E-ABR in patients with cochlear implant: A comparison between patients with malformed cochlea and normal cochlea

OBJECTIVES: This study aims to compare the electrical auditory brainstem response (EABR) following cochlear implant (CI) surgery in pediatric subjects with cochlear malformation and a normal cochlea, in order to assess the sensitivity of EABR and to evaluate the surgery outcome. MATERIALS and METHODS: A total of 26 pediatric subjects who were deaf and scheduled for CI surgery were enrolled into this case control study. Group A (n=20) included subjects with a normo-conformed cochlea. Group B (n=6) included subjects with cochlear malformation. Subjects were evaluated with EABR immediately (T0) and 6 months (T1) post-CI surgery. The EABR Waves III and V average amplitude and latency were compared across time, separately for each group, and across groups, separately for each time. RESULTS: Auditory brainstem response (ABR) could only be recorded in Group A. We were able to record EABR from all subjects at T0 and T1, and waves III and V were present in all the recorded signals. There were no statistically significant differences between T0 and T1 in EABR Waves III and V in terms of average amplitude and latency in neither group. When comparing Groups A and B, the only statistically significant difference was the average amplitude of wave V, both at T0 and T1. CONCLUSION: EABR is a valid tool to measure the auditory nerve integrity after CI surgery in patients with a normal and malformed cochlea, as shown by its ability to measure waves III and V when ABR is absent. The EABR testing should be performed before and after CI surgery, and EABR should be used as a measure of outcome, especially in patients with a malformed cochlea

Advanced radar absorbing ceramic-based materials for multifunctional applications in space environment

In this review, some results of the experimental activity carried out by the authors on advanced composite materials for space applications are reported. Composites are widely employed in the aerospace industry thanks to their lightweight and advanced thermo-mechanical and electrical properties. A critical issue to tackle using engineered materials for space activities is providing two or more specific functionalities by means of single items/components. In this scenario, carbon-based composites are believed to be ideal candidates for the forthcoming development of aerospace research and space missions, since a widespread variety of multi-functional structures are allowed by employing these materials. The research results described here suggest that hybrid ceramic/polymeric structures could be employed as spacecraft-specific subsystems in order to ensure extreme temperature withstanding and electromagnetic shielding behavior simultaneously. The morphological and thermo-mechanical analysis of carbon/carbon (C/C) three-dimensional (3D) shell prototypes is reported; then, the microwave characterization of multilayered carbon-filled micro-/nano-composite panels is described. Finally, the possibility of combining the C/C bulk with a carbon-reinforced skin in a synergic arrangement is discussed, with the aid of numerical and experimental analyses

Finite-size effects and collective vibrations in the inner crust of neutron stars

We study the linear response of the inner crust of neutron stars within the Random Phase Approximation, employing a Skyrme-type interaction as effective interaction. We adopt the Wigner-Seitz approximation, and consider a single unit cell of the Coulomb lattice which constitutes the inner crust, with a nucleus at its center, surrounded by a sea of free neutrons. With the use of an appropriate operator, it is possible to analyze in detail the properties of the vibrations of the surface of the nucleus and their interaction with the modes of the sea of free neutrons, and to investigate the role of shell effects and of resonant states

The duration of the school-to-work transition in Italy and in other European countries: a flexible baseline hazard interpretation

Purpose: The Italian school-to-work transition (STWT) is astonishingly slow and long in comparison to the other EU countries. We analyze its determinants comparing the Italian case with Austria, Poland and the UK. Design/methodology/approach: The analysis is based on a Cox survival model with proportional hazard. The smoothed hazard estimates allow us to identify the nonlinear path of the hazard function. Findings: The authors reckon that the actual length of the transition to a stable job is around 30 months in Italy. Conversely, it is less than one year in the other countries. Women are particularly penalized, despite being on average more educated than men. Tertiary or vocational education at high secondary school strongly increases the hazard rate to a regular job. The smoothed hazard estimates suggest positive duration dependence at the beginning of the transition and slightly negative thereafter. Practical implications: Stimulating economic growth and investing in education and training are important pre-conditions for shortening the transition. Originality/value: Despite the duration of the STWT is one of the most important indicators to measure the efficiency of the STWT, it is not easy to measure. The authors build on their previous research work on this topic, but relaxing the assumption of a monotonic hazard rate and using the flexible baseline hazard approach to test for the existence of nonlinear duration dependence. Furthermore, they extend the analysis by including student-workers who attended a vocational path of education, in order to detect its effectiveness in allowing young people finding a job sooner

Near-infrared spectroscopy study of tourniquet-induced forearm ischaemia in patients with coronary artery disease

Near-Infrared Spectroscopy (NIR) can be employed to monitor local changes in haemodynamics and oxygenation of human tissues. A preliminary study has been performed in order to evaluate the NIRS transmittance response to induced forearm ischaemia in patients with coronary artery disease (CAD). The population consists in 40 patients with cardiovascular risk factors and angiographically documented CAD, compared to a group of 13 normal subjects. By inflating and subsequently deflating a cuff placed around the patient arm, an ischaemia has been induced and released, and the patients have been observed until recovery of the basal conditions. A custom LAIRS spectrometer (IRIS) has been used to collect the backscattered light intensities from the patient forearm throughout the ischaemic and the recovery phase. The time dependence of the near-infrared transmittance on the control group is consistent with the available literature. On the contrary, the magnitude and dynamics of the NIRS signal on the CAD patients show deviations from the documented normal behavior, which can be tentatively attributed to abnormal vessel stiffness. These preliminary results, while validating the performance of the IRIS spectrometer, are strongly conducive towards the applicability of the NIRS technique to ischaemia analysis and to endothelial dysfunction characterization in CAD patients with cardiovascular risk factors.Publisher PD

Effects of atomic oxygen and UV rays ageing on the reflection coefficient of carbon/carbon plates in the 12-18 GHz frequency range

Advanced carbon-based ceramic materials, such as Carbon/Carbon (C/C) are commonly employed in aerospace industry to face the thermo-mechanical stress suffered by the spacecraft external structures during re-entry in earth atmosphere. Thanks to very low thermal expansion and outstanding chemical stability at extreme temperatures, in fact, such materials represent the ideal candidates for re-usable space integrated systems, such as TPS, nozzles and ablation thermal-proof structures. In long-time missions, on the other hand, issues related to continuous and extended exposure of the spacecraft surfaces to the detrimental space environment must be carefully considered. In this frame, also the tracking of satellites by mean of radar systems is a vital aspect for a safe stay in space. In LEO working conditions, the combined effects induced by severe thermal cycles, ultra-high vacuum and UV/Atomic Oxygen(AO) irradiation can be of impediment for the use of C/C as re-entry protection material, since a significant surface oxidation leads to so high TPS damaging as to compromise its main functionality. This surface oxidation can also affect the radar visibility of satellites. Aim of this paper is to evaluate the effects of the AO/UV ageing on C/C plates reflection coefficient, in order to avoid misfunctioning in the radar visibility

Linear response of light deformed nuclei investigated by self-consistent quasiparticle random-phase-approximation

We present a calculation of the properties of vibrational states in deformed, axially--symmetric even--even nuclei, within the framework of a fully self--consistent Quasparticle Random Phase Approximation (QRPA). The same Skyrme energy density and density-dependent pairing functionals are used to calculate the mean field and the residual interaction in the particle-hole and particle-particle channels. We have tested our software in the case of spherical nuclei against fully self consistent calculations published in the literature, finding excellent agreement. We investigate the consequences of neglecting the spin-orbit and Coulomb residual interactions in QRPA. Furthermore we discuss the improvement obtained in the QRPA result associated with the removal of spurious modes. Isoscalar and isovector responses in the deformed ${}^{24-26}$Mg, $^{34}$Mg isotopes are presented and compared to experimental findings

A general aspect-term-extraction model for multi-criteria recommendations

In recent years, increasingly large quantities of user reviews have been made available by several e-commerce platforms. This content is very useful for recommender systems (RSs), since it reflects the users' opinion of the items regarding several aspects. In fact, they are especially valuable for RSs that are able to exploit multi-faceted user ratings. However, extracting aspect-based ratings from unstructured text is not a trivial task. Deep Learning models for aspect extraction have proven to be effective, but they need to be trained on large quantities of domain-specific data, which are not always available. In this paper, we explore the possibility of transferring knowledge across domains for automatically extracting aspects from user reviews, and its implications in terms of recommendation accuracy. We performed different experiments with several Deep Learning-based Aspect Term Extraction (ATE) techniques and Multi-Criteria recommendation algorithms. Results show that our framework is able to improve recommendation accuracy compared to several baselines based on single-criteria recommendation, despite the fact that no labeled data in the target domain was used when training the ATE model

Optimized random phase approximations for arbitrary reference systems: extremum conditions and thermodynamic consistence

The optimized random phase approximation (ORPA) for classical liquids is re-examined in the framework of the generating functional approach to the integral equations. We show that the two main variants of the approximation correspond to the addition of the same correction to two different first order approximations of the homogeneous liquid free energy. Furthermore, we show that it is possible to consistently use the ORPA with arbitrary reference systems described by continuous potentials and that the same approximation is equivalent to a particular extremum condition for the corresponding generating functional. Finally, it is possible to enforce the thermodynamic consistence between the thermal and the virial route to the equation of state by requiring the global extremum condition on the generating functional.Comment: 8 pages, RevTe