17,557 research outputs found
Funding and providing social services: The good, the bad and the third way?
The funder/provider split in the area of social services is now a long-established reality in Aotearoa/New Zealand. It has been the subject of much debate and criticism see, for example, Boston et at 1996. However, it remains the principal means by which a range of NGO service providers gains access to State funding. At the same time, with the advent of a new Labour-Alliance coalition government in 1999, the possibility arises that one of the social policy reforms the government might consider would be to amend or even to abolish the funder/provider system
When does an ostrich become a bird? The role of typicality in early word comprehension
Which objects and animals are are children willing to accept as referents for words they know? To answer this question, the authors assessed early word comprehension using the preferential looking task. Children were shown 2 stimuli side by side (a target and a distractory) and heard the target stimulus named. The target stimulus was either a typical or an atypical exemplar of the named category. It was predicted that children first connect typical examples with the target name and broaden the extension of the name as they get older to include less typical examples. Experiment 1 shows that when targets are named, 12-month-olds display an increase in target looking for typical but not atypical targets whereas 24-month-olds display an increase for both. Experiment 2 shows that 18-month-old display a pattern similar to that of 24-month-olds. Implications for the early development of word comprehension are discussed
Comparison of growing media for container grown plants
Greenhouse and growth chamber experiments are conducted worldwide in efforts to produce solutions that would increase yields of agronomic crops. However, the results of those experiments vary due to the many growth media being used. An experiment was conducted in the fall of 2010 to identify a broadly acceptable growth media that would produce uniform stands and optimum results in greenhouse and growth chamber settings. A total of six growth media were tested on cotton (Gossypium hirsutum) at the Arkansas Agricutural Research and Extension Center’s Altheimer Lab in Fayetteville. The plants grown in each medium were harvested six weeks after planting and the measurements performed included plant height, plant dry matter, leaf area, and nutrient analysis. The results indicated that a positive, significant difference (P \u3c 0.05) existed between “Sunshine” mix (MIX1) and the other media. Plants grown in MIX1 experienced greater plant height, dry matter, leaf area, and also experienced higher leaf tissue levels of N, P, and S. “Sunshine” (Mix1) is a readily available growth medium that produces optimum plant growth and uniform results in growth chamber and greenhouse experiments
Lactobacillus ruminis strains cluster according to their mammalian gut source
peer-reviewedBackground
Lactobacillus ruminis is a motile Lactobacillus that is autochthonous to the human gut, and which may also be isolated from other mammals. Detailed characterization of L. ruminis has previously been restricted to strains of human and bovine origin. We therefore sought to expand our bio-bank of strains to identify and characterise isolates of porcine and equine origin by comparative genomics.
Results
We isolated five strains from the faeces of horses and two strains from pigs, and compared their motility, biochemistry and genetic relatedness to six human isolates and three bovine isolates including the type strain 27780T. Multilocus sequence typing analysis based on concatenated sequence data for six individual loci separated the 16 L. ruminis strains into three clades concordant with human, bovine or porcine, and equine sources. Sequencing the genomes of four additional strains of human, bovine, equine and porcine origin revealed a high level of genome synteny, independent of the source animal. Analysis of carbohydrate utilization, stress survival and technological robustness in a combined panel of sixteen L. ruminis isolates identified strains with optimal survival characteristics suitable for future investigation as candidate probiotics. Under laboratory conditions, six human isolates of L. ruminis tested were aflagellate and non-motile, whereas all 10 strains of bovine, equine and porcine origin were motile. Interestingly the equine and porcine strains were hyper-flagellated compared to bovine isolates, and this hyper-flagellate phenotype correlated with the ability to swarm on solid medium containing up to 1.8% agar. Analysis by RNA sequencing and qRT-PCR identified genes for the biosynthesis of flagella, genes for carbohydrate metabolism and genes of unknown function that were differentially expressed in swarming cells of an equine isolate of L. ruminis.
Conclusions
We suggest that Lactobacillus ruminis isolates have potential to be used in the functional food industry. We have also identified a MLST scheme able to distinguish between strains of L. ruminis of different origin. Genes for non-digestible oligosaccharide metabolism were identified with a putative role in swarming behaviour.This work was supported by a Principal Investigator Award (07/IN.1/B1780)
from Science Foundation Ireland to P.W. O’Toole
Review of: Music Education in the Middle Ages and the Renaissance by Russell E. Murray, Susan Forscher Weiss, and Cynthia J. Cyrus
A review of the book Music Education in the Middle Ages and the Renaissance, by Russell E. Murray, Susan Forscher Weiss, and Cynthia J. Cyrus, as part of the Publications of the Early Music Institute series, is presented
Cultivating creativity: building the creative and cultural industries of North-East Scotland.
Keynote speech delivered at Cultivating Creativity, Sowing Seeds: Growing Networks Conference, held at Robert Gordon University, Aberdeen on 20th May 2011
Possible attenuation of the G2 DNA damage cell cycle checkpoint in HeLa cells by extremely low frequency (ELF) electromagnetic fields
BACKGROUND:
The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part responsible for the increased incidence of leukaemia in parts of the population exposed to them.
METHODS:
Combined treatment of HeLa cells with gamma-irradiation (1, 3 and 5 Grays) and extra low frequency magnetic fields of ~50 Hz was carried out under rigorously controlled conditions.
RESULTS:
Synchronised cells progressing from S-phase arrived at mitosis on average marginally ahead of irradiation controls not exposed to ELF. In no instance out of a total of twenty separate experiments did this "double-insult" further delay entry of cells into mitosis, as had been anticipated.
CONCLUSION:
This apparently "non-genotoxic" agent (ELF) appears to be capable of affecting cells that would normally arrest for longer in G2, suggesting a weakening of the stringency of the late cycle (G2) checkpoint
Modelling the motion of clusters of cells in a viscous fluid using the boundary integral method
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