to improve water use efficiency without penalty in carbon fixation
Trends in sexually transmitted infections in general practice 1990-2000: population based study using data from the UK general practice research database
Objective: To describe the contribution of primary care to the
diagnosis and management of sexually transmitted infections in
the United Kingdom, 1990-2000, in the context of increasing
incidence of infections in genitourinary medicine clinics.
Design: Population based study.
Setting: UK primary care.
Participants: Patients registered in the UK general practice
research database.
Main outcome measures: Incidence of diagnosed sexually
transmitted infections in primary care and estimation of the
proportion of major such infections diagnosed in primary care.
Results: An estimated 23.0% of chlamydia cases in women but
only 5.3% in men were diagnosed and treated in primary care
during 1998-2000, along with 49.2% cases of non-specific
urethritis and urethral discharge in men and 5.7% cases of
gonorrhoea in women and 2.9% in men. Rates of diagnosis in
primary care rose substantially in the late 1990s.
Conclusions: A substantial and increasing number of sexually
transmitted infections are diagnosed and treated in primary
care in the United Kingdom, with sex ratios differing from
those in genitourinary medicine clinics. Large numbers of men
are treated in primary care for presumptive sexually
transmitted infections
Structure constants for the osp(1|2) current algebra
We study the free field realization of the two-dimensional osp(1|2) current
algebra. We consider the case in which the level of the affine osp(1|2)
symmetry is a positive integer. Using the Coulomb gas technique we obtain
integral representations for the conformal blocks of the model. In particular,
from the behaviour of the four-point function, we extract the structure
constants for the product of two arbitrary primary operators of the theory.
From this result we derive the fusion rules of the osp(1|2) conformal field
theory and we explore the connections between the osp(1|2) affine symmetry and
the N=1 superconformal field theories.Comment: 64 pages, phyzzx, no figure
Nested interactions between chemosynthetic lucinid bivalves and seagrass promote ecosystem functioning in contaminated sediments
In seagrass sediments, lucinid bivalves and their chemoautotrophic bacterial symbionts consume H2S, relying indirectly on the plant productivity for the presence of the reduced chemical. Additionally, the role of lucinid bivalves in N provisioning to the plant (through N2 fixation by the symbionts) was hypothesized. Thus, lucinids may contribute to sediment detoxification and plant fitness. Seagrasses are subject to ever-increasing human pressure in coastal environments. Here, disentangling nested interactions between chemosynthetic lucinid bivalves and seagrass exposed to pollution may help to understand seagrass ecosystem dynamics and to develop successful seagrass restoration programs that consider the roles of animal-microbe symbioses. We evaluated the capacity of lucinid bivalves (Loripes orbiculatus) to promote nutrient cycling and seagrass (Cymodocea nodosa) growth during a 6-week mesocosm experiment. A fully crossed design was used to test for the effect of sediment contamination (metals, nutrients, and hydrocarbons) on plant and bivalve (alone or interacting) fitness, assessed by mortality, growth, and photosynthetic efficiency, and for the effect of their nested interaction on sediment biogeochemistry. Plants performed better in the contaminated sediment, where a larger pool of dissolved nitrogen combined with the presence of other trace elements allowed for an improved photosynthetic efficiency. In fact, pore water nitrogen accumulated during the experiment in the controls, while it was consumed in the contaminated sediment. This trend was accentuated when lucinids were present. Concurrently, the interaction between clams and plants benefitted both organisms and promoted plant growth irrespective of the sediment type. In particular, the interaction with lucinid clams resulted in higher aboveground biomass of C. nodosa in terms of leaf growth, leaf surface, and leaf biomass. Our results consolidate the notion that nested interactions involving animal-microbe associations promote ecosystem functioning, and potentially help designing unconventional seagrass restoration strategies that exploit chemosynthetic symbioses.Versión del edito
Semiparametric theory and empirical processes in causal inference
In this paper we review important aspects of semiparametric theory and
empirical processes that arise in causal inference problems. We begin with a
brief introduction to the general problem of causal inference, and go on to
discuss estimation and inference for causal effects under semiparametric
models, which allow parts of the data-generating process to be unrestricted if
they are not of particular interest (i.e., nuisance functions). These models
are very useful in causal problems because the outcome process is often complex
and difficult to model, and there may only be information available about the
treatment process (at best). Semiparametric theory gives a framework for
benchmarking efficiency and constructing estimators in such settings. In the
second part of the paper we discuss empirical process theory, which provides
powerful tools for understanding the asymptotic behavior of semiparametric
estimators that depend on flexible nonparametric estimators of nuisance
functions. These tools are crucial for incorporating machine learning and other
modern methods into causal inference analyses. We conclude by examining related
extensions and future directions for work in semiparametric causal inference
Sagittal abdominal diameter: no advantage compared with other anthropometric measures as a correlate of components of the metabolic syndrome in elderly from the Hoorn Study.
BACKGROUND: The sagittal abdominal diameter has been proposed as a useful measure by which to estimate abdominal obesity and as being more strongly related to components of the metabolic syndrome than are other anthropometric measures. OBJECTIVE: The objective was to study which anthropometric measure (ie, sagittal abdominal diameter, waist circumference, waist-to-hip ratio, waist-to-height ratio, or body mass index) is the strongest correlate of components of the metabolic syndrome (ie, glucose and lipid concentrations and blood pressure) in the elderly. DESIGN: The Hoorn Study is a population-based cohort study in older Dutch men and women. Cross-sectional data were analyzed. Age-adjusted Pearson correlations of anthropometric measures with components of the metabolic syndrome were calculated in 826 subjects (389 men, 437 women) aged 56-83 y. Analyses were performed with adjustment for age and stratification for sex and age (/=65 y). RESULTS: No single anthropometric measure was consistently correlated more strongly with components of the metabolic syndrome than were the other measures in either men or women. The associations were generally stronger in younger subjects than in older subjects and in women than in men. For example, the correlation between sagittal abdominal diameter and postload glucose was 0.35 (P < 0.001) in younger and 0.14 (P = 0.051) in older men, and the correlation between waist circumference and postload glucose was 0.33 (P < 0.001) in older women and 0.14 (P = 0.062) in older men. CONCLUSION: The use of sagittal abdominal diameter has no advantages over simpler and more commonly used anthropometric measures such as the waist circumference in older men and women
Anti-de Sitter boundary in Poincare coordinates
We study the space-time boundary of a Poincare patch of Anti-de Sitter (AdS)
space. We map the Poincare AdS boundary to the global coordinate chart and show
why this boundary is not equivalent to the global AdS boundary. The Poincare
AdS boundary is shown to contain points of the bulk of the entire AdS space.
The Euclidean AdS space is also discussed. In this case one can define a
semi-global chart that divides the AdS space in the same way as the
corresponding Euclidean Poincare chart.Comment: In this revised version we add a discussion of the physical
consequences of the choice of a coordinate system for AdS space. We changed
figure 1 and added more references. Version to be published in Gen. Relat.
Grav
Meaningful engagement: computer-based interactive media art in public space.
Interactive technologies, including electronic devices are increasingly being utilized as a medium for artistic expression and have been placed in freely accessible public environments with mixed results. When audiences encounter computer-based interactive media arts in a public space they are drawn by various interactivities, to play and experiment with them. However, whether the audience is able to gain a meaningful experience through those physical interactivities has remained an issue of both theoretical and practical debate. This paper will focus on these aspects, most specifically through the study of interactive art in freely accessible public space. The author proposes four new conceptual/analytical tools for examining the subject. It is anticipated that this paper will provide possible alternative strategies for both artists and art researchers in this field with a purpose to enhance intellectual engagement with their audiences, so as to succeed in leading interactors to obtain meaningful experience and rewards
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