1,002 research outputs found
Argyres-Douglas Loci, Singularity Structures and Wall-Crossings in Pure N=2 Gauge Theories with Classical Gauge Groups
N=2 Seiberg-Witten theories allow an interesting interplay between the
Argyres-Douglas loci, singularity structures and wall-crossing formulae. In
this paper we investigate this connection by first studying the singularity
structures of hyper-elliptic Seiberg-Witten curves for pure N=2 gauge theories
with SU(r+1) and Sp(2r) gauge groups, and propose new methods to locate the
Argyres-Douglas loci in the moduli space, where multiple mutually non-local BPS
states become massless. In a region of the moduli space, we compute dyon
charges for all 2r+2 and 2r+1 massless dyons for SU(r+1) and Sp(2r) gauge
groups respectively for rank r>1. From here we elucidate the connection to the
wall-crossing phenomena for pure Sp(4) Seiberg-Witten theory near the
Argyres-Douglas loci, despite our emphasis being only at the massless sector of
the BPS spectra. We also present 2r-1 candidates for the maximal
Argyres-Douglas points for pure SO(2r+1) Seiberg-Witten theory.Comment: 81 pages, 41 figures, LaTeX; v2: Minor cosmetic changes and
correction of a typographical error in acknowledgement. Final version to
appear in JHE
General Argyres-Douglas Theory
We construct a large class of Argyres-Douglas type theories by compactifying
six dimensional (2,0) A_N theory on a Riemann surface with irregular
singularities. We give a complete classification for the choices of Riemann
surface and the singularities. The Seiberg-Witten curve and scaling dimensions
of the operator spectrum are worked out. Three dimensional mirror theory and
the central charges a and c are also calculated for some subsets, etc. Our
results greatly enlarge the landscape of N=2 superconformal field theory and in
fact also include previous theories constructed using regular singularity on
the sphere.Comment: 55 pages, 20 figures, minor revision and typos correcte
The Hilbert Series of the One Instanton Moduli Space
The moduli space of k G-instantons on R^4 for a classical gauge group G is
known to be given by the Higgs branch of a supersymmetric gauge theory that
lives on Dp branes probing D(p + 4) branes in Type II theories. For p = 3,
these (3 + 1) dimensional gauge theories have N = 2 supersymmetry and can be
represented by quiver diagrams. The F and D term equations coincide with the
ADHM construction. The Hilbert series of the moduli spaces of one instanton for
classical gauge groups is easy to compute and turns out to take a particularly
simple form which is previously unknown. This allows for a G invariant
character expansion and hence easily generalisable for exceptional gauge
groups, where an ADHM construction is not known. The conjectures for
exceptional groups are further checked using some new techniques like sewing
relations in Hilbert Series. This is applied to Argyres-Seiberg dualities.Comment: 43 pages, 22 figure
The Puf family of RNA-binding proteins in plants: phylogeny, structural modeling, activity and subcellular localization
<p>Abstract</p> <p>Background</p> <p>Puf proteins have important roles in controlling gene expression at the post-transcriptional level by promoting RNA decay and repressing translation. The Pumilio homology domain (PUM-HD) is a conserved region within Puf proteins that binds to RNA with sequence specificity. Although Puf proteins have been well characterized in animal and fungal systems, little is known about the structural and functional characteristics of Puf-like proteins in plants.</p> <p>Results</p> <p>The Arabidopsis and rice genomes code for 26 and 19 Puf-like proteins, respectively, each possessing eight or fewer Puf repeats in their PUM-HD. Key amino acids in the PUM-HD of several of these proteins are conserved with those of animal and fungal homologs, whereas other plant Puf proteins demonstrate extensive variability in these amino acids. Three-dimensional modeling revealed that the predicted structure of this domain in plant Puf proteins provides a suitable surface for binding RNA. Electrophoretic gel mobility shift experiments showed that the Arabidopsis AtPum2 PUM-HD binds with high affinity to BoxB of the Drosophila Nanos Response Element I (NRE1) RNA, whereas a point mutation in the core of the NRE1 resulted in a significant reduction in binding affinity. Transient expression of several of the Arabidopsis Puf proteins as fluorescent protein fusions revealed a dynamic, punctate cytoplasmic pattern of localization for most of these proteins. The presence of predicted nuclear export signals and accumulation of AtPuf proteins in the nucleus after treatment of cells with leptomycin B demonstrated that shuttling of these proteins between the cytosol and nucleus is common among these proteins. In addition to the cytoplasmically enriched AtPum proteins, two AtPum proteins showed nuclear targeting with enrichment in the nucleolus.</p> <p>Conclusions</p> <p>The Puf family of RNA-binding proteins in plants consists of a greater number of members than any other model species studied to date. This, along with the amino acid variability observed within their PUM-HDs, suggests that these proteins may be involved in a wide range of post-transcriptional regulatory events that are important in providing plants with the ability to respond rapidly to changes in environmental conditions and throughout development.</p
Nonabelian Faddeev-Niemi Decomposition of the SU(3) Yang-Mills Theory
Faddeev and Niemi (FN) have introduced an abelian gauge theory which
simulates dynamical abelianization in Yang-Mills theory (YM). It contains both
YM instantons and Wu-Yang monopoles and appears to be able to describe the
confining phase. Motivated by the meson degeneracy problem in dynamical
abelianization models, in this note we present a generalization of the FN
theory. We first generalize the Cho connection to dynamical symmetry breaking
pattern SU(N+1) -> U(N), and subsequently try to complete the Faddeev-Niemi
decomposition by keeping the missing degrees of freedom. While it is not
possible to write an on-shell complete FN decomposition, in the case of SU(3)
theory of physical interest we find an off-shell complete decomposition for
SU(3) -> U(2) which amounts to partial gauge fixing, generalizing naturally the
result found by Faddeev and Niemi for the abelian scenario SU(N+1) -> U(1)^N.
We discuss general topological aspects of these breakings, demonstrating for
example that the FN knot solitons never exist when the unbroken gauge symmetry
is nonabelian, and recovering the usual no-go theorems for colored dyons.Comment: Latex 30 page
Noncommutative geometry inspired black holes in higher dimensions at the LHC
When embedding models of noncommutative geometry inspired black holes into
the peridium of large extra dimensions, it is natural to relate the
noncommutativity scale to the higher-dimensional Planck scale. If the Planck
scale is of the order of a TeV, noncommutative geometry inspired black holes
could become accessible to experiments. In this paper, we present a detailed
phenomenological study of the production and decay of these black holes at the
Large Hadron Collider (LHC). Noncommutative inspired black holes are relatively
cold and can be well described by the microcanonical ensemble during their
entire decay. One of the main consequences of the model is the existence of a
black hole remnant. The mass of the black hole remnant increases with
decreasing mass scale associated with noncommutative and decreasing number of
dimensions. The experimental signatures could be quite different from previous
studies of black holes and remnants at the LHC since the mass of the remnant
could be well above the Planck scale. Although the black hole remnant can be
very heavy, and perhaps even charged, it could result in very little activity
in the central detectors of the LHC experiments, when compared to the usual
anticipated black hole signatures. If this type of noncommutative inspired
black hole can be produced and detected, it would result in an additional mass
threshold above the Planck scale at which new physics occurs.Comment: 21 pages, 7 figure
Mutation Symmetries in BPS Quiver Theories: Building the BPS Spectra
We study the basic features of BPS quiver mutations in 4D
supersymmetric quantum field theory with gauge symmetries.\ We show,
for these gauge symmetries, that there is an isotropy group
associated to a set of quiver mutations capturing
information about the BPS spectra. In the strong coupling limit, it is shown
that BPS chambers correspond to finite and closed groupoid orbits with an
isotropy symmetry group isomorphic to the discrete
dihedral groups contained in Coxeter with the
Coxeter number of G. These isotropy symmetries allow to determine the BPS
spectrum of the strong coupling chamber; and give another way to count the
total number of BPS and anti-BPS states of gauge theories. We
also build the matrix realization of these mutation groups from which we read directly the electric-magnetic
charges of the BPS and anti-BPS states of QFT as well as
their matrix intersections. We study as well the quiver mutation symmetries in
the weak coupling limit and give their links with infinite Coxeter groups. We
show amongst others that is contained in
; and isomorphic to the infinite Coxeter
. Other issues such as building
and are also
studied.Comment: LaTeX, 98 pages, 18 figures, Appendix I on groupoids adde
Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy.
BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease of right ventricular morphology, as well as in a rodent model of right ventricular hypertrophy (RVH).MethodsHomogenates of right ventricle (RV) explants from non-failing controls and children born with a SV were assayed for HDAC catalytic activity and HDAC isoform expression. Postnatal 1-day-old rat pups were placed in hypoxic conditions, and echocardiographic analysis, gene expression, HDAC catalytic activity, and isoform expression studies of the RV were performed.ResultsClass I, IIa, and IIb HDAC catalytic activity and protein expression were elevated in the hearts of children born with a SV. Hypoxic neonatal rats demonstrated RVH, abnormal gene expression, elevated class I and class IIb HDAC catalytic activity, and protein expression in the RV compared with those in the control.ConclusionsThese data suggest that myocardial HDAC adaptations occur in the SV heart and could represent a novel therapeutic target. Although further characterization of the hypoxic neonatal rat is needed, this animal model may be suitable for preclinical investigations of pediatric RV disease and could serve as a useful model for future mechanistic studies
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