A new method for quantification of hepatobiliary scintigraphy using 99mTc-mebrofenin. A comparative study

A method based upon the application of mathematical techniques of deconvolution on the classical compartmental model for the quantitative study of liver function from hepatobiliary scintigraphy using 99mTc-mebrofenin data is proposed. The theory in which the method is based upon is presented and a comparison with a published methodology of obtaining the hepatic extraction after scintigraphic sudies has been performed using the results on 36 rats studies obtained with the two methods. A highly significant correlation between the two techniques was verified. The characteristics of the two methodologies, the proposed one based upon a theoretical approach and the other one on an empirical approximation are discussed. Comments are made on the interest and limitations of the presented technique that may be an useful tool for the evaluation of hepatic insufficiency

Silagem de cana-de-açúcar.

A cultura da cana-de-açúcar é intensamente difundida no Brasil. Programas como o Proálcool foram seus grandes incentivadores, expandindo o cultivo a extensas áreas, em regiões tradicionais de pecuária e produção de grãos, promovendo grande avanço nas técnicas de produção e lançamento de variedades com alto potencial de produção de biomassa e açúcar. A alta produtividade de massa verde (80 a 120 t/ha), o baixo custo por unidade de matéria seca (MS), a manutenção do valor nutritivo até seis meses após a maturação e o período de colheita coincidente com o período de escassez de forragem nas pastagens (SILVA, 1993), aliados à facilidade de obtenção de mudas e plantio, e a pos3ibilidade de atingir-se taxas de ganhos de peso razoáveis, têm atraído pécuaristas ao uso da cana-de açúcar como fonte de alimento volumoso na engorda de bovinos

Preimplantation biopsy predicts delayed graft function, glomerular filtration rate and long-term graft survival of transplanted kidneys

Background The predictive value of preimplantation biopsies for long-term graft function is often limited by conflicting results. The aim of this study was to evaluate the influence of time-zero graft biopsy histological scores on early and late graft function, graft survival and patient survival, at different time points. Methods We retrospectively analyzed 284 preimplantation biopsies at a single center, in a cohort of recipients with grafts from live and deceased donors (standard and nonstandard), and their impact in posttransplant renal function after a mean follow-up of 7 years (range 1–16). Implantation biopsy score (IBS), a combination score derived from 4 histopathological aspects, was determined from each sample. The correlation with incidence of delayed graft function (DGF), creatinine clearance (1st, 3rd and 5th posttransplant year) and graft and patient survival at 1 and 5 years were evaluated. Results Preimplantation biopsies provided somewhat of a prognostic index of early function and outcome of the transplanted kidney in the short and long term. In the immediate posttransplantation period, the degree of arteriolosclerosis and interstitial fibrosis correlated better with the presence of DGF. IBS values between 4 and 6 were predictive of worst renal function at 1st and 3rd years posttransplant and 5-year graft survival. The most important histological finding, in effectively transplanted grafts, was the grade of interstitial fibrosis. Patient survival was not influenced by IBS. Conclusions Higher preimplantation biopsy scores predicted an increased risk of early graft losses, especially primary nonfunction. Graft survival (at 1st and 5th years after transplant) but not patient survival was predicted by IBS

The relationship between Marcel Proust and Joseph Babinski: the encounter of two geniuses

Marcel Proust was one of the greatest French writers of all times. Since early in his life, Proust was interested in arts and particularly literature. He also demonstrated a great knowledge of medicine, particularly neurology. His father was a doctor, and contributed to neurology through studies on aphasia, stroke, hysteria, and neurasthenia. During his childhood, Proust had the first asthma attack, initially considered a manifestation of neurasthenia. Regarding his illness, Proust was in touch with several renowned neurologists, such as Brissaud, Babinski and Sollier, and other disciples of Charcot. Proust spent the last three years of his life mostly confined to his bedroom since his health had badly deteriorated. in one moment, Babinski was called, examined Proust and after leaving his bedroom, announced to his brother that Proust was practically dead. Few hours later, Proust developed vomica and died.Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)Universidade Federal de São Paulo, Dept Neurol, Setor Neurol Geral & Ataxias, São Paulo, BrazilUniv Fed Parana, Hosp Clin, Serv Neurol, Setor Disturbios Movimento, BR-80060000 Curitiba, Parana, BrazilUniv Fed Minas Gerais, Dept Interno Med, Serv Neurol, Setor Disturbios Movimento, Belo Horizonte, MG, BrazilUniversidade Federal de São Paulo, Dept Neurol, Setor Neurol Geral & Ataxias, São Paulo, BrazilWeb of Scienc

Boas práticas hídricas na produção leiteira.

bitstream/item/79662/1/Comunicado101.pd