18 research outputs found
The role of laparoscopy and laparoscopic ultrasound in the preoperative staging of pancreatico-biliary cancers – A meta-analysis
A national perspective on the decline of abdominoperineal resection for rectal cancer
Objective: To assess rates of abdominoperineal excision of the rectum (APER) for rectal cancer between centers and over time, and to evaluate the influence of patient characteristics, including social deprivation, on,APER rate. Methods: Data on patients undergoing APER or anterior resection (AR) in England were extracted from a national administrative database for the years 1996 to 2004. The primary outcome was the proportion of patients presenting with rectal cancer undergoing APER. Hierarchical logistic regression was used to identify independent factors associated with a nonrestorative resection. Results: Data on 52,643 patients were analyzed, 13,109(24.9%) of whom underwent APER. The APER rate significantly reduced over the study period from 29.4% to 21.2% (P < 0.001). Operative mortality following AR decreased significantly during the period of study (5. 1 % to 4.2%, P = 0.002), while that following APER did not (P = 0.075). Male patients were more likely to undergo APER (P < 0.001), whereas those with an emergency presentation more commonly underwent AR (P < 0.00 1). Independent predictors of increased APER rate were male gender (odds ratio [OR] = 1.239, P < 0.001) and social deprivation (most vs. least deprived; OR 1.589, P < 0.001), whereas increasing patient age (OR = 0.977, P = 0.027 per 10-year increase), year of study (2003/4 vs. 1996/7; OR = 0.646, P < 0.001) and initial presentation as an emergency (OR = 0.713, P < 0.001) were associated with lower APER rates. After accounting for case-mix, there was significant between-center variability in APER rates. Conclusion: Socially deprived patients were more likely to undergo abdominoperineal resection. Significant improvements in rates of nonrestorative resection were seen over time but although short-term outcomes following AR have improved, those following APER have not. Permanent stoma rates following rectal cancer surgery may be considered a surrogate marker of surgical qualit
External Validity of a Mortality Prediction Model in Patients After Open Abdominal Aortic Aneurysm Repair Using Multi-level Methodology
Número de gânglios dissecados em peças pperatórias de pacientes submetidos à ressecção cirúrgica de câncer colorretal: retrospectiva de 10 anos HNSC - Tubarão - SC Number of lymph nodes dissecated on operatory samples of patients submited to surgical colorectal cancer resection: ten years retrospective review - Tubarão / SC
No que se refere ao CCR, a análise dos linfonodos regionais é de suma importância visto que atua como fator prognóstico para a doença, determinando ou não a necessidade de terapia adjuvante, sendo que o número sugerido pela literatura varia entre 6 a 30 linfonodos identificados no espécime. Foi objetivo do trabalho determinar o número de linfonodos analisados em peças operatórios através de laudos histo-patológicos de pacientes submetidos a tratamento cirúrgico de câncer colorretal, por adenocarcinoma. A média de idade encontrada foi de 58,69 anos. Setenta e cinco pacientes eram do sexo feminino (56,8%). A maioria se encontrava em estadio da doença T3 (75%). 70 pacientes tiveram diagnóstico de adenocarcinoma bem diferenciado; dentre eles, 27 (42,2%) apresentaram gânglios positivos. CONCLUSÃO: A média de gânglios dissecados foi de 11,21 / peça operatória, sendo que a probabilidade de encontrarmos nodos positivo é maior quando mais de 10 gânglios foram pesquisados. A média de linfonodos positivos foi maior quando o adenocarcinoma é do tipo indiferenciado.<br>Lymph node analysis is very important in colorectal cancer since it is a prognosis factor for the disease, which will either determine the needs of adjuvant therapy, or not. The amount of identified lymph nodes per specimen suggested by the literature varies from 6 to 30. The purpose of this work was to show the amount of lymph nodes analyzed from operatory subjects by means of the histopathology records from patients undergoing colorectal cancer surgical treatment from adenocarcinoma. The average age found was 58,69 years. Seventy five patients were females (56,8%). Most patients were found to be in phase T3 of the disease (75%). Sixty four patients had a very differentiated adenocarcinoma. Among them, 27 (42,2%) showed positive nodes. CONCLUSION: The average of dissected lymph nodes was of 11,21 / specimen. Being that the probability of finding positive node was greater when 10 or more nodes were analyzed. The average of positive lymph node was greater in undifferentiated adenocarcinoma