Comportamento de genótipos de girassol no município de Campo Verde, Mato Grosso, na safra de 2009.

O girassol (Helianthus annuus L.) é originário da América do Norte e tem como principal produto o óleo de excelente qualidade extraído de suas sementes, utilizado para consumo humano, para diversos fins industriais ou como matéria prima para produção de biocombustíveis. Este trabalho teve como objetivo verificar o comportamento de genótipos de girassol do ensaio final de segundo ano, da Rede de Ensaios de Avaliação de Genótipos de Girassol, na safra de 2009, visando indicação para cultivo em Mato Grosso. Foi conduzido experimento no município de Campo Verde-MT, seguindo delineamento em blocos ao acaso com quatro repetições, para verificar o desempenho de dezoito genótipos de girassol. As parcelas foram formadas por quatro linhas de 6,0 m, com espaçamento de 0,9 m x 0,30 m. Foram registradas as características de desenvolvimento das plantas e após a colheita, os capítulos foram debulhados manualmente e efetuadas as determinações de peso de mil aquênios, do total de aquênios, do teor de óleo nos aquênios e calculado o rendimento de óleo (rendimento de aquênios x teor de óleo). Os dados foram submetidos à análise estatística e as médias comparadas pelo teste de Duncan a 5%. O genótipo Neon apresentou melhor desempenho que os demais, tanto para peso de mil aquênios como para rendimento de aquênios, com médias de 80 g e de 4267 kg/ha, respectivamente. Quanto ao rendimento de óleo a média geral do experimento foi de 1230 kg/ha, com melhor desempenho apresentado pelos genótipos Neon, NTO 3.0, HLT 5004, Paraiso 20, Triton Max, Exp 1450 HO, SRM 822 e V20041, com valores entre 1680 kg/ha e 1313 kg/ha. Com base nos resultados obtidos, esses genótipos de girassol apresentam potencial para cultivo em Mato Grosso. THE BEHAVIOR OF SUNFLOWER GENOTYPES IN CAMPO VERDE, MATO GROSSO, 2009 HARVEST. The sunflower (Helianthus annus L.) is native from North America and the main product it provides is the high quality oil extracted from its seeds, used for human consumption, industrial purposes or as base for biofuel production. This project aims to verify the behavior of the sunflower genotypes from the second year?s final essay, belonging to Rede de Ensaios de Avaliação de Genótipos (Network of Genotype Evaluation Essays), 2009 harvest, with the purpose of obtaining indication for use in Mato Grosso. The experiment was conducted in the town of Campo Verde-MT, following the lineation in random blocks with four repetitions as a means to verify the performance of eighteen sunflower genotypes. The portions were formed by four lines of 6,0m each, with spacing of 0,9m x 0,30m. Aspects of development from the plants were analyzed and, after the harvest, sunflowers were manually threshed and a series of determinations of was established: the weight of a thousand achenes, the total of achenes, the percentage of oil from the achenes and the oil efficiency was calculated (achenes efficiency x oil percentage). Data was statistically analyzed and the standards were compared by the Duncan test at 5%. The Neon genotype presented the most satisfactory performance, in both 1,000 achenes weight and achenes efficiency standards, with measures of 80g and 4,267kg/ha, respectively. Regarding the oil efficiency, the overall average was 1230kg/ha, with best efficiency present by the Neon genotypes NTO 3,9, HLT 5004, Paraíso 20, Triton Max, Exp 1450 HO, SRM 822 and V20041, with values between 1680kg/ha and 1313kg/ha. Based on the results, it?s safe to say the abovementioned sunflower genotypes present high potential for cultivation in Mato Grosso

Características agronômicas de genótipos de girassol, na Safra de 2010, em Mato Grosso.

O cultivo de girassol (Helianthus annuus L.) vem se expandindo no Brasil, sobretudo na região central do país, como alternativa na época de ?safrinha?. O presente trabalho teve por objetivo avaliar as características agronômicas e o potencial de cultivo de genótipos de girassol do ensaio final de segundo ano, da Rede de Ensaios de Avaliação de Genótipos de Girassol, na safra de 2010. Foi realizado experimento em Campo Verde, Mato Grosso, para avaliação de dezessete genótipos, seguindo delineamento em blocos ao acaso, com quatro repetições, com parcelas formadas por quatro linhas de 6,0 m, com espaçamento de 0,9 m x 0,25 m. Foram registradas as medidas de altura de plantas e diâmetro de capítulos na época da floração. Os capítulos foram colhidos e debulhados manualmente, sendo realizadas as determinações de peso de mil aquênios, do total de aquênios, do teor de óleo nos aquênios e calculado o rendimento de óleo (rendimento de aquênios x teor de óleo). Os resultados foram submetidos à análise de variância e as médias foram comparadas pelo teste de Duncan a 5%. A média de peso de mil aquênios foi de 67 g, com o genótipo BRS-Gira 24 destacando-se frente aos demais com 77 g. O genótipo HLA 887 apresentou o melhor comportamento quanto ao rendimento de aquênios (3619 kg/ha), teor de óleo (48,3%) e rendimento de óleo (1745 kg/ha). Os genótipos V 50070, V 70003 e BRS-Gira 27 também apresentaram bom desempenho para rendimento de aquênios. Por meio das avaliações realizadas é possível a indicação de genótipos de girassol para cultivo em Mato Grosso. AGRONOMIC TRAITS OF SUNFLOWER GENOTYPES DURING THE 2010 HARVEST IN MATO GROSSO. The cultivation of sunflower (Helianthus annuus L.) has expanded in Brazil, especially in the country?s central, as an alternative during the period of ?safrinha?. The project has the purpose of evaluating the agronomic traits and the cultivation potential of the sunflower genotypes from the second year?s final essay, belonging to Rede de Ensaios de Avaliação de Genótipos (Network of Genotype Evaluation Essays), 2010 harvest. The experiment was conducted in the town of Campo Verde-MT, for the evaluation of seventeen genotypes, following the lineation in random blocks with four repetitions and portions formed by four lines of 6,0m each, with spacing of 0,9m x 0,25m. Measures of height from the plants and the diameter of the sunflowers in period of bloom were registered. The sunflowers were harvested and manually threshed, then a series of determinations of was established: the weight of a thousand achenes, the total of achenes, the percentage of oil from the achenes and the oil efficiency was calculated (achenes efficiency x oil percentage). Data was submitted to variance analysis and the standards were compared by the Duncan test at 5%. The standard weight of a thousand achenes was 67g, and the BRS-Gira 24 genotype was the highlight with 77g. The HLA 887 genotype presented the best behavior as regarding the achenes efficiency (3619kg/ha), oil percentage (48,3%) and oil efficiency (1745kg/ha). The V 50070, V 70003 and BRS-Gira 27 genotypes also presented a satisfactory performance as to what concerns the achenes efficiency. Through the evaluations realized, it?s possible to indicate the sunflower genotypes for cultivation in Mato Grosso

Development of a Computational Tool for the Analysis of Hydro-Sanitary Designs

The high demand for hydro-sanitary designs to be analyzed by the public system, in addition to the long time it takes to complete such analyses, reveals that the employed verification methodology and bureaucratic procedures are obsolete. The main objective of this work was to develop a computational tool for releasing and analyzing hydro-sanitary systems, seeking to automate the process. The methodology was initiated with the creation of an electronic archive of the rules and laws pertinent to the subject, followed by the identification of the work routines for hydro-sanitary designs, the programming of the tool, the creation of an electronic repository for objects and, finally, the validation of the software through testing. As a result, the computational model will automatically retrieve project data in the BIM platform and assess information of designs developed in CAD. Based on this work, the conclusion can be drawn that the automation of the release and analysis processes of hydro-sanitary designs is possible and achievable

Comportamento de genótipos de girassol em Mato Grosso, na safra de 2011.

Resumo: O girassol apresenta características desejáveis sob o ponto de vista agronômico: ciclo curto, tolerância à seca e bom rendimento em óleo. Seu cultivo tem como principal produto o óleo de excelente qualidade extraído de suas sementes. O objetivo do trabalho foi verificar o comportamento de genótipos de girassol, em ensaio final de segundo ano da Rede de Ensaios de Avaliação de Genótipos de Girassol, na safra de 2011, visando indicação para cultivo em Mato Grosso. Foi conduzido experimento em Campo Verde - MT, seguindo delineamento em blocos ao acaso com quatro repetições e parcelas de quatro linhas de 6,0 m, com espaçamento de 0,9 m x 0,25 m, avaliando-se dez genótipos. Foram obtidas avaliações de altura de planta, diâmetro de capítulo, peso de mil aquênios, rendimento de aquênios, teor de óleo e rendimento de óleo. As médias dos resultados foram comparadas pelo teste de Duncan a 5%. Por meio das avaliações realizadas, os genótipos M734, CF 101, QC 6730, GNZ CIRO, HLA 11-26 e HELIO 358 apresentam características favoráveis para cultivo em Mato Grosso. Abstract: The sunflower presents advantageous characteristics from an agronomic perspective: short cycle, tolerance to drought and good oil yield. The main product of its cultivation is the high quality oil extracted from its seeds. The purpose of this study is to verify the behavior of sunflower genotypes, under final testing of the second year by the Network of Evaluative Experiments with Sunflower Genotypes in the crop of 2011, proposing an indication for cultivation in the state of Mato Grosso, Brazil. Experiment was conducted in Campo Verde - MT, based on the delimitation of random blocks, with four repetitions and arrays of four lines 6,0 m each and spacing of of 0,9 m x 0,25 m, evaluating ten genotypes. The average values of the results were compared using the Duncan test at 5%. According to the evaluations carried out, the genotypes M734, CF 101, QC 6730, GNZ CIRO, 11-26 and HLA HELIO 358 present favorable characteristics for cultivation in Mato Grosso

Gold Nanoparticle-Based Surface-Enhanced Raman Scattering for Noninvasive Molecular Probing of Embryonic Stem Cell Differentiation

This study reports the use of gold nanoparticle-based surface-enhanced Raman scattering (SERS) for probing the differentiation of mouse embryonic stem (mES) cells, including undifferentiated single cells, embryoid bodies (EBs), and terminally differentiated cardiomyocytes. Gold nanoparticles (GNPs) were successfully delivered into all 3 mES cell differentiation stages without affecting cell viability or proliferation. Transmission electron microscopy (TEM) confirmed the localization of GNPs inside the following cell organelles: mitochondria, secondary lysosome, and endoplasmic reticulum. Using bright- and dark-field imaging, the bright scattering of GNPs and nanoaggregates in all 3 ES cell differentiation stages could be visualized. EB (an early differentiation stage) and terminally differentiated cardiomyocytes both showed SERS peaks specific to metabolic activity in the mitochondria and to protein translation (amide I, amide II, and amide III peaks). These peaks have been rarely identified in undifferentiated single ES cells. Spatiotemporal changes observed in the SERS spectra from terminally differentiated cardiomyocyte tissues revealed local and dynamic molecular interactions as well as transformations during ES cell differentiation

The Speeches of Frank M. Coffin: A Sideline to Judging

The Authors of this Article are engaged in a separate project to publish the full collection of law-related speeches delivered by Judge Coffin during his tenure on the bench. That collection in its entirety consists of more than 125 speeches, and it is a treasure trove of thoughts on the judiciary as an institution, the law, judging, the legal profession, legal education, and legal luminaries past and present. The speeches are also worthy of study purely as examples of communication, advocacy, speechcraft, composition, humor, and whimsy. Within the confines of this Article, the modest goal is to provide samples of the delights that await the lawyer, judge, public speaker or citizen who turns to the full collection for guidance and inspiration in pursuing the cause of justice or merely in crafting a memorable speech. Few will ever equal Judge Coffin’s ability to shape words to serve a purpose and motivate action

Temozolomide-Acquired Resistance Is Associated with Modulation of the Integrin Repertoire in Glioblastoma, Impact of α5β1 Integrin

Despite extensive treatment, glioblastoma inevitably recurs, leading to an overall survival of around 16 months. Understanding why and how tumours resist to radio/chemotherapies is crucial to overcome this unmet oncological challenge. Primary and acquired resistance to Temozolomide (TMZ), the standard-of-care chemotherapeutic drug, have been the subjects of several studies. This work aimed to evaluate molecular and phenotypic changes occurring during and after TMZ treatment in a glioblastoma cell model, the U87MG. These initially TMZ-sensitive cells acquire long-lasting resistance even after removal of the drug. Transcriptomic analysis revealed that profound changes occurred between parental and resistant cells, particularly at the level of the integrin repertoire. Focusing on α5β1 integrin, which we proposed earlier as a glioblastoma therapeutic target, we demonstrated that its expression was decreased in the presence of TMZ but restored after removal of the drug. In this glioblastoma model of recurrence, α5β1 integrin plays an important role in the proliferation and migration of tumoral cells. We also demonstrated that reactivating p53 by MDM2 inhibitors concomitantly with the inhibition of this integrin in recurrent cells may overcome the TMZ resistance. Our results may explain some integrin-based targeted therapy failure as integrin expressions are highly switchable during the time of treatment. We also propose an alternative way to alter the viability of recurrent glioblastoma cells expressing a high level of α5β1 integrin