Two-axis flux gate magnetometer

Magnetometer uses single sensing head to measure magnetic flux density along two axes simultaneously. The sensor head consists of permalloy core and four windings. Two windings perform a multivibrator function, the two remaining windings sense magnetic fields. The smaller magnetometer performs same functions as more complex devices

Cosmic ray positron and negatron spectra between 20 and 800 MeV measured in 1974

A balloon-borne spark chamber magnetic spectrometer was used to measure separate spectra of positrons and negatrons in two flights during summer, 1974. The total electron flux is about 0.3 m(-2) s(-1) sr(-1) MeV(-1) between 70 and 800 MeV, and increases toward lower energies. The positron spectrum decreases sharply toward lower energies from a value of about 0.08 m(-2) s(-1) sr(-1) MeV(-1) at 650 MeV, and only upper limits are obtained for positrons below 200 MeV. At energies above 180 MeV, the spherically symmetric Fokker-Planck equation provides reasonable fits to both the positron and total electron data. At energies below 180 MeV the data are consistent with a continuation of the same diffusion coefficient and local source of negatrons, or a change in the diffusion coefficient to a constant value

Stellar Populations in Barred Galaxies

We developed an iterative technique to better characterize stellar populations and the central activity of barred galaxies using evolutionary synthesis codes and OASIS data. The case of NGC5430 is presented here. Our results are reinforcing the role played by the bar and nuclear structures for the evolution of galaxies.Comment: 2 pages, 1 figure, to be published in the proceedings of IAU Symp. 262 "Stellar Populations - Planing for the Next Decate" (Aug. 2009

Heavy solar cosmic rays in the January 25, 1971 solar flares

A detailed study of the charge composition of heavy solar cosmic rays measured in the January 25, 1971 solar flare including differential fluxes for the even charged nuclei from carbon through argon is presented. The measurements are obtained for varying energy intervals for each nuclear species in the energy range from 10 to 35 MeV/nucleon. In addition, abundances relative to oxygen are computed for all the above nuclei in the single energy interval from 15 to 25 MeV/nucleon. This interval contains measurements for all of the species and as a result requires no spectral extrapolations. An upper limit for the abundance of calcium nuclei is also presented. These measurements, when combined with other experimental results, enable the energy dependence of abundance measurements as a function of nuclear charge to be discussed. It is seen that at energies above about 10 MeV/nucleon, the variations of abundance ratios are limited to about a factor of 3 from flare to flare, in spite of large variations in other characteristics of these solar events

Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease.

Huntington's disease (HD) is a fatal neurodegenerative disease in which an early and selective vulnerability of striatal Spiny Projection Neurons is observed. However, several studies have highlighted the implication of glial cells, and in particular astrocytes, in the pathophysiological mechanisms of this disease. A better understanding of the respective contributions of neurons and astrocytes in HD is needed and would be important for the development of new therapeutic approaches. Today, no comparable in vivo models expressing the mutant HTT selectively in astrocytes or in neurons are available. In this study, we developed comparable cell-type specific mouse models expressing a fragment of Huntingtin specifically in neurons, astrocytes, or in both cell populations of the adult mouse basal ganglia circuit. This approach allowed us to characterize behavioral alterations occurring as soon as 4 weeks postinjection. Interestingly, less severe but significant behavioral alterations were also observed in the two cell-type specific models. We further showed that astrocytes are less affected by mHTT compared to neurons, in particular concerning mHTT aggregation. Additionally, a more indirect contribution of astrocytes compared to neurons was observed in several pathophysiological mechanisms such as astrogliosis and neuronal dysfunction. Finally, we showed that direct and indirect transcriptional alterations within the glial glutamatergic clearing system are caused by astrocytic and neuronal expression of mHTT, respectively. We anticipate that our study will help to better understand the contributions of astrocytes to HD and guide future therapeutic efforts. GLIA 2016;64:1841-1856

Structure and dynamics of Oxide Melts and Glasses : a view from multinuclear and high temperature NMR

Solid State Nuclear Magnetic Resonance (NMR) experiments allow characterizing the local structure and dynamics of oxide glasses and melts. Thanks to the development of new experiments, it now becomes possible to evidence not only the details of the coordination state of the network formers of glasses but also to characterize the nature of polyatomic molecular motifs extending over several chemical bonds. We present results involving 31P homonuclear experiments that allow description of groups of up to three phosphate units and 27Al/17O heteronuclear that allows evidencing μ3 oxygen bridges in aluminate glasses and rediscussion of the structure of high temperature melts.Comment: Journal of Non-Crystalline Solids (2007) in press; Also available online at: http://crmht.cnrs-orleans.fr/Intranet/Publications/?id=207